Clinical trials: Eyes With Glaucoma
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Optical Coherence Tomography Findings Associated With the Glaucoma-periodontitis Stage
The aim of this observational study is to investigate the relationship between the stage of periodontal disease and retinal layer thicknesses in glaucoma patients using optical coherence tomography (OCT).
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Periodontitis
- Trial name
- NCT07853469
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Glaucoma
Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
The goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years.
- Trial name
- EyeQ (NCT07364929)
- Testing
- Full-spectrum light exposure, Standard indoor light exposure (Control)
- Where
- 2 sites in Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Primary Open- Angle Glaucoma
Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle Glaucoma
This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele.Primary open-angle glaucoma patients and age-matched people in the Han population…
- Trial name
- NCT02805231
- Testing
- Vitamin D receptor polymorphic analysis
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lv Yingjuan
Corneal Ectasia, Corneal Disease
Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics
The purpose of this study is the investigation of biomechanical properties of the cornea using computer-aided data analysis. Currently, it is known that keratoconus and glaucoma are ocular disease that are associated with…
- Conditions
- Corneal Ectasia, Corneal Disease, Corneal Astigmatism, Keratoconus
- Trial name
- EyeTwin (NCT04475900)
- Testing
- Corneal biomechanics (Corvis ST, Oculus, Wetzlar, Germany), Corneal topography and tomography (Pentacam, Oculus, Wetzlar, Germany), Optic nerve head measurement
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Primary Open Angle Glaucoma (POAG)
Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
The purpose of this study is to evaluate the safety and efficacy of the iStent medical device that is implanted into the eye and designed to reduce eye pressure in patients with your condition.
- Trial name
- NCT01252849
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Glaucoma, Open-Angle
Visual Field Defect Estimation Using Sequentially Optimized Reconstruction Strategy on Healthy and Glaucoma Subjects
Perimetry is a well-established method that is used to measure the visual field functions of humans. Commercially available products, such as the OCTOPUS 900 (Haag-Streit AG, Koeniz, Switzerland), are commonly used for assessing…
- Trial name
- NCT03325751
- Testing
- Visual field testing
- Where
- Switzerland
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Glaucoma
Glaucoma Screening With Artificial Intelligence
This randomized clinical trial aims to compare the diagnostic performance of two AI-enabled screening strategies - ROTA (RNFL optical texture analysis) assessment versus optic disc photography - in detecting glaucoma within a…
- Trial name
- NCT06012058
- Testing
- ROTA assessment by AI, Optic disc assessment by AI
- Where
- 2 sites in Hong Kong
- Volunteers
- 3,175 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Glaucoma, Cataract
Phacotrabeculectomy With Collagen Matrix Implant (Ologen®) Versus Mitomycin C
1. Study objective: To assess the efficacy and safety of collagen matrix implant (Ologen®; OLO) in phacotrabeculectomy and to compare with mitomycin C (MMC) augmented phacotrabeculectomy. 2.
- Conditions
- Glaucoma, Cataract, Wound Heal
- Trial name
- NCT03506542
- Testing
- Ologen, Phacotrabeculectomy, Mitomycin C
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Glaucoma
Evaluation of Visual Training System in Patients With Glaucoma
This study intends to conduct visual function examinations and follow-ups on two groups of glaucoma patients, one receiving visual perceptual training and the other serving as a control without training.
- Trial name
- NCT06433102
- Testing
- Visual perceptual training based on the lateral masking paradigm
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy Volunteers
Bimatoprost Ocular Insert Pharmacokinetic Study
The Bimatoprost Ocular Insert is intended to provide sustained delivery of bimatoprost to the ocular surface to lower the intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT02444767
- Testing
- 13mg Bimatoprost Ocular Insert
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- ForSight Vision5, Inc.
Normal Tension Glaucoma
Effect of Netarsudil vs Brimonidine in NTG Patients on Latanoprost
A randomized, multicenter, investigator-masked prospective study of NTG patients currently on latanoprost 0.005% monotherapy, to study the effect of IOP change with the introduction of netarsudil 0.02% vs brimonidine 0.1%.
- Trial name
- NCT06449352
- Testing
- Netarsudil, Brimonidine
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Westlake Eye Specialists
Glaucoma, Myopia
Corrected Measurement of the Retinal Nerve Fiber Layer Thickness by Optic Disc Configuration With the Cirrus HD OCT
Because the measurement of the retinal nerve fiber layer thickness is very sensitive to the position of measurement, it may be incorrect in patients with the tilted disc.
- Trial name
- NCT00741130
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma
Effect of Age on Latanoprost 0.005% in Patients With Glaucoma
Latanoprost is a commonly used treatment for glaucoma. Because of its mechanism of action, it is plausible that the age of a patient using the medication may affect its efficacy and time of onset.
- Trial name
- NCT00224289
- Testing
- Latanoprost 0.005%
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University
Dry Eye Disease
Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z®
The purpose of this study is to determine if there is a difference in the ocular signs and symptoms of subjects' eyes using Xalatan® 0.005% versus Travatan Z® 0.004% based on the outcome of subject assessment and clinical…
- Trial name
- NCT00799682
- Testing
- Xalatan, Travatan Z
- Where
- 5 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Glaucoma, Open-Angle
Lamina Cribrosa Depth Change With Change in Eye Pressure
This is a study of the compliance of the lamina cribrosa with change in eye pressure.
- Trial name
- NCT03267849
- Testing
- wearing swimming goggles or having laser suturelysis
- Where
- United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University