Clinical trials: Eye--Refractive Errors
Myopia
A Study to Evaluate the Product Feasibility of Two New Silicone Hydrogel Contact Lenses
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of two RD2135-01 investigational soft contact lenses (Test 1 and Test 2) developed by Bausch + Lomb.
- Trial name
- NCT01583868
- Testing
- B&L RD2135-01 lens C, B&L RD2135-01 lens D, PureVision2
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Presbyopia
Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
Safety and efficacy of POS in participants with presbyopia
- Trial name
- VEGA-3 (NCT06542497)
- Testing
- 0.75% phentolamine ophthalmic solution
- Where
- 39 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Hyperopia
Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm 12 month study, evaluating the safety and effectiveness of the TECHNOLAS TENEO 317 Model 2 (Software version "1.28 US") excimer laser when used in…
- Trial name
- NCT05264623
- Testing
- TENEO 317 Model 2 excimer laser
- Where
- 9 sites in United States
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Performance and Safety of Silicone Hydrogel Soft Contact Lenses
To demonstrate substantial equivalence of the new Silicone Hydrogel Soft Contact Lenses(SHSCL) to the commercially available ACUVUE® VITA™ contact lens
- Trial name
- NCT04226560
- Testing
- 41% Silicone Hydrogel Soft Contact Lenses(SHSCL), ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens, Contact Lens Care Product
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ApexLens Co., Ltd.
Corneal Astigmatism
Retrospective Chart Review of enVista Toric 0.9D Intraocular Lenses
The primary objective of this study is to evaluate the performance of the enVista Toric 0.9D vs non-Toric IOL.
- Trial name
- NCT05075746
- Testing
- enVista Toric, enVista non-Toric (spherical)
- Where
- 3 sites in Canada
- Volunteers
- 302 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan
This study seeks to evaluate the clinical performance of a recently released contact lens designed to correct astigmatism to an established contact lens that has historically been used in these patients.
- Conditions
- Refractive Error, Myopia, Astigmatism
- Trial name
- NCT00639353
- Testing
- senofilcon A toric soft contact lens, senofilcon A sphere soft contact lens
- Where
- 10 sites in Japan
- Volunteers
- 102 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands
The purpose of this study is to evaluate the use of a multifocal contact lens in people who previously wore contact lenses but discontinued due to age-related, near vision demands.
- Trial name
- GARM (NCT00965237)
- Testing
- lotrafilcon B multifocal contact lens, lotrafilcon B single vision contact lens, Over-reader spectacles
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- CIBA VISION
Refractive Error
Corneal Staining Associated With Daily Disposable Beauty Contact Lenses
Limbal ring contact lenses enhance the look of the eye by adding pigmentation in a ring pattern to the contact lens. The purpose of this investigation is to determine if corneal staining increase is dependent upon the lens…
- Trial name
- NCT01882465
- Testing
- etafilcon A, 2-HEMA, EGDMA Non-ionic, hefilcon A
- Where
- Hong Kong
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Visual Outcomes After Presbyopic Lens Exchange
Evaluation of mean preoperative and postoperative Corrected distance visual acuity (CDVA) after Refractive Lens Exchange in presbyopic patients
- Trial name
- RELAX (NCT03790592)
- Testing
- trifocal IOL
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Carl Zeiss Meditec AG
Refractive Errors, Myopia
Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens
The purpose of this clinical study is to assess the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality with frequent…
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04207749
- Testing
- LID015385 contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 18 sites in United States
- Volunteers
- 249 people
- Sponsor
- Alcon Research
Refractive Error
Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial was to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
- Trial name
- NCT01198600
- Testing
- Habitual contact lens, Lotrafilcon B contact lens, Contact lens cleaning and disinfecting system (ClearCare)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- CIBA VISION
Myopia, Cornea
Euclid Phoenix Lens Design Trial
The "first fit" success rate of the current Euclid orthokeratology "MAX" lens design will be compared to that of the new Euclid orthokeratology MAX "Phoenix" lens design in 30 children.
- Trial name
- NCT06389916
- Testing
- Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Presbyopia
Multifocal Contact Lenses Fitting Methods Comparison
The purpose of this study was to compare the clinical performance of two fitting approaches for multifocal contact lenses.
- Trial name
- NCT05734846
- Testing
- Control Lenses (control fitting approach), Test Lenses (test fitting approach)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Presbyopia
VisDura VisAbility™ Micro Insert System Pre-market Clinical Trial
The primary study objective is to evaluate the safety and effectiveness of the VisAbility™ Micro Insert System for improvement in binocular distance corrected near visual acuity in presbyopic patients.
- Trial name
- NCT07637500
- Testing
- VisAbility™ Micro Insert System
- Where
- 2 sites in Germany
- Volunteers
- 33 people
- Sponsor
- VisDura, Inc.
Myopia
Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
The purpose of this clinical trial is to demonstrate that wavefront-guided LASIK is safe and effective for the correction of myopic refractive errors.
- Trial name
- NCT01663363
- Testing
- LASIK correction of myopic refractive errors
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Presbyopia
Investigation of the Presbia Flexivue Microlens™
The Presbia Flexivue Microlens is a corneal inlay.
- Trial name
- NCT02110472
- Testing
- Corneal inlay
- Where
- 11 sites in United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- PresbiBio, LLC
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
APIOC Sphere and APIOC Astigmatism
Vision and comfort, both objective and subjective, will be assessed for single vision contact lens wearers for either the APIOC™ Sphere or the APIOC™ Astigmatism contact lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04806802
- Testing
- APIOC Sphere and APIOC Astigmatism
- Where
- 6 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Myopia
WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap
The purpose of this study is to evaluate the safety and effectiveness of the WaveLight EX500 excimer laser system for the correction of myopia with and without astigmatism using InnovEyes in conjunction with InnovEyes sightmap.
- Trial name
- NCT04219891
- Testing
- WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
- Where
- 9 sites in United States
- Volunteers
- 272 people
- Sponsor
- Alcon Research