Clinical trials: Eyelid Tumor
Chalazion
Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a Chalazion
The purpose of this study is to evaluate the efficacy and safety of SUN-131 1.5% TDS as compared with placebo TDS in the treatment of chalazion based on the proportion of subjects that have complete response.
- Trial name
- NCT02338648
- Testing
- SUN-131 1.5% TDS
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Senju USA, Inc.
Dacryocystorhinostomy, Ectropion
PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery
The aim of this study is to show that the performance of Novosyn® Quick suture material is comparable with standard suture material used in Ophthalmic surgery.
- Conditions
- Dacryocystorhinostomy, Ectropion, Entropion, Ptosis
- Trial name
- OPHTHALNOQ (NCT02761083)
- Testing
- Novosyn® Quick, Vicryl® Rapid
- Where
- Spain
- Sponsor
- Aesculap AG
Melanoma (Skin), Melanoma in Situ
Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence Algorithm
The purpose of this study is to establish a standardized process for obtaining digital pathological image information of ocular tumors; use modern pathological techniques to obtain the co-expression information of multiple…
- Conditions
- Melanoma (Skin), Melanoma in Situ, Nevus Eye, Sebaceous Gland Carcinoma of the Eyelid
- Trial name
- NCT04695015
- Volunteers
- 100 people
- Sponsor
- Peking University
Ectropion, Skin Neoplasms
5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts
Full thickness skin grafts are an essential tool in surgery around the eyelids for reconstruction or rehabilitation following injury or surgery.
- Trial name
- NCT02705352
- Testing
- 5-Fluorouracil, Normal saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Chalazia, Chalazion
Intralesional Tetracycline Injection in the Treatment of Chalazia
The investigators propose a study to investigate the role of tetracycline injection into chalazia versus observation alone. The investigators hypothesize tetracycline injection will result in a significant decrease in lesion size…
- Trial name
- TET (NCT01763437)
- Testing
- Tetracycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Chalazion
Safety and Efficacy Study of SUN-131 Transdermal System (TDS) as Compared to Placebo TDS in Patients With a Chalazion
This protocol for SUN-131 1.5% TDS is developed for the treatment of chalazion. SUN-131 1.5% TDS is designed for local delivery of a corticosteroid, to the upper or lower eyelid.
- Trial name
- SUNRISE (NCT03248440)
- Testing
- SUN-131 1.5% TDS
- Where
- 65 sites in United States
- Volunteers
- 263 people
- Sponsor
- Senju USA, Inc.
Moderate and Severe Meibomiang Gland Dysfunction (Stage 3 or Stage 4 Meibomiang Gland Dysfunction)
Changes of Keratometric Value and Ocular Aberration After Treatment of Meibomian Gland Dysfunction
Ocular aberration may play a role in determining optical quality. Recently performed study reported that ocular aberration of preocular tear film would be important factor in not only diagnosing the dry eye but also determining…
- Trial name
- NCT01692665
- Sponsor
- Yonsei University
Reconstructive Surgical Procedure
Reconstruction of Upper Eyelid With a Newly Modified Cutler-Beard Technique With Tarsoconjunctival Graf
To study the results of a modified Cutler-Beard technique , using a contralateral tarsoconjunctival graft, in patients who underwent excision of large malignant tumors of the upper eyelid
- Trial name
- NCT03712995
- Testing
- 'Cutler-Beard modified with graft'
- Volunteers
- 10 people
- Sponsor
- Hospital Universitario 12 de Octubre
Skin Cancer
Comparative Retrospective Analysis of Skin Tumors of the Eyelids and Face in 2 Brussels University Hospitals Over 5 Years in Dermatology or Ophthalmology
Skin cancers are the most common of all cancers. Their incidence has increased sharply over the decades.This increase in incidence partly reflects an aging population and behavioral patterns such as repeated exposure to the sun.
