Clinical trials: Eyelid Droop
Blepharoptosis, Lagophthalmos
Magnetic Correction of Eye Lid Paralysis
Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of…
- Conditions
- Blepharoptosis, Lagophthalmos, Facial Paralysis
- Trial name
- NCT02988856
- Testing
- Magnetic lid system
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Kevin Houston
Dacryocystorhinostomy, Ectropion
PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery
The aim of this study is to show that the performance of Novosyn® Quick suture material is comparable with standard suture material used in Ophthalmic surgery.
- Conditions
- Dacryocystorhinostomy, Ectropion, Entropion, Ptosis
- Trial name
- OPHTHALNOQ (NCT02761083)
- Testing
- Novosyn® Quick, Vicryl® Rapid
- Where
- Spain
- Sponsor
- Aesculap AG
Blepharoptosis, Device Usability
A Feedback-enabled Magnetic Device for Temporary Management of Blepharoptosis
To develop a feedback-enabled magnetic device for management of blepharoptosis and evaluate its efficacy and safety, including the gain of palpebral fissure height, visual field obstruction, blurred vision, foreign body sensation…
- Trial name
- NCT03812016
- Testing
- Feedback-enabled magnetic device
- Where
- 2 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- E-DA Hospital
Ptosis
Levator Muscle Strength Evaluation
The purpose of this study is to assess a new technique of measurement for the levator muscle. this measurement may be applied during a clinical evaluation of eyelid malposition.
- Trial name
- NCT02226016
- Testing
- FG-5000A
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Blepharoptosis
Custom Print Megnetic Levator Prosthesis Pilot Comparison
Study the device feasibility of non-surgical treatment for blepharoptosis (inability to open the eyelid) consisting of a biocompatible magnetic element adhered to the upper eyelid and a second magnet above the eye on a custom…
- Trial name
- NCT04807855
- Testing
- The cMLP device
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Skelmet Inc
Eyelid Droop
The Effect of Lumify™ Eyedrops on Eyelid Position
The purpose of the research is to see if Lumify™ has an effect on eyelid position.
- Trial name
- NCT03782701
- Testing
- Brimonidine tartrate ophthalmic solution 0.025%, Sterile balanced saline solution
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acquired Blepharoptosis
Study of the Safety and Efficacy of RVL-1201 in the Treatment of Acquired Blepharoptosis
This is a Phase 3 study is to evaluate the safety and efficacy of RVL-1201 Ophthalmic Solution in the treatment of acquired blepharoptosis (ptosis) and to assess the safety and comfort of RVL-1201 Ophthalmic Solution for an…
- Trial name
- NCT02436759
- Testing
- RVL-1201
- Where
- 14 sites in United States
- Volunteers
- 140 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Blepharoptosis, Lagophthalmos
NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy
Traumatic brain injury, stroke and other neurological conditions may result in weakness of the muscles that either open or close the eye.
- Trial name
- EyeStim (NCT03239418)
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brooks Rehabilitation
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).
- Trial name
- NCT02230761
- Testing
- XOPH5 Ointment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Topokine Therapeutics, Inc.
Blepharoptosis, Ecchymosis; Eyelid
Fibrin Sealant in Eyelid Surgery
This study is looking at the effect of Tisseel in eyelid surgery. Fibrin sealants (Tisseel) cause there to be less bleeding during surgery. Surgeons have used Tisseel for over two decades to reduce bruising.
- Trial name
- NCT05358977
- Testing
- Tisseel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Ptosis, Macular Degeneration
Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues
The purpose of this study is to compare the results of vision tests that are algorithmically derived and delivered through a virtual reality headset with those delivered through the existing technology standards (eg.
- Conditions
- Ptosis, Macular Degeneration, Ametropia
- Trial name
- RTS1 (NCT04714424)
- Testing
- Virtual Reality Headset
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Blepharoptosis
Study of Safety and Efficacy of RVL-1201 in the Treatment of Blepharoptosis
Phase 3 study to evaluate the safety and efficacy of treatment with RVL-1201 compared to placebo for treatment of blepharoptosis. Eligible subjects will be randomized to one of 2 treatment arms.
- Trial name
- NCT03565887
- Testing
- RVL-1201, Vehicle ophthalmic solution
- Where
- 36 sites in United States
- Volunteers
- 164 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Blepharoptosis
Liquid Bandage (2-Octyl-Cyanoacrylate) in Upper Lid Blepharoplasty
The aim of this randomized and masked prospective trial is to compare the effectiveness of Liquid Bandage (Octyl-2-Cyanoacrylate) and 6/0 nylon suture as a wound closure device in upper lid blepharoplasty surgery.
- Trial name
- NCT00816270
- Testing
- Bilateral Upper eyelid blepharoplasty
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
Eyelid Movement Disorders, Eyelid Ptosis Congenital
Müller's Muscle as a New Proprioceptive Organ
Objectives: Upper eyelid retraction was believed to be maintained solely by voluntary contraction of the levator palpebrae superioris (LPS) and frontalis muscles, together with involuntary contraction of the sympathetically…
- Trial name
- NCT03396627
- Testing
- pathological examination
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Blepharoptosis, Blepharochalasis, Superior
Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries
The aim of the study: Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries. Study design: an interventional study that will be conducted at the ophthalmology department, Meir hospital…
- Conditions
- Blepharoptosis, Blepharochalasis, Superior, Ectropion, Entropion
- Trial name
- NCT02638610
- Testing
- Cochet-Bonnet aesthesiometer
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Glaucoma Eye, Glaucoma
Comparison of Fixation Suture Type in Glaucoma Surgery
The aim of the study is to compare the effectiveness and safety of two types of intraoperative eye fixation: for the superior rectus muscle and traction suture in the peripheral cornea.
- Trial name
- NCT03797846
- Testing
- combined glaucoma surgery
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Glaucoma, Glaucoma, Open-Angle
The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients
Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma; Drugs, Droopy Eyelid
- Trial name
- NCT04007276
- Testing
- brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tulane University
Eyelid Diseases, Eyelid Droop
Spacer Graft Study
To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)
- Trial name
- NCT04140734
- Testing
- Spacer Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute