Clinical trials: Eye
Glaucoma, Open Angle Glaucoma
Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma Surgery
The purpose of this study is to evaluate the long-term safety and performance of the ARGOS-SC system.
- Trial name
- NCT04773106
- Testing
- ARGOS-SC suprachoroidal pressure sensor
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 22 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Alzheimer's Disease, Healthy Controls
Development of Eye-movement Based Biomarkers in Alzheimer's Disease
This study aims to develop and validate a sensitive and non-invasive eye-tracking software application. This study will obtain participant responses to brief cognitive tests designed to evaluate several key functions known to be…
- Trial name
- NCT05176704
- Testing
- Eye-Tracking
- Where
- 5 sites in Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- McGill University
Progressive Keratoconus
Evaluation of Corneal Hysteresis and Corneal Resistance Factor After Corneal Cross-linking for Keratoconus
This study attempts to compare Corneal Hysteresis (CH) and Corneal Resistance Factor (CRF) in a series of keratoconic eyes before and after Corneal collagen cross-linking (CXL).
- Trial name
- NCT01411384
- Testing
- Corneal collagen cross-linking, Ocular Response Analyzer (ORA)
- Volunteers
- 80 people
- Sponsor
- Democritus University of Thrace
Glaucoma, Open Angle, Pseudo-exfoliative, Cataract
Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation
Pseudoexfoliative glaucoma is a glaucoma secondary to pseudoexfoliative syndrome; cataract surgery is often more difficult, with more complications.
- Trial name
- NCT06979752
- Testing
- Tran canula, augmented irrigation
- Where
- 3 sites in France
- Volunteers
- 58 people
- Sponsor
- Hôpital Privé de la Baie
Glaucoma Congenital
Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery
Long term Surgical Outcomes of Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery. Purpose: This study aims to compare outcomes of single-site rigid probe viscotrabeculotomy (VT) to two-site VT in pediatric…
- Trial name
- NCT05011747
- Testing
- single-site rigid probe viscotrabeculotomy (VT), two-site rigid probe viscotrabeculotomy (VT)
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Eye Injury Trauma
Adjunctive Steroid Combination in Ocular Trauma (ASCOT) Study
Eye trauma is a leading cause of blindness and visual impairment. Penetrating injuries of the eye are more likely to result in poor vision and the main cause of this is a scarring response on the retina (proliferative…
- Trial name
- ASCOT (NCT02873026)
- Testing
- Triamcinolone Acetonide
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Skin Toxicities
Development of Dermatology-related Quality of Life Assessment in Patients Treated With Epidermal Growth Factor Receptor (EGFR) Inhibitors
Epidermal Growth Factor Receptor Inhibitors (EGFRI) are associated with skin toxicities. Clinical experience suggests that skin toxicities interfere with health related quality of life (HRQL) and may interfere with treatment…
- Trial name
- FAST (NCT01015326)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Healthy Volunteer
PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects
An open label, multiple-dose, phase 1 clinical trial to evaluate pharmacokinetics, pharmacodynamics, safety and tolerability of PHP-201 topical eye drop in Korean and Japanese healthy subjects
- Trial name
- NCT03586908
- Testing
- PHP-201 0.5% ophthalmic solution (topical eye drop)
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- pH Pharma
Cataract
Safety and Surgical Performance Study of Aurosleek Surgical Blades
To evaluate the safety and surgical effectiveness of surgical blades (Aurosleek) made by Aurolab.
- Trial name
- Aurosleek (NCT01763593)
- Where
- India
- Volunteers
- 35 people
- Sponsor
- Aurolab
Cataract, Anxiety
Evaluation of the Effectiveness of Stress Ball Practice During Cataract Surgery
Cataract surgery is one of the most commonly performed and reliable surgeries among eye diseases. While cataract surgeries were performed under general or local anesthesia in previous years, they are now performed topically.
- Conditions
- Cataract, Anxiety, Pain
- Trial name
- NCT05847114
- Testing
- Stres ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ege University
Dry Eye Disease
Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome
The study is designed to assess the safety and efficacy of Vismed®, a special eye drop containing sodium hyaluronate, in the treatment of dry eye syndrome.
