Clinical trials: Eye--Refractive Errors
Presbyopia
Evaluation of Functional Superiority of the Morrow eProgressive
Presbyopia is a common age-related condition where the eye loses its ability to focus on nearby objects, typically from around age 45.
- Trial name
- EPACT (NCT07878416)
- Testing
- 3 weeks wearing of study device instead of their current wearing solution
- Where
- 3 sites in Belgium, Italy
- Volunteers
- 50 people
- Sponsor
- Morrow Eyewear
Myopia
Daytime Corneal Swelling During Wear of Narafilcon B Lenses
The purpose of this research is to measure daytime open-eye response to wearing of narafilcon B lenses.
- Trial name
- NCT01444287
- Testing
- narafilcon B, Polymacon, Lotrafilcon A
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Efficacy of the Wavefront Optimized (WFO) Profile in Non-anterior Astigmatisms
The purpose of the study was to assess the efficacy of the Allegretto Wave excimer laser and the wavefront optimized ablation profile in correcting primarily non-anterior astigmatism faults, following laser in-situ keratomileusis…
- Trial name
- NCT01432834
- Testing
- Laser in situ keratomileusis (LASIK), Photorefractive keratectomy (PRK)
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Democritus University of Thrace
Pterygium, Corneal Astigmatism
Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft Transplantation
Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea.
- Trial name
- NCT07198126
- Testing
- Pterygium Excision with Conjunctival Autograft
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Mughal Eye Trust Hospital
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Ametropia
Performance of Toric Hydrogel Lenses Following A Refit With Toric Silicone Hydrogel Lenses for 1 Month
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A toric lenses after a refit with fanfilcon A toric lenses for 1-month of daily wear.
- Trial name
- NCT03835221
- Testing
- methafilcon A toric contact lenses, fanfilcon A toric contact lenses
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process 2
This study is a multi-site, group sequential, adaptive, randomized, double-masked, 2×2 crossover design, 1-week dispensing study.
- Trial name
- NCT03701516
- Testing
- etafilcon A with novel molding process, etafilcon A with current molding process
- Where
- 12 sites in United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.
The purpose of this study is to determine the relative performance of a new daily disposable toric soft contact lens against a daily disposable toric contact lens currently available in market, specifically with regards to the…
- Trial name
- NCT01055132
- Testing
- Etafilcon A toric contact lens, Nelfilcon A toric contact lens
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Myopic Astigmatism
SUPRACOR for Myopia and Myopic Astigmatism
This clinical study has been planned to evaluate the safety and effectiveness of the SUPRACR presbyopic excimer laser treatment algorithm for myopic eyes developed for applying to the cornea of the human eye in a single center.
- Conditions
- Myopia, Myopic Astigmatism, Presbyopia
- Trial name
- SUPRACOR (NCT01404884)
- Testing
- SUPRACOR
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Technolas Perfect Vision GmbH
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refractive Errors
Clinical Comparison of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ contact lenses to Clariti® 1 day contact lenses.
- Trial name
- NCT04865354
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 170 people
- Sponsor
- Alcon Research
Astigmatism, Phacoemulsification
Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism
To compare the effect of Limbal relaxing incisions (LRIs) plus spectacle correction versus spectacle correction alone on subjective and objective improvement in visual function for correcting post phacoemulsification high…
- Trial name
- NCT06896357
- Testing
- Limbal relaxing incisions
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bilateral Cataract, Presbyopia
Symfony/Synergy IOL Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05604781
- Testing
- Symfony & Synergy IOL combination
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Center For Sight
Macular Degeneration, Diabetic Retinopathy
Ocular Discomfort Assessment After Intravitreal Injections
In this study, ocular discomfort following intravitreal injection in naïve patients will be studied, as well as the efficacy of wetting agent (Optive eyewash) to prevent ocular discomfort.
- Conditions
- Macular Degeneration, Diabetic Retinopathy, Retinal Artery Occlusion, Myopia, Degenerative
- Trial name
- EVAGO (NCT02806830)
- Testing
- Optive
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Myopia, Myopia, Progressive
Kubota Glass Parameter Refinement Study
Length of the eye will be measured in subjects exposed to various stimulus characteristics using an electronic spectacle which presents illuminated targets to the eye.
- Conditions
- Myopia, Myopia, Progressive, Vision Disorders
- Trial name
- NCT06085430
- Testing
- Kubota Glass
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Optical Coherence Tomography, Refractive Errors
To Study the Effects of Refractive Surgery on OCT Measurements in the Eye
Corrective eye surgeries, such as Lasik, are widely used to correct focusing problems such as myopia, or nearsightedness. Often these patients develop other conditions like myopic maculopathy or glaucoma which require monitoring…
- Conditions
- Optical Coherence Tomography, Refractive Errors, Myopia
- Trial name
- NCT05856786
- Testing
- Optical coherence tomography
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Refractive Error
A Prospective, Multi-Center Evaluation of Corneal Flap Creation Using Cheetah Femtosecond Laser System and Cheetah Patient Interface
The study is a prospective, open-label, comparative study design that was chosen for the purpose of optimizing the Cheetah settings, and evaluating the Cheetah system quality of LASIK flap.
- Trial name
- NCT03789669
- Testing
- IntraLase iFS femtosecond laser and patient interface, Cheetah femtosecond laser and cheetah patient interface
- Where
- 3 sites in India, Singapore
- Volunteers
- 200 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Presbyopia
Assessment of Near Vision Capacity in Different Light Intensities
Patients who underwent presbyopic correction with bilateral bifocal intraocular lenses implantation are supposed to have sufficient uncorrected vision capacity for activities of daily living (ADLs) that require near vision acuity…
- Trial name
- NCT03024073
- Testing
- BB-Phaco
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Democritus University of Thrace
Refractive Error
Tear Film Evaluation of Dailies® AquaComfort Plus® Multifocal and Toric
The purpose of this study is to evaluate the pre lens tear film characteristics of DAILIES® Aqua Comfort Plus® Multifocal (DACP MF) and Toric (DACP Toric) compared to DAILIES® Aqua Comfort Plus® Sphere (DACP) daily disposable…
- Trial name
- NCT02289742
- Testing
- Nelfilcon A multifocal contact lenses, Nelfilcon A toric contact lenses, Nelfilcon A sphere contact lenses
- Volunteers
- 48 people
- Sponsor
- Alcon Research
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