Clinical trials: Eye Disorders
Glaucoma
Effectiveness of a Procedure for Previously Failed Glaucoma Surgery
Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years.
- Trial name
- NCT00347789
- Testing
- Glaucoma surgery- Bleb revision
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glaucoma Research & Education Group
Myopia
Clinical Trial of Orthokeratology Lens (MCOK-01)
A prospective, multicenter, randomized, controlled clinical trial of orthokeratology lens
- Trial name
- NCT06037850
- Testing
- Test orthokeratology lens, Control orthokeratology lens
- Where
- 3 sites in Singapore
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Branch Retinal Vein Occlusion, Retinal Blood Flow
Assessment of Retinal Vessel Diameters and Red Blood Velocities in Patients With BRVO and Healthy Subjects
Assessment of retinal vessel calibers combined with bidirectional Fourier domain optical coherence tomography (FDOCT) for measurement of retinal blood velocities is a new and sophisticated method for assessing retinal blood flow…
- Conditions
- Branch Retinal Vein Occlusion, Retinal Blood Flow, Retinal Oxygen Saturation
- Trial name
- NCT01746615
- Testing
- Dynamic Vessel Analyzer, Bidirectional Fourier-Domain Optical Coherence Tomography (FDOCT)
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
Exploring Eye Vergence Markers ADHD) and ASD
The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks.
- Trial name
- NCT06885060
- Testing
- BGaze ADHD Diagnostic Test, Oddball/Alerting Computer Task, Facical Emotion Computer Task
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Elizabeth Kilbey
Vision Disorders, Reading Disabilities
Efficacy of Coloured Overlays and Lenses for Reading Difficulty
This is a randomised controlled trial with the aim of testing the efficacy of coloured overlays and coloured lenses for the relief of visual stress and reading difficulties in children and young adults.
- Trial name
- NCT02680223
- Testing
- Precision tinted lenses, Non-beneficial tinted lenses
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- City, University of London
Keratitis
Ozone-based Eye Drops as Adjuvant Therapy in Microbial Keratitis
To compare the therapeutic effect of ozone-based eye drops as an adjuvant therapy to that of the conventional topical antimicrobial agents in patients with microbial keratitis .
- Trial name
- NCT05689996
- Testing
- Ozone-Based Agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cataract, Lens Opacities
Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort
The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and…
- Conditions
- Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism
- Trial name
- BioBase (NCT05458661)
- Testing
- Clinical Prototype BioBase (SN 07 and SN 08)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Visual Disorder
Premavision Cohort Follow-up
This study aim at following a cohort of prematurely born infants at 18 months corrected age, 4 and 7 years of age. This cohort had an evaluation of visual maturation at term equivalent age (TEA) with factors associated with…
- Trial name
- PrmvsionSuiv (NCT03207477)
- Testing
- Visual acuity measurement
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Juvenile Myopia
Myopia Assessment of Two Manufacturing Processes
Randomized, controlled, multisite, subject- and observer-masked, contralateral clinical trial of 6-month duration to compare two SightGlass Vision Diffusion Optics Technology (DOT) spectacle lens manufacturing processes in…
- Trial name
- MAPLE (NCT04126057)
- Testing
- SightGlass Vision DOT Spectacle Lenses
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Cataract
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation
This study will use dynamic light scattering (DLS) technology to study normal lens aging and early cataract formation. Cataract is a clouding of the lens that interferes with the passage of light to the retina, impairing visual…
- Trial name
- NCT00081991
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Healthy Eyes, Retinal Diseases
Clinical Investigation of a New Version of MAIA Microperimeter on Healthy Subjects and Patients With Retinal Pathology
The purpose of this pre-market, monocentric cross-sectional study is to evaluate the clinical usefulness of a new version of the MAIA device (MAIA) through an agreement with the established version of the MAIA microperimeter…
- Trial name
- NCT06071546
- Testing
- MAIA
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Centervue SpA
Glaucoma
Effect on the Adherence to Glaucoma Eye Drops by Improving Patient Understanding and Using a Tele-reminder System
To determine the improvement in patient adherence to topical ocular hypotensive therapy by introducing a personalised illustrated medication reference chart and tele-reminder.
- Trial name
- NCT04317573
- Testing
- Personalised card
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Alzheimer Disease (AD), Frontotemporal Lobar Degeneration
ADDIA Proof-of-Performance Clinical Study
The objective of the ADDIA clinical Proof-of-Performance study is to validate the performance of ADDIA' blood biomarkers for diagnosis of Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease (AD), Frontotemporal Lobar Degeneration, Dementia with Lewy Bodies (DLB), Parkinson Disease Dementia (PDD)
- Trial name
- ADDIA (NCT03030586)
- Testing
- volumetric MRI
- Where
- 13 sites in Belgium, France and 3 more
- Volunteers
- 821 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Visual Acuity, Presbyopia
Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses
This is a 6-visit, single-masked, multi-site, 2×3 crossover, randomized-controlled, dispensing clinical trial to evaluate visual acuity.
- Trial name
- NCT07076160
- Testing
- INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Evaporative Dry Eye Disease, Meibomian Gland Dysfunction
Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease
The goal of this clinical trial is to evaluate the Eye Lipid Mobilizer (ELM) for the treatment of evaporative dry eye disease associated with meibomian gland dysfunction.
- Trial name
- ELM (NCT06242860)
- Testing
- ELM
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Eyedetec Medical, Inc.
Eye Diseases
Pix2pix Networks for Scheimpflug Corneal Tomography Image Generation
Computer-aided medical image analysis has advantages, but requires large amounts of training data, which are scarce and costly to obtain, are subject to privacy concerns, and are often highly imbalanced, with over-representation…
- Trial name
- NCT04582253
- Testing
- Scheimpflug Camera Corneal Tomography
- Where
- Egypt
- Volunteers
- 923 people, healthy volunteers welcome
- Sponsor
- Assiut University
Blepharitis
Evaluation of SUMMIT BRUSH in Treatment of Blepharitis
Dry Eye Disease (DED) is a multifactorial disease that affects ~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives…
- Trial name
- NCT04603222
- Testing
- SUMMIT BRUSH, Ocusoft Lid Scrub Original Foaming Eyelid Cleanser
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Primary Open- Angle Glaucoma
Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle Glaucoma
This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele.Primary open-angle glaucoma patients and age-matched people in the Han population…
- Trial name
- NCT02805231
- Testing
- Vitamin D receptor polymorphic analysis
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lv Yingjuan
Eye Diseases
Patterns of Eye Diseases Among Patients Attending The Eye Investigation Unit of Sohag University Hospital
The goal of the work: is to assess the patterns of eye diseases in patients attending the eye investigation unit of Sohag University Hospital.organize the community education.
- Trial name
- NCT06812845
- Testing
- eye investigations
- Where
- Egypt
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cataract
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy…
- Trial name
- DEXTENZA (NCT05372315)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iworks Laser and Vision Center