- Trial name
- NCT00599716
- Testing
- sodium hyaluronate, vehicle
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Lantibio
Dry Eye, Dry Eye Disease
PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms
Dry eye disease (DED), also called keratoconjunctivitis sicca, is a multifactorial disease of the ocular surface characterized by loss of homeostasis of the tear film and accompanied by symptoms such as ocular discomfort and…
- Conditions
- Dry Eye, Dry Eye Disease, Kerato Conjunctivitis Sicca
- Trial name
- NCT05825352
- Testing
- Carmellose eye drops
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- C.O.C. Farmaceutici S.r.l.
Cataract, Vision
Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs
The purpose of this study is to evaluate and compare the depth of focus and visual outcomes after implantation of the Acrysof IQ SN60WF aspheric intraocular lens (IOL) and the Acrysof Natural SN60AT spherical IOL.
- Trial name
- NCT00886249
- Testing
- Acrysof IQ, Acrysof Natural IOL
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Neuritis
RESting-state Functional MRI in Patients With Optic Neuritis for ANticipation of reCovEry
When patients arrive in the waiting room of the MRI department, patients will be given the briefing note explaining the purpose of the study and how it is going.
- Trial name
- RESONANCE (NCT04448938)
- Testing
- MRI, visual acuity
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Aging
Heart Aging When Near Vision Difficulty Begins
Near vision deterioration during aging results from a decrease in accomodation amplitude (AA). Myocardial regeneration is limited, and cardiac aging is an independent risk factor for cardiovascular disease.
- Trial name
- NCT04362215
- Testing
- Subjective accomodation amplitude measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Cerebral Stroke, Cerebral Venous Thrombosis
Intracranial Hypertension and Optic Nerve Sheath Diameter
Intracranial hypertension (ICH) is a mortality risk factor in severe traumatic brain injury (TBI), in purulent meningitis, in hepatic encephalopathy and in Reye's syndrome.
- Trial name
- DENO (NCT01796015)
- Testing
- ONSD ultrasound
- Where
- 2 sites in France
- Volunteers
- 230 people
- Sponsor
- Hospices Civils de Lyon
Glaucoma
A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery
This is a pilot study, which will include approximately five eyes of 5 patients. This study proposes that a sustained release steroid insert (Yutiq)1 be implanted along with a glaucoma drainage device (Ahmed Glaucoma Valve (AGV)…
- Trial name
- NCT04918121
- Testing
- Yutiq 0.18 MG Drug Implant
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sanjay Asrani
Uveitis, Macular Edema
Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial
The Macular Edema Ranibizumab v. Intravitreal anti-inflammatory Therapy (MERIT) Trial will compare the relative efficacy and safety of intravitreal methotrexate, intravitreal ranibizumab, and the intravitreal dexamethasone…
- Trial name
- MERIT (NCT02623426)
- Testing
- Dexamethasone intravitreal implant 0.7 mg, Intravitreal Methotrexate 400 µg, Intravitreal Ranibizumab 0.5 mg
- Where
- 33 sites in United States, Australia and 3 more
- Volunteers
- 194 people
- Sponsor
- JHSPH Center for Clinical Trials
Age-related Cataract, Vision Loss
Long-term Safety & Performance of REVISYON SDS100 in Mild to Moderate Cataract: Extension Study (EB-CE-02)
A non-interventional, extension study on the long-term maintenance of safety and performance of the REVISYON SDS 100 medical device in subjects with mild-to-moderate cataract.
- Conditions
- Age-related Cataract, Vision Loss, Cataract, Mild Cataract
- Trial name
- EB-CE-02 (NCT07246915)
- Where
- 6 sites in Romania
- Volunteers
- 47 people
- Sponsor
- Edinburgh Biosciences Ltd
Visual Fatigue
The Effect of 3D Autostereoscopic Video-game Play on the Visual Fatigue in Children
This study aims to examine the specific effect that 3D game play has on the control of the eyes horizontal movements. It will examine the youngest group of consumers this technology is marketed to, 7 to 11-year-olds and no…
- Trial name
- NCT02407015
- Testing
- Nintendo 3DS gameplay
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
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