Clinical trials: Eye Disorders
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Eye Infections
Comparative Efficacy of Different Regimens of PVPI 5% Eye Drops Instillation in Reducing Conjunctival Bacterial Flora
The present study intends to assess the efficacy of 3 drops of 5% povidone-iodine (PVPI) eyedrops in reducing the bacterial flora in a conjunctival sac fundus compared to the standard procedure consisting of the application of 1…
- Trial name
- NCT01739920
- Testing
- Povidone-iodine, Saline Solution
- Where
- Brazil
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dry Eye Disease, Ocular Surface Disease
Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF
This is a phase I study evaluating safety and tolerability of PRO-229 ophthalmic solution through he incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), incidence of chemosis, and changes in…
- Trial name
- NCT06370585
- Testing
- PRO-229, Lagricel® Ofteno PF
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Pseudotumor Cerebri
Optic Nerve Sheath Diameters in Idiopathic Intracranial Hypertension Patients
Idiopathic intracranial hypertensionis a type of increased intracranial pressure. Diagnosis is made by lumbar puncture, which is an invasive technique.
- Trial name
- NCT04603118
- Testing
- Optic ultrasonography, Lumbar puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ege University
Keratoconus
Topography Versus Non-Topography-Guided PRK With CXL in Keratoconus
To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL)…
- Trial name
- keratoconus (NCT03890718)
- Testing
- Photorefractive keratectomy in mile keratoconus
- Where
- Iran
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Glaucoma
Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma
The purpose of this study is to determine if an optokinetic contrast detection device is sufficient to measure contrast sensitivity and to distinguish between patients with and without glaucoma.
- Trial name
- HOCD (NCT02014597)
- Testing
- HOCD
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Benjamin Frankfort, MD, PhD
Optic Nerve Sheath Diameter, Pneumoperitoneum
Comparison of Changes of ONSD Between Groups of Laparoscopic Surgery With and Without Epidural Saline Injection
This study targets patients undergoing laparoscopic gastric cancer surgery. The investigators would like to compare two factors that influence intracranial pressure through optic nerve sheath diameter measurement.
- Conditions
- Optic Nerve Sheath Diameter, Pneumoperitoneum, Epidural
- Trial name
- NCT04758013
- Testing
- Epidural injection through thoracic epidural catheter, Without epidural injection
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Keimyung University Dongsan Medical Center
Blepharoptosis, Synkinesis
Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis
After an episode of facial paralysis, as nerves recover, they aberrantly regenerate and send additional branches to the incorrect muscles in addition to the intended muscle.
- Conditions
- Blepharoptosis, Synkinesis, Hyperkinesis, Facial Paralysis
- Trial name
- NCT05945615
- Testing
- Oxymetazoline 0.1% (Pf) Oph Soln Ud, Preservative free lubricating drops
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Vision, Low, Mobility Limitation
Evaluating Stairway Designs for Individuals With Vision Impairment
The goal of this study is to learn if contrast frequency on step tread-edges influences foot clearance measures, a marker of fall risk, in older adults with and without visual impairments.
- Trial name
- NCT07337317
- Testing
- Frequency of contrast marking on stair steps
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Alabama in Huntsville
Dry Eye, Sjogren's Disease
Multi-Colored Placido Disk Viability
The purpose of this study is to show that the multi-colored Placido Disk set-up can get reliable data over long time periods.
- Conditions
- Dry Eye, Sjogren's Disease, Healthy
- Trial name
- NCT02148497
- Testing
- Multi-colored Placido disk imaging
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Glaucoma, Ocular Hypertension
Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)
To compare Combigan Two Times Daily (BID) vs Simbrinza Three Times Daily (TID) in subjects currently being treated with Latanoprost for Open-Angle Glaucoma or Ocular Hypertension.
- Trial name
- NCT02167035
- Testing
- Combigan Two Times Daily (BID), Simbrinza Three Times Daily (TID)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Cornerstone Health Care, PA
Conjunctivitis, Bacterial, Keratitis Bacterial
Microbiologic Alterations of the Conjunctiva of Hot Tub-soaking Ophthalmologists
The purpose of this study is to determine if there are microbiologic alterations of the ocular surface after hot tub exposure. The study will evaluate the number of microbes before and after hot tub use in order to find out…
- Trial name
- MACHO (NCT03987178)
- Testing
- Dunk, Exposure to Hot Tub
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pterygium
Evaluation of Tranilast to Treat Pterygium Before Excision
Recurrent or secondary pterygium often has often a growing fibrovascular tissue more exuberant than the primary. Histological findings differ from the primary, since the typical changes in the degenerate connective tissue are…
- Trial name
- TPS (NCT01003613)
- Testing
- Tranilast, and Tissucol, Beriplast P
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Gildasio Castello de Almeida Junior
Lymphoma, Salivary Gland Disease
Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome
This study will follow patients with salivary gland dysfunction to identify the long-term course of this disorder and its effects on the mouth, oral function, and overall health.
- Conditions
- Lymphoma, Salivary Gland Disease, Sjogren's Syndrome, Xerostomia
- Trial name
- NCT00001852
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Diabetic Retinopathy, Macular Degeneration
Screening for Studies on Retinovascular Diseases
This screening protocol is designed to help recruit patients for National Eye Institute (NEI) studies of the retina, such as diabetic retinopathy and macular degeneration.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Pathologic Neovascularization, Retinal Disease
- Trial name
- NCT00001733
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Macular Degeneration, Glaucoma
An Open Study Comparing the Effects of Moxaverine on Ocular Blood Flow in Patients With Age- Related Macular Degeneration, Primary Open Angle Glaucoma and Healthy Control Subjects
A number of common eye diseases such as age-related macular degeneration and glaucoma are associated with ocular perfusion abnormalities.
- Conditions
- Macular Degeneration, Glaucoma, Regional Blood Flow
- Trial name
- NCT00709449
- Testing
- moxaverine
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hearing Impairment
Do Bluetooth Noise Cancelling Headphones Improve the Quality of Care in Hearing Impaired Patients?
Participants will be recruited by performing chart reviews of patients to be seen at University of Texas Medical Branch at Galveston Ophthalmology and Optometry Clinic. A sample size of at least 30 patients is needed (60 eyes).
- Trial name
- NCT05420038
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cataract
Veracity Surgical: A Time/Motion and Quality of Care Study
This study aims to compare the time required for surgical planning using these two methods and to explore whether differences in surgical accuracy can be identified in a small study of 40 patients.
- Trial name
- NCT04337892
- Testing
- Standard of Care4
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
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