Clinical trials: Eye--Refractive Errors
Myopia
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
- Trial name
- NCT03516357
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Errors, Ametropia
Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS)
This study aimed to compare refractive measurements using Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic…
- Trial name
- REFRALENS (NCT06668246)
- Testing
- Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic refraction serving as the gold
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Brest
Astigmatism
Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism
The aim of this study is to compare the clinical performance of the Biofinity Toric (comfilcon A) contact lens, versus Air Optix for Astigmatism (lotrafilcon B) over 1 month of daily wear.
- Trial name
- NCT01965288
- Testing
- comfilcon A, lotrafilcon B
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Application of Phototherapeutic Keratectomy Mode to Mark the Axis of Astigmatism
Corneal refractive surgery is an effective way to correct refractive error. Modern corneal refractive surgery for the correction of myopia or hyperopia can achieve or close to the expected goal, but to eliminate astigmatism is…
- Trial name
- NCT06694051
- Testing
- marking
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Stellest Lenses and Low-concentration Atropine Myopia Control Among Children
The prevalence of myopia is increasing globally, especially in Asian countries. 70-80% of the young population suffers from myopia, and almost 20% have high myopia.
- Trial name
- NCT06344429
- Testing
- Stellest Lenses, Stellest Lenses+0.05% atropine, Single vision Lenses+0.05% atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor-Polylite Taiwan Co., Ltd.
Myopia
Ophthalmic Compatibility During Seven Days of Continuous Wear of Silicone Hydrogel Lenses
The purpose of this study is to assess the ophthalmic compatibility of three different silicone hydrogel lenses worn on an overnight basis for six nights.
- Trial name
- QUINCE (NCT00934102)
- Testing
- Narafilcon A contact lens, Lotrafilcon A contact lens, Galyfilcon A contact lens
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- CIBA VISION
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3
It is a common clinical practice to leave small amounts of astigmatism uncorrected in contact lens wearers. Therefore, some drivers who have astigmatism and wear contact lenses may experience blur while driving.
- Trial name
- NCT02950545
- Testing
- Spherical Lenses, Toric Lenses
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Myopia
The Effect of Silicone Hydrogel Contact Lenses on Conjunctival Flora
The primary purpose of this study is to investigate the effect of silicone hydrogel contact lenses on conjunctival flora over a period of 6 months of daily wear.
- Trial name
- NCT00531375
- Testing
- Silicone hydrogel contact lens
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Refractive Error
Clinical Evaluation of the Safety and Efficacy of FID 120947A
The purpose of this study is to evaluate the safety and efficacy of FID 120947A in soft contact lens wearers of Japanese ethnicity.
- Trial name
- NCT02771145
- Testing
- FID 120947A contact lens disinfecting solution, Soft contact lenses (SCL), SCL preservative solution
- Where
- Japan
- Volunteers
- 91 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Accomodation, Biofeedback Training
Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
This study will examine the accommodative behavior in children undergoing myopia control treatments. A subset of children showing reduced accommodation, known to occur in while wearing multifocal soft contact lenses (MFCL) from…
- Conditions
- Accomodation, Biofeedback Training, Myopia
- Trial name
- NCT04807361
- Testing
- Auditory biofeedback traing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Astigmatism, Cataract
Effect of Posterior Corneal Toricity on Refractive Outcome of Pseudophakia
This study is to evaluate the necessity of considering posterior corneal toricity on refractive outcome of patients with cataracts and corneal astigmatism after implantation of intraocular lenses.
- Trial name
- NCT01554761
- Testing
- phacoemulsification, Pentacam (Oculus,Germany)examination
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China Medical University, China
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia
Daily Disposable Comparison Study
The objective of the study is to compare the overall subjective preference between two Daily Disposable hydrogel lenses when refitted into a third hydrogel lens.
- Trial name
- NCT02094677
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Presbyopia
Comparing the Performance of 1 Day Multifocal Contact Lenses
The objective of the study was to compare the lens handling and performance of Lens A to habitually worn multifocal contact lenses and to the competitor Lens B.
- Trial name
- NCT04449263
- Testing
- Lens A, Lens B, Habitual Lenses
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Contact Lens Complication, Astigmatism
T30 for Astigmatism in Digital Device Users
This study aims to determine if Total30 lenses for astigmatism can be successfully fit in participants who are heavy digital device users.
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- T30FA (NCT06266728)
- Testing
- Total30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Myopia, Progressive, Atropine Allergy
Eye Drops Study for Myopia Control in Schoolchildren
The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life.
- Trial name
- NCT03402100
- Testing
- eye drops
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Astigmatism
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in…
- Trial name
- NCT07140653
- Testing
- Femto arcs, Light Adjustable Lens (LAL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Center For Sight
Myopia
Effect of Low-level Red-light on Ultra-high Myopia
100 eyes of ultra-high myopia were treated with daily low-level red-light. The age of children ranged from 3 to 16.3 years. The follow-up duration was one year.
- Trial name
- NCT06738095
- Testing
- daily low-level red-light
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Beijing Tongren Hospital
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