Clinical trials: Eye--Refractive Errors
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Presbyopia
A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia
This is a 4-visit, multi-center, randomized, double-masked, parallel group study evaluating the safety and efficacy of CSF-1 in the treatment of presbyopia.
- Trial name
- NCT03885011
- Testing
- CSF-1, CSF-1 Component #1, CSF-1 Component #2
- Where
- 7 sites in United States
- Volunteers
- 166 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Presbyopia
VisDura VisAbility™ Micro Insert System Pre-market Clinical Trial
The primary study objective is to evaluate the safety and effectiveness of the VisAbility™ Micro Insert System for improvement in binocular distance corrected near visual acuity in presbyopic patients.
- Trial name
- NCT07637500
- Testing
- VisAbility™ Micro Insert System
- Where
- 2 sites in Germany
- Volunteers
- 33 people
- Sponsor
- VisDura, Inc.
Refractive Error
A Non-Treatment Clinical Evaluation of the ELITA Single Piece Patient Interface for Docking Procedure With the ELITA
Open label, prospective, randomized, multicenter, measurement only feasibility study to evaluate the docking procedure using the ELITA Single Piece Patient interface in conjunction with the ELITA system
- Trial name
- NCT06727799
- Testing
- Docking Assessment / Observation
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Study Comparing Eye Growth Over Time in Children Using Two Myopia Control Lenses
The goal of this clinical trial is to investigate the short-term changes in the eye structure while wearing two types of lenslet-based myopia control lenses over a period of 6 months in children aged 6 to 13 years with myopia.
- Trial name
- NCT07253064
- Testing
- MCL 1, MCL 2
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate the Safety and Efficacy of MSENC1 Soft Hydrophilic Contact Lenses and Oxypure Color Soft Hydrophilic Contact Lenses
This project is an open, parallel, randomly controlled, and non-inferiority clinical trial of MSENCI soft hydrophilic contact lenses with Oxypure color soft hydrophilic contact lenses used as the control product.
- Trial name
- NCT06616519
- Testing
- BenQ Materials MSENCI soft hydrophilic contact lenses, Visco Oxypure Color soft hydrophilic contact lenses
- Where
- China
- Volunteers
- 192 people
- Sponsor
- BenQ Materials Corporation
Cataracts, Astigmatism
Investigation of Corneal Aberrations and Visual Outcomes in Patients Implanted With an AcrySof Toric Intraocular Lens (IOL)
A prospective evaluation of postoperative corneal aberrations and visual parameters (e.g. visual acuity) in patients implanted with an AcrySof Toric IOL.
- Trial name
- NCT00878839
- Testing
- Toric
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEM
This study will be a 2-phase, prospective, multicenter, open-label, non-comparative, non-randomized clinical investigation to confirm the safety and effectiveness of the ELITA system.
- Trial name
- NCT05713253
- Testing
- ELITA System
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Astigmatism
Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism
The aim of this study is to compare the clinical performance of the Biofinity Toric (comfilcon A) contact lens, versus Air Optix for Astigmatism (lotrafilcon B) over 1 month of daily wear.
- Trial name
- NCT01965288
- Testing
- comfilcon A, lotrafilcon B
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Myopia
Stellest Lenses and Low-concentration Atropine Myopia Control Among Children
The prevalence of myopia is increasing globally, especially in Asian countries. 70-80% of the young population suffers from myopia, and almost 20% have high myopia.
- Trial name
- NCT06344429
- Testing
- Stellest Lenses, Stellest Lenses+0.05% atropine, Single vision Lenses+0.05% atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor-Polylite Taiwan Co., Ltd.
Myopia
Ophthalmic Compatibility During Seven Days of Continuous Wear of Silicone Hydrogel Lenses
The purpose of this study is to assess the ophthalmic compatibility of three different silicone hydrogel lenses worn on an overnight basis for six nights.
- Trial name
- QUINCE (NCT00934102)
- Testing
- Narafilcon A contact lens, Lotrafilcon A contact lens, Galyfilcon A contact lens
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- CIBA VISION
Refractive Error
Clinical Evaluation of the Safety and Efficacy of FID 120947A
The purpose of this study is to evaluate the safety and efficacy of FID 120947A in soft contact lens wearers of Japanese ethnicity.
- Trial name
- NCT02771145
- Testing
- FID 120947A contact lens disinfecting solution, Soft contact lenses (SCL), SCL preservative solution
- Where
- Japan
- Volunteers
- 91 people
- Sponsor
- Alcon Research
Myopia
Daily Disposable Comparison Study
The objective of the study is to compare the overall subjective preference between two Daily Disposable hydrogel lenses when refitted into a third hydrogel lens.
- Trial name
- NCT02094677
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Comparing the Performance of 1 Day Multifocal Contact Lenses
The objective of the study was to compare the lens handling and performance of Lens A to habitually worn multifocal contact lenses and to the competitor Lens B.
- Trial name
- NCT04449263
- Testing
- Lens A, Lens B, Habitual Lenses
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to assess improvement of palpebral roughness and associated symptoms with 3 months use of Clear Care®.
- Trial name
- NCT01996709
- Testing
- Hydrogen peroxide-based contact lens solution, Habitual contact lens solution, Habitual contact lenses
- Volunteers
- 142 people
- Sponsor
- Alcon Research
Myopia
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
- Trial name
- NCT05285553
- Testing
- MiSight 1 Day, Proclear 1 day
- Where
- 30 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataracts, Astigmatism
Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial
The purpose of this study is to look at the outcomes of your vision after your cataract surgery based on two different types of equipment that will be used during your surgery.
- Trial name
- NCT01279031
- Testing
- Abbott WHITESTAR Signature System with Ellips Transversal Ultrasound, Alcon Infiniti wiht the OZIL Torsional Handpiece
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Innovative Medical
Presbyopia
A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT03017612
- Testing
- Raindrop Near Vision Inlay
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- ReVision Optics, Inc.