Clinical trials: Eye Disorders
Oral Cancers
Diagnosis of Oral Precancers and Cancers Using Optic Coherence Tomography
Diagnosis of oral precancers and cancers using optic coherence tomography
- Trial name
- NCT00172965
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetic Retinopathy, Diabetic Retinopathy Associated with Type 2 Diabetes Mellitus
Early Retinal Neurodegeneration As Risk Factor, Biomarker and Pharmacological Target of Diabetic Retinopathy
Despite the evidence that diabetic retinopathy (DR) remains the first cause of blindness among the working-age population, it lacks a specific preventive treatment.
- Trial name
- 2022-12376008 (NCT06582472)
- Testing
- Ophthalmological examination including imaging assessments, confocal analysis of cornea, Dynamic Vessel Analyzer (DVA)
- Where
- 2 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Potential Risk Factors and Predictive Model Construction of OBL During SMILE
To explore the prediction of OBL by deep learning model in SMILE surgery
- Trial name
- NCT06577012
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 4,678 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Glaucoma, Dry Eye Syndrome
Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations
This study will be used to evaluate how patients put eye drops in their eyes and any problems that may arise from this activity.
- Conditions
- Glaucoma, Dry Eye Syndrome, Conjunctivitis
- Trial name
- NCT00522600
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Myopia
A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses
The objective of the study is to evaluate the product performance of the Bausch + Lomb toric investigational contact lenses compared to the currently marketed PureVision toric contact lenses.
- Trial name
- NCT01309867
- Testing
- Investigational Toric Lens, PureVision Toric Lens
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Normal Eyes, Eye Abnormalities
The Heidelberg Engineering BI US Evaluation Study
Evaluation of defined parameters measured in pathological and non-pathological eyes with the Heidelberg BI
- Trial name
- NCT03578302
- Testing
- BI Anterior Segment Mode, BI Anterior Segment and IOL Biometry Mode
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism
Small amounts of astigmatism are often uncorrected in contact lens wearers. The effect with respect to driving is unknown, but it could threaten safe operation of a motor vehicle, especially under conditions such as nighttime…
- Trial name
- NCT02624791
- Testing
- 1-DAY ACUVUE® MOIST contact lenses, 1-DAY ACUVUE® MOIST for ASTIGMATISM contact lenses, No contact lenses
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Eyelid Ptoses
The Effect of Varying Brightness on Palpebral Aperture
We aim to establish the point at which glare from bright lights begins to engage our eyelids - causing us to "squint". We will be using a video camera with an LED ring light around it facing the volunteer and we will record the…
- Trial name
- NCT05210491
- Testing
- Review of eyelid positioning in increasing brightness levels
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Keratoconjunctivitis Sicca, Xeropthalmia
Acupuncture Treatment of Dry Eye
The purpose of this study is to determine the safety and efficacy of acupuncture in the treatment of moderate to severe dry eye by replicating the study design of the previous protocol and to see the study through to its…
- Trial name
- NCT00554879
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Amyotrophic Lateral Sclerosis
Ocular Surface Metabolo-lipidomics in Lateral Amyotrophic Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is the most common neurodegenerative disease affecting the motor neuron. Currently, there is no diagnostic test and no examination that can predict the evolution of this pathology.
- Trial name
- LARMOMIQUE (NCT04953286)
- Testing
- Measure of visual acuity, Interferometry, Samples of basal tears
- Where
- 3 sites in France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Open Angle Glaucoma, Cataract
Swedish Microinvasive Glaucoma Surgery Study (SMIGS)
The purpose of the study is to investigate the efficacy of Cataract Surgery as stand-alone compared to Cataract Surgery in combination with Kahook Dual Blade Glide goniotomy (KDB) or iStent Inject W Trabecular Microbypass Stent…
- Conditions
- Open Angle Glaucoma, Cataract, Kahook Dual Blade Glide, Istent Inject W
- Trial name
- SMIGS (NCT05035394)
- Testing
- Cataract surgery, KDB, Istent
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Umeå University
Glaucoma, Ocular Hypertension
EVALUATION of CATS TONOMETER PRISM in LASIK SUBJECTS
The CATS Tonometer prism clinical study is intended to determine repeatability of intraocular pressure measurement in human corneas which have undergone a LASIK procedure when compared to a standard Goldmann prism, validating the…
- Conditions
- Glaucoma, Ocular Hypertension, Normal Tension Glaucoma
- Trial name
- NCT06266351
- Testing
- This is observational IOP measurement
- Where
- 2 sites in United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Intuor Technologies, Inc.
Induced Defocus to the Retina
Defocus Induced Changes on Choroidal Thickness
The goals of this study are to assess the short-term (10-60 minutes) effects of different magnitudes of myopic and hyperopic optical defocus on the transient thickness of the choroid in children and adults, as well as to assess…
- Trial name
- NCT03954886
- Testing
- Plus powered optical lens
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Type 1 Diabetes Mellitus
Endothelial Dysfunction and Diabetes
The aim of the study is to progress in the understanding of the early retinal vascular and neural abnormalities in patients with diabetes, using a new device, the Dynamic Vessel Analyzer.
- Trial name
- DENDI (NCT01097551)
- Testing
- Trinitrin, Neosynephrine 10% collyrium, Iontophoresis with acetylcholine delivery
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endophthalmitis
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
- Trial name
- NCT03244072
- Testing
- Moxifloxacin
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Jason Ahee, M.D.
Glaucoma
Testing Latest Version of NidekRS3000Adv
The investigators would like to know if different imaging devices can improve the quality of images and visualization of imaged tissues.
- Trial name
- NCT03318705
- Testing
- RS3000Adv
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Doheny Image Reading Center
Healthy Subjects
Effect of Oat Compounds on Postprandial Glucose Response
In this project we will investigate synergistic effects of oat polar lipids and beta glucans on postprandial glucose tolerance
- Trial name
- NCT05177172
- Testing
- High beta glucans, Low beta glucans, Low beta glucans + low polar lipids
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Macula Hole
Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)
Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning.
- Trial name
- MARTIAL (NCT03287102)
- Testing
- Macular hole surgery
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Healthy
The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study
The main aim of the present study is to investigate the effects of orally administered vasopressin (AVP) on bottom-up and top-down attentional control to socio-emotional stimuli by combining a validated saccade/antisaccade…
- Trial name
- NCT06329037
- Testing
- Vasopressin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.