Clinical trials: FMT
Physical Abilities, FMT
Assessing the Potential Role of the Gut Microbiome in Modulating Physical Abilities in Humans
The intestinal microbiome is a microbial system that is influenced by host genetics and environmental exposures such as nutrition, stress and medications.
- Trial name
- NCT05024188
- Testing
- Antibiotics, Autologous Fecal Microbiota Transplantation, Cellules Pills
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Autoimmune Thyroid Disease, Type 2 Diabetes Mellitus (T2DM)
Fecal Microbiota Transplantation for Type 2 Diabetes Mellitus and Hashimoto's Thyroiditis
The goal of this clinical trial is to learn if fecal microbiota transplantation (FMT) can improve metabolic control and immune function in adults with both type 2 diabetes and Hashimoto's thyroiditis (an autoimmune thyroid…
- Conditions
- Autoimmune Thyroid Disease, Type 2 Diabetes Mellitus (T2DM), FMT
- Trial name
- NCT07733232
- Testing
- Fecal microbiota transplantation oral capsules
- Volunteers
- 38 people
- Sponsor
- Shen Xujun
Alopecia Areata, Fecal Microbiota Transplantation (FMT)
The Role of Gut and Skin Microbiota in Alopecia Areata
The goal of this clinical trial is to learn if fecal microbiota transplantation (FMT) works to treat alopecia areata in adults. It will also learn about the safety of FMT.
- Conditions
- Alopecia Areata, Fecal Microbiota Transplantation (FMT), T Cell Subsets, Microbiome
- Trial name
- RGSM-AA-ICS (NCT07705217)
- Testing
- Fecal Microbial Transplant Enema
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- Polyclinic GrandMed
Diabetes Mellitus Type 2, Fecal Microbiota Transplantation (FMT)
Fecal Microbiota Transplantation Intervention on Microbiota Composition and Insulin Sensitivity in Diabetes
The purpose of the trial is to investigate the effect of fecal microbiota transplantation versus placebo on glycemic metabolism and gut microbiota composition in people with type 2 diabetes.
- Conditions
- Diabetes Mellitus Type 2, Fecal Microbiota Transplantation (FMT), Oral Glucose Tolerance Test, Continuous Glucose Monitoring
- Trial name
- FeMIC (NCT07375797)
- Testing
- Fