Clinical trials: Eye--Refractive Errors
Myopia, Astigmatism
Clinical Evaluation of WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07127757
- Testing
- Wavelight Plus LASIK
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Laser Defined Vision
Refractive Error
DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation
The purpose of this study is to evaluate the tear film evaporation of symptomatic soft contact lens wearers in the absence of contact lens wear and after at least 8 hours of contact lens wear.
- Trial name
- NCT02517567
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Myopia, Astigmatism
Randomized, Non-inferiority Trial Comparing SMILE and LASIK
Background: Small Incision Lenticule Extraction or SMILE is a novel form of 'flapless' corneal refractive surgery that was adapted from Refractive Lenticule Extraction (ReLEx).
- Conditions
- Myopia, Astigmatism, Hypermetropia
- Trial name
- NCT01216475
- Testing
- Femtosecond LASIK, Small incision lenticule extraction (SMILE)
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopic Choroidal Neovascularization
Bevacizumab Intravitreal for Myopic Choroidal Neovascularization
To evaluate the clinical results of anti-VEGF intra-vitreal injections (IVT) in CNV secondary to pathologic myopia (PM-CNV).
- Trial name
- NCT00797992
- Testing
- Injection
- Where
- Brazil
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia
Feasibility of a New Silicone Hydrogel Lens
The objective of this study is to determine the product feasibility of the investigational contact lens (Test) when compared to the currently marketed Acuvue Oasys contact lens (Control) and the Air Optix Aqua contact lens…
- Trial name
- NCT01131130
- Testing
- Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Corneal Astigmatism, Cataract
Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery
What is this study about? This study looks at whether a laser procedure called femtosecond laser-assisted arcuate keratotomy (FSAK) helps people with both cataracts and mild astigmatism see more clearly after cataract surgery.
- Trial name
- NCT07081919
- Testing
- femtosecond laser-assisted arcuate keratotomy (FSAK) combined with standard cataract surgery
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Myopia, Strabismus
A Trial of Bifocals in Myopic Children With Esophoria
To test the hypothesis that correction with bifocal spectacle lenses rather than single-vision lenses will slow the progression of myopia in children with near-point esophoria.
- Conditions
- Myopia, Strabismus, Esophoria
- Trial name
- NCT00000128
- Testing
- Bifocal Spectacle Lenses
- Sponsor
- National Eye Institute (NEI)
Presbyopia
Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle
The purpose of this study was to compare objective clinical measures of visual performance and subjective measures of satisfaction and preference between standard progressive addition lens (PAL) spectacles and a new type of…
- Trial name
- CZV_PAL1 (NCT01234207)
- Testing
- Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Myopia, Myopia Progression
Effect of Diffusion Optics Technology (DOT) Spectacle Lenses on Choroidal Thickness
The objective of the study is to measure the effect of Diffusion Optics Technology (DOT) spectacle lenses on the choroidal thickness and choroidal vascularity index compared to control lenses.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- ASH-2 (NCT05617794)
- Testing
- Diffusion Optics Technology (DOT) Pattern Spectacle Lens, Control Spectacle Lens
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Ametropia
Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use
To evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for 1-month.
- Trial name
- NCT05166902
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States, Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Hyperopia, Farsightedness
Correction of Farsightedness in Children Study
The Correction of Hyperopia In Children Study (CHICS) is a placebo-controlled, randomized, masked investigation of the effect of spectacle correction for moderate amounts of hyperopia on visual function, attention, and reading…
- Trial name
- CHICS (NCT00472212)
- Testing
- Spectacles, Control
- Where
- 4 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Clinical Performance Comparison of Several Different Contact Lenses
The purpose of the study is to evaluate the possible benefits of second generation silicone hydrogel contact lenses.
- Trial name
- NCT00912028
- Testing
- senofilcon A, lotrafilcon B, balafilcon A
- Where
- 11 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia (nearsightedness) is increasing in prevalence throughout the world. It is associated with a risk of potentially blinding complications such as retinal detachment and myopic maculopathy.
- Trial name
- APP (NCT03911271)
- Testing
- 0.1% atropine and 0.01% atropine, 0.01% atropine, 0.9% Sodium-chloride
- Where
- 3 sites in Denmark
- Volunteers
- 97 people
- Sponsor
- Line Kessel
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs
Primary objective of this study is to introduce a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients who underwent pseudophakic presbyopic correction with extended-depth of…
- Trial name
- V(λ)'_EDOF (NCT07077967)
- Testing
- Phacoemulsification with EDOF IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Presbyopia
Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power
To assess postsurgical visual acuity (distant, intermediate, near), refractive errors, contrast sensitivity, visual function and patient satisfaction after implantation of multifocal IOLs of different add power contralaterally.
- Trial name
- NCT02556944
- Testing
- Phacoemulsification with multifocal intraocular lens
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- tae-young chung
Bilateral Cataract, Presbyopia
Symfony/Synergy IOL Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05604781
- Testing
- Symfony & Synergy IOL combination
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Center For Sight
Myopia
A Prospective Study on Clinical Effectiveness After SMILE Versus SMILE Xtra in Myopia
To evaluate the clinical efficacy and refractive stability of SMILE Xtra compared to SMILE in patients with myopia
- Trial name
- NCT06973278
- Testing
- SMILE, SMILE Xtra
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Zhongshan Hospital
Myopia
Daily Disposable Silicone Hydrogel Contact Lens, Stenfilcon A, Clinical Study
Clinical evaluation of stenfilcon A compared with narafilcon A and delefilcon A This is a total 120 subject, randomized, open label, bilateral wear, two week crossover study (each lens for 1 week) evaluating the clinical…
- Trial name
- NCT02637804
- Testing
- stenfilcon A, narafilcon A, delefilcon A
- Volunteers
- 106 people
- Sponsor
- CooperVision, Inc.
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