- Trial name
- NCT04886908
- Testing
- Data extraction from medical files
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- Brugmann University Hospital
Incomplete Closure of Lid, Parotis Tumor
External Lid Loading for the Temporary Treatment of the Paresis of the M. Orbicularis Oculi: a Clinical Note
The note re-introduces the external lid loading with the help of a lead weight for the temporary treatment of lagophthalmos. Although simple and effective, the technique is rarely used.Instead of wearing a monoculus, the patient…
- Conditions
- Incomplete Closure of Lid, Parotis Tumor, m. Orbicularis Oculi Paresis
- Trial name
- NCT01274689
- Testing
- individually tailored lead weight
- Where
- Germany
- Volunteers
- 152 people
- Sponsor
- Charite University, Berlin, Germany
Basal Cell Cancer, Eyelid Tumor
Dose-Modulated Sonidegib Therapy for Periocular Basal Cell Carcinoma
The goal of this clinical trial is to evaluate the safety, tolerability, and clinical outcomes of a dose-modulation strategy of Sonidegib in adult patients with locally advanced periocular basal cell carcinoma (laBCC) who are not…
- Conditions
- Basal Cell Cancer, Eyelid Tumor, Basal Cell Carcinoma (BCC), Basal Cell Carcinoma of the Head and Neck
- Trial name
- BCC-Sonidegib (NCT07068568)
- Testing
- Sonidegib
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Federico II University
Basal Cell Carcinoma, Eye Diseases
BCC Excision Revisited
To readdress basal cell carcinoma (BCC) in the periocular region to prove histologically controlled surgical treatment efficacy and to identify high-risk characteristics.
- Conditions
- Basal Cell Carcinoma, Eye Diseases, Eye Cancer
- Trial name
- NCT05853315
- Testing
- Surgery
- Where
- Austria
- Volunteers
- 451 people
- Sponsor
- Medical University of Vienna
Pediatric Chalazia
Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia
Participants enrolled into the study will be prescribed twice daily warm compresses for 8 weeks and randomly allocated (1:1:1) to receive either 1) Oral omega-3 supplementation and standard eyelid cleanser, 2) Anti-Demodex eyelid…
- Trial name
- CH01 (NCT07496515)
- Testing
- Omega-3 supplement, Warm compress, Standard eyelid cleanser
- Volunteers
- 168 people
- Sponsor
- Jaeb Center for Health Research
Carcinomas (Including Squamous Cell and Adenocarcinoma)
Epidemiological, Clinicopathological, and Surgical Characteristics of Eyelid Carcinomas
Twenty patients were included, comprising 11 women (55%) and 9 men (45%), with a mean age of 63.1 years. Chronic sun exposure was identified in 18 patients (90%).
- Trial name
- epidemiology (NCT07723365)
- Where
- Morocco
- Volunteers
- 20 people
- Sponsor
- Mohammed VI University Hospital
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07405138
- Testing
- Active IPL
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lumenis Be Ltd.
Chalazion
Probiotics for Treatment of Chalazion in Adults
There is growing evidence encouraging probiotics use in several diseases. The aim of the investigator's study is to define the possible beneficial impact of probiotics on adults suffering from chalazia.
- Trial name
- NCT04342507
- Testing
- conservative treatment, probiotics
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Molise
Chalazion
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.
- Trial name
- CTS (NCT02025023)
- Testing
- 5-fluorouracil Injection, Triamcinolone Acetonide, Incision and Curettage
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07039461
- Testing
- OptiLIGHT
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Eye Disease, Melanoma
Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma
The goal of this clinical research study is to find the sentinel lymph node (SLN) (s) and biopsy it (them) to see if the patient has small or low volume metastatic disease that would otherwise have been missed.
- Trial name
- NCT00386906
- Testing
- Sentinel Lymph Node Mapping and Biopsy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- M.D. Anderson Cancer Center
Meige Syndrome, Meigs Syndrome
A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome
In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral…
- Conditions
- Meige Syndrome, Meigs Syndrome, Meige Disease, Meig Syndrome
- Trial name
- NCT04618887
- Testing
- pallidotomy, deep brain stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital