Clinical trials: Eye Injuries, open to volunteers
Concussion, Mild, Photophobia
Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity
The purpose of this study is to gather pilot data on the effectiveness of daily disposable tinted contact lenses in reducing photophobia (light sensitivity) following a concussion, with the goal of facilitating the return to work…
- Conditions
- Concussion, Mild, Photophobia, Contact Lens
- Trial name
- NCT07223086
- Testing
- Narrow band (tinted) contact lenses, broad band (clear) contact lenses
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
PTSD - Post Traumatic Stress Disorder
Intermittent Theta-Burst Stimulation (iTBS) as an add-on to Eye Movement Desensitization and Reprocessing (EMDR) in the Treatment of Post-traumatic Stress Disorder (PTSD)
This open-label pilot study will evaluate the feasibility, safety, tolerability, and preliminary clinical outcomes of adding intermittent theta-burst stimulation (iTBS) to Eye Movement Desensitization and Reprocessing (EMDR)…
- Trial name
- NCT07693088
- Testing
- Intermittent Theta-Burst Stimulation (iTBS)
- Where
- 3 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- Aarhus University Hospital
Ocular Pathologies
Compact Auto-Aligning Multi-Modal Eye Imaging to Diagnose Traumatic Eye Injury
The purpose of this study is to test an investigational eye imaging device by taking pictures of participants eyes with a single image capture that takes only seconds.
- Trial name
- NCT07218835
- Testing
- Auto-aligning Ocular imaging instrument
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duke University
Extremely Premature Infant, Anemia Neonatal
Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants
Anemia is a condition in which there are not enough red blood cells to carry oxygen throughout the body. It is very common in extremely preterm infants (born before 28 weeks of pregnancy), and many of these babies require red…
- Conditions
- Extremely Premature Infant, Anemia Neonatal, Blood Transfusion, Umbilical Cord Blood
- Trial name
- NCT07502781
- Testing
- Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Hospital Clinic of Barcelona
Corenal Diseases
A Single-Center Clinical Study to Evaluate the Efficacy and Safety of Sutureless Ophthalmic Hydrogel for Corneal Wound Repair
Corneal blindness is one of the leading causes of blindness worldwide. For various infectious and non-infectious corneal diseases, current clinical repair strategies include corneal lesion debridement, conjunctival flap coverage…
- Trial name
- NCT07638215
- Testing
- Sutureless Ophthalmic Hydrogel for Corneal Stromal Defects
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Suxia Li
Ankle Sprains, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprains, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07728526
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Chemical Burns, Ocular Burns
Treatment of Severe Ocular Chemical Burns by Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells: An Open-Label, Single-Arm, Multicenter Phase II Trial
Severe chemical burns of the eye are serious injuries that can cause intense inflammation of the ocular surface and destroy limbal epithelial stem cells, which are essential for corneal healing.
- Trial name
- SYMBOLCLINICAL (NCT07329569)
- Testing
- Subconjunctival injection of 1 mL with 5 million allogeneic BM-MSCs; one repeat within 21 days.
- Volunteers
- 21 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Visual Field Defect, Stroke
Home-based Vision Rehabilitation Guided by Brain Imaging
The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual…
- Conditions
- Visual Field Defect, Stroke, Hemianopia Homonymous, Quadrantanopia
- Trial name
- BRIGHT (NCT07635329)
- Testing
- High-level perceptual learning-based training, Low-level perceptual learning-based training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Retinal Light Damage, Photic Retinopathy
OCTA Evaluated the Efficacy of Glucocorticoid Retrobulbar Injection in Retinal Photo-injury
The goal of this retrospective observational study is to evaluate the effectiveness of retrobulbar glucocorticoid injection in patients with retinal photo-injury.
- Conditions
- Retinal Light Damage, Photic Retinopathy, Photic Maculopathy
- Trial name
- NCT07869511
- Testing
- retrobulbar injection of glucocorticoid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vision Disorder, Stroke
Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional Study
This cross-sectional observational study aims to characterize acquired visual impairment in adults with acquired brain injury and to examine the relationship between objectively identified visual impairment and self-reported…
- Conditions
- Vision Disorder, Stroke, Brain Injuries
- Trial name
- NCT07858708
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Charles University, Czech Republic
Cardiac Arrest (CA), Anoxic Brain Injury
Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest
WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838.
- Conditions
- Cardiac Arrest (CA), Anoxic Brain Injury, Comatose Survivors of Cardiac Arrest, EEG
- Trial name
- WAKE-OHCA (NCT06979700)
- Testing
- Automated Pupillometry, Transcranial Doppler Ultrasound, Optic Nerve Sheath Diameter
- Where
- 2 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Convergence Insufficiency
Home-based Vision Therapy
Post-concussive vision symptoms affect many Veterans who have experienced traumatic brain injury (TBI). One common issue is trouble with near vision, a problem that may persist long after the acute injury.
- Trial name
- NCT06886737
- Testing
- Virtual-reality convergence training game
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Corneal Epithelial Wound Healing
Evaluation of Dexpanthenol and Hyaluronic Acid Eye Drops on Corneal Epithelialization After Trans Epithelial PRK
The aim of this prospective, contralateral, randomized, double-blind, placebo-controlled study is the evaluation of the performance of a fixed combination of dexpanthenol and hyaluronic acid preservative-free eye artificial tears…
- Trial name
- NCT06822608
- Testing
- dexpanthenol and hyaluronic acid preservative-free eye artificial tears eye drops
- Where
- Greece
- Volunteers
- 68 people
- Sponsor
- National and Kapodistrian University of Athens
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Amblyopia, Amblyopia Unilateral
A Comparative Study of the Efficacy of AR Based Amblyopia Training Therapy and Occlusion Therapy in Older Children and Adults With Amblyopia
The goal of this clinical trial is to investigate the efficacy and safety of dichoptic treatment based on Augmented Reality (AR) technology in treating monocular amblyopia aged 12 to 55 years, and compare dichoptic AR treatment…
- Trial name
- NCT07622576
- Testing
- Augmented Reality glasses, Eye patch
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cancer, Psychological Distress
Feasibility and Efficacy of the EMDR Toolbox Method in Cancer Patients.
The incidence of adverse childhood experiences (ACEs) is significantly elevated in patients affected by organic diseases (Riedl, 2020).
- Trial name
- NCT07481890
- Testing
- STANDARD EMDR, EMDR TOOLBOX METHOD
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- Lega Cancro Ticino