Clinical trials: Eye Disorders
Clinically Isolated Syndrome, Relapsing Remitting Multiple Sclerosis
Implementation of a Novel Functional Eye-Tracking Biomarker for Multiple Sclerosis
This study aims to develop and validate a sensitive and non-invasive eye-tracking software application. This study will obtain participant responses to brief cognitive tests designed to evaluate several key functions known to be…
- Trial name
- NCT05277740
- Testing
- Eye-tracking
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University
Healthy Volunteers, Alzheimer Disease
Phase 1 Test-retest Evaluation of [18F]MNI-958 PET
The overall goal of this protocol is to evaluate [18F]MNI-958 also known as APN-0000455 or PM-PBB3, a tau targeted radiopharmaceutical.
- Conditions
- Healthy Volunteers, Alzheimer Disease, Progressive Supranuclear Palsy
- Trial name
- NCT03545789
- Testing
- [18F]MNI-958
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Invicro
Keratoconus, Corneal Ectasia
Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal Ectasia
Corneal collagen crosslinking (CXL) has been demonstrated as an effective method of reducing progression of both keratoconus and corneal ectasia after surgery, as well as possibly decreasing the steepness of the cornea in these…
- Trial name
- NCT04905108
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cornea and Laser Eye Institute
Myopia
Noninvasive and Dynamic Monitoring the Biological Parameters of Eyes in Different Age Groups
Myopia is the most common refractive eye disease worldwide. The number of cases is up to 2 billion. In recent years, the incidence of myopia in China is obviously rising trend.
- Trial name
- NCT05250440
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Poly Cystic Ovary Syndrome
The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
This is a Descriptive prospective cohort study conducted at the Ophthalmology Department in Kasr-Alaini Hospital. A total of 90 subjects, 30 control females with no relevant medical, gynecological or ophthalmic history, and 60…
- Trial name
- NCT07419776
- Testing
- dry eye diagnostic system of Mediworks, Optical coherence tomography angiography, Contraceptives, Oral, Combined
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myopia
Peripheral Choroidal Layer Response
The study aims to examine how the vascular layer of the eyeball (choroidal layer) responds when part of the visual field is exposed to specially generated visual stimulus.
- Trial name
- NCT05132140
- Testing
- adaptive optics system
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Houston
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses
This study aims to compare the short-term clinical performance of the three contact lenses (Methafilcon A IV, Ocufilcon B 1-day and Omafilcon A 1-day daily disposable).
- Trial name
- NCT03235115
- Testing
- Methafilcon A IV, Ocufilcon B, Omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Macular Degeneration
Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60
This study will explore whether taking the vitamins lutein and zeaxanthin, with or without Omega-3 fatty acid (fish oil or docosahexanoic acid, also known as DHA) will change the amount of lutein and zeaxanthin in the blood among…
- Trial name
- NCT00121589
- Testing
- Lutein
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Dry Eye Disease, Immunity
Efficacy of Twinkle Eyez Supplementation in Improving Ocular Health and Immunity
This is a randomised, double-blind, placebo-controlled study that recruited 110 participants. The objectives of this study are to determine the dietary intake levels of lutein and zeaxanthin among precipitants.
- Trial name
- NCT06574685
- Testing
- Twinkle Eyez Supplementation
- Where
- Malaysia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ecolite Group
Ocular Surface Disease, Central Retinal Artery Occlusion
Effects of HFMH-EMS on Ocular Artery Circulation
Investigated the effects of high-frequency multi-band harmonic electromagnetic stimulation on ophthalmic and central retinal artery circulation.
- Trial name
- NCT06861985
- Testing
- BOBY, Control
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Glaucoma, Optic Neuropathy, Ischemic
Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases
In the management of glaucoma, as for as in other optic nerve diseases, an important goal of ophthalmologists is represented by the possibility of influencing visual function.
- Conditions
- Glaucoma, Optic Neuropathy, Ischemic, Visual Pathway Disorder, Optic Nerve
- Trial name
- NCT00404729
- Testing
- Citicoline
- Where
- 2 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up)
Postoperative CCT in FECD vs. Non-FECD
This single-centre, prospective, controlled, non-interventional observational clinical study aims to characterize early postoperative corneal thickness behaviour after routine phacoemulsification cataract surgery in eyes with…
- Trial name
- NCT07731945
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vienna Hospital Association
Myopia, Refractive Errors
Peripheral Defocus Profile of Multifocal Minus Contact Lenses
Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia…
- Conditions
- Myopia, Refractive Errors, Contact Lens
- Trial name
- NCT06335212
- Testing
- Single vision and multifocal contact lenses
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Dry Eye Syndromes
ACCURATE Study for Subjects With Dry Eyes
To determine treatment and imaging outcomes in bilateral ocular surface disease management with an intracanalicular dexamethasone (0.4 mg) insert compared to standard topical over-the-counter artificial tears lubrication…
- Trial name
- ACCURATE (NCT04237012)
- Testing
- Dextenza 0.4Mg Intracanalicular Insert, Over the counter Artificial tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Eye Centers of Racine and Kenosha
Ocular Injury
An Observational, Qualitative Study Assessing Eye Drop Administration
This is a prospective, observational, consecutive, qualitative, multicenter study. Based on the available published evidence that supports patient challenges with eyedrop administration, the purpose of this video-capture study is…
- Trial name
- NCT05307081
- Testing
- Artificial Tears
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ocular Therapeutix, Inc.
Cataract
Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3
A prospective evaluation of the visual parameters in a series of patients bilaterally implanted with AcrySof ReSTOR +3 Intraocular Lens (IOL).
- Trial name
- NCT00719732
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Near Vision
Pharmacological Treatment of Presbyopia
In this clinical trial, a total of 75 presbyopic patients in the age range of 40 to 60 years old will be participated. The right eyes of 45 patients will be treated by Biocarpine® and they will be considered as the case group…
- Trial name
- NCT05564832
- Testing
- Pilocarpine 1.25% Eye drop
- Where
- Iran
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma; Drugs
CATS Tonometer IOP Reduction Latanoprost Verses Timolol
Topical Prostaglandin Analog vs Betablocker - Corneal Biomechanical Evaluation using CATS Tonometer Prism
- Trial name
- NCT04178863
- Testing
- CATS Tonometer, Latanoprost
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Intuor Technologies, Inc.
Glaucoma
Intraocular Pressure (IOP) Lowering Efficacy of Transdermal Latanoprost Therapy
The purpose of this study is to evaluate the safety and effectiveness in lowering intraocular pressure (IOP) utilizing an experimental lotion containing 0.005% Latanoprost that is applied to the outside of one eyelid.
- Trial name
- NCT01426464
- Testing
- 0.005% Latanoprost dosed once.
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Nanduri, Padma, M.D., FACS
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