Clinical trials: Eye Manifestations
Visual Impairment
Post-market Evaluation of OdySight App to Monitor Near Visual Acuity at Home (TIL002)
OdySight is a mobile application allowing self-testing of visual parameters including near visual acuity and communication of the data to an online dashboard to patient's doctors.
- Trial name
- TIL002 (NCT05510479)
- Testing
- Software as medical device
- Where
- 3 sites in France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Tilak Healthcare
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Parkinson's Disease, Parkinsonism
VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism
VISMEMO-PD is an observational pilot study aimed at investigating visuospatial memory in reaching space and topographical memory in navigational space in patients with Parkinson's disease and Parkinsonism.
- Conditions
- Parkinson's Disease, Parkinsonism, Multiple System Atrophy, Progressive Supranuclear Palsy
- Trial name
- VISMEMO-PD (NCT07827963)
- Testing
- Multimodal visuospatial and topographical memory assessment
- Where
- 3 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Agitation,Psychomotor
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation
This study designed to evaluate the correlation between the effect of intraoperative magnesium sulfate infusion and the incidence of emergence agitation after pediatric ophthalmic surgery
- Trial name
- NCT03208452
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Amblyopia, Healthy
Amblyopia and Stereoptic Games for Vision
Amblyopia is the most common developmental vision disorder in children, caused by abnormal visual experience in early life, especially a difference in refraction between the eyes, a misalignment of the eye axes, a combination of…
- Trial name
- AMBER (NCT05114252)
- Testing
- Vivid Vision Home, Refractive error correction
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pawel Matusz, PhD
Preterm Birth, Visual Impairment
Eye and Growth in Adolescents Born Moderate-to-late Preterm
During recent years, the interest in studying the risks of being born moderate-to-late preterm (MLP), defined as birth between gestational week 32 to 36, has increased.
- Conditions
- Preterm Birth, Visual Impairment, Eye Abnormalities
- Trial name
- NCT04190147
- Testing
- Structural, functional and metabolic eye examinations
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Vision Disorders
Study of A New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and efficacy of a new investigational cleaning and disinfecting solution (Test) compared to Clear Care cleaning and disinfecting solution (Control) when used by contact lens…
- Trial name
- NCT01318577
- Testing
- Investigational Cleaning & Disinfecting Solution, Clear Care Solution
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Progressive Supranuclear Palsy, Parkinson's Disease
Postural Instability in Progressive Supranuclear Palsy
The purpose of this study is to better understand why individuals with Progressive Supranuclear Palsy (PSP) fall. Understanding the mechanism of gait and balance dysfunction in individuals with PSP may provide us with important…
- Trial name
- NCT01563276
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Healthy, Blindness
Multisensory Body and Space Representations (BASES-EXTINCTION)
To accurately control body movements to interact with objects, our brain needs representations of the body and the nearby space.
- Trial name
- NCT03201341
- Testing
- Electrooculogram (EOG), Surface Electromyography (EMG), Electrodermal response
- Where
- France
- Volunteers
- 1,540 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Blindness, Cerebrovascular Accident
Mechanisms of Human Plasticity in the Human System
The purpose of this study is to investigate the physiology associated with plasticity of the motor system. Plasticity refers to the process by which neighboring brain cells assume the responsibilities of damaged or diseased brain…
- Conditions
- Blindness, Cerebrovascular Accident, Spinal Cord Injury
- Trial name
- NCT00001661
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Amblyopia, Strabismus
Screening for 3-D Visual Disorders in Preschool Children
Visual screening is necessary among pre-school children as they found themselves in a critical period of visual developement. To date, there are no national vision screening program that has been implemented nationwide.
- Conditions
- Amblyopia, Strabismus, Anisometropia
- Trial name
- VISION (NCT05204069)
- Testing
- Instillation of cyclopentolate
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Disorders of Consciousness
Spontaneous Eye Blinking in Disorders of Consciousness
Differential diagnosis between Unresponsive Wakefulness Syndrome (UWS) and Minimally Conscious State (MCS) is complicated due to severe cognitive and/or sensorimotor deficits in these patients.
- Trial name
- Blink-DoC (NCT06323031)
- Where
- 8 sites in Belgium, Germany and 2 more
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Hemianopsia, Homonymous
Testing of a Functional Outcome Measure for Those With Visual Field Defects
This study is designed in two Phases. In phase 1, the Functional Outcome Measure will be tested to determine its validity and reliability in three populations, subjects that have not had a stroke and have no visual field defect…
- Trial name
- FOM (NCT00731796)
- Testing
- Functional Outcome Measure
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NovaVision, Inc.
Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies
A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
This will be a double blind, randomised, placebo controlled, single and multiple oral dose study conducted in 3 parts: Part A, Part B and Part C.
- Conditions
- Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies, MELAS Syndrome, Mitochondrial Myopathies
- Trial name
- NCT03888716
- Testing
- KL1333
- Where
- 2 sites in United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Abliva AB
Vision Disorders, Refractive Errors
Rapid Computerized Visual Acuity Test
A novel computerized visual acuity test was developed and tested on both healthy persons and patients with ocular conditions. Visual acuity outcomes of the computerized test will be compared to the Early Treatment Diabetic…
- Conditions
- Vision Disorders, Refractive Errors, Retinal Disease, Cataract
- Trial name
- NCT05447845
- Testing
- Computerized visual acuity assessment program
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Vision Disorders
Effect of Carotenoids Supplementation on Visual Function in Chinese Subjects
The macula is a pigmented area at the center of the retina, and responsible for the central, high-resolution color vision. Age-related macular degeneration (AMD) is a disease of the macula and is the leading cause of irreversible…
- Trial name
- NCT06098677
- Testing
- Carotenoids supplementation
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Miosis
Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery
This study aim at determining the efficacy of Nepafenac and Ketorolac in obtaining adequate intraoperative mydriasis and preventing miosis during cataract surgery.
- Trial name
- NCT03851172
- Testing
- Ketorolac Ophthalmic, Nepafenac Ophthalmic, Cyclopentolate Ophthalmic
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Visual Impairment, Amblyopia
Developing Better Computerised Vision Tests (CVTV)
Clinical vision measurements usually involve printed charts with an eye care professional interpreting patient responses to generate a score. Those scores determine the need for or outcome of treatment.
- Conditions
- Visual Impairment, Amblyopia, Macular Degeneration, Ophthalmic Disease
- Trial name
- CVTV (NCT06224751)
- Testing
- Near logMAR letter acuity, Near LogMAR word acuity, Red Green Stereoacuity
- Where
- United Kingdom
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Usher Syndrome, Retinitis Pigmentosa
Study of Dietary N-3 Fatty Acids in Patients With Retinitis Pigmentosa and Usher Syndrome
OBJECTIVES: I. Examine the concentration of docosahexanoic acid (DHA) and other n-3 fatty acids in plasma, erythrocyte, and adipose tissue in patients with various forms of retinitis pigmentosa and Usher syndrome. II.
- Trial name
- NCT00004345
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Regional Anesthesia, Horner Syndrome
Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block
The purpose of this study is to assess cerebral blood flow velocity (CBFV) following regional anesthesia for shoulder surgery. The results of this study will help to further understand the physiologic effect of the interscalene…
- Conditions
- Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
- Trial name
- CBF-TCD (NCT04642612)
- Testing
- TCD Measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University