Clinical trials: Eye--Refractive Errors
Myopia
A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens
Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed lens (control), when worn on a daily basis for 1 month.
- Trial name
- NCT03499067
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of Two Daily Disposable Contact Lenses.
The objective of this clinical study is to evaluate the product performance of SofLens daily disposable contact lenses packaged in the investigational Test solution versus SofLens daily disposable contact lenses packaged in…
- Trial name
- NCT01300065
- Testing
- Experimental- Soflens, Marketed - Soflens
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
The Incidence and Progression of Myopia: Cohort Study
A cohort study on incidence and progression of myopia in a group of medical students
- Trial name
- NCT03244670
- Testing
- Observation study only, no specific intervention
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The purpose of this clinical trial is to assess the clinical performance of LID223194 Multifocal (MF) contact lenses and commercially available Air Optix plus HydraGlyde (AOHG) MF contact lenses.
- Trial name
- NCT05702541
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Alcon Research
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Presbyopia
A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopes implanted in corneal pockets with a delayed or a non-delayed approach.
- Trial name
- NCT03326869
- Testing
- Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Eye Center of North Florida
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
The purpose of this study is to determine whether the prescription determined for a new daily disposable toric contact lens will be a good match to a prescription determined for an existing brand of lens.
- Trial name
- NCT01120782
- Testing
- etafilcon A toric contact lens with new wetting agent, etafilcon A toric contact lens
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types
To evaluate and compare the performance of two monthly replacement multifocal contact lenses in existing wearers.
- Trial name
- NCT06232590
- Testing
- Control Lens (comfilcon A), Test Lens (lehfilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Errors
Clinical Performance of Two Daily Disposable Contact Lenses - Study 1
The purpose of this study is to evaluate end of day (EOD) visual acuity (VA) at distance when wearing Precision1™ contact lenses compared to Acuvue® Moist contact lenses.
- Trial name
- NCT03969290
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- Alcon Research
Glaucoma
Astigmatism Post-trabeculectomy
The aim of this project: 1. Confirming the modification in corneal astigmatism after trabeculectomy with MMC and intracameral administration of bevacizumab. 2. Medium-term follow up (6 months) of the induced corneal astigmatism.
- Trial name
- NCT01711190
- Testing
- trabeculectomy
- Where
- Belgium
- Volunteers
- 52 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Myopia, Progressive
Low Concentration Atropine in the Prevention of Myopia in Children.
This double-blind, randomized controlled clinical study is to evaluate the effectiveness and safety of low concentration atropine in preventing myopia in pre-myopia children, and to explore whether there is a dose effect…
- Trial name
- NCT05939882
- Testing
- low concentration atropine (0.01%), low concentration atropine (0.02%), low concentration atropine (0.04%)
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Refractive Errors
Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial
This is a single-center, randomized, double-blind, controlled study to test whether a new type of eyeglass lens - a "dual-action" lens that combines two technologies (multiple defocus zones and dot diffusion) - can slow the…
- Trial name
- NCT07854457
- Testing
- Dual-Action Myopia-Control Spectacle Lens, Stellest Myopia-Control Spectacle Lens（Highly Aspherical Lenslet Target / HALT Lens）
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Keratoconus, Astigmatism
Corneal Epithelial and Stromal Thickness Distribution in Keratoconus
The purpose of the study was to identify corneal epithelial- and stromal-thickness distribution patterns in keratoconic eyes using spectral-domain-optical coherence tomography (SD-OCT).
- Trial name
- NCT02023619
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- SynsLaser Kirurgi AS
Myopia, Strabismus
A Trial of Bifocals in Myopic Children With Esophoria
To test the hypothesis that correction with bifocal spectacle lenses rather than single-vision lenses will slow the progression of myopia in children with near-point esophoria.
- Conditions
- Myopia, Strabismus, Esophoria
- Trial name
- NCT00000128
- Testing
- Bifocal Spectacle Lenses
- Sponsor
- National Eye Institute (NEI)
Myopia
Patient Reported Outcomes With WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed 6 months post-operatively.
- Trial name
- NCT07087665
- Testing
- Wavelight Plus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OVO LASIK + Lens
Myopia
Evaluating the Efficacy and Safety of Contact Lens Lubricant in Rigid Gas Permeable Corneal Contact Lens Wearers
This trial aims to evaluate the safety and effectiveness of LACRIFRESH OCU-DRY 0.3% OSD, a contact lens lubricant produced by AVIZOR, S.A.
- Trial name
- NCT07091825
- Testing
- LACRIFRESH OCU-DRY 0.3% OSD, Rigid contact lens lubricant
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Avizor SA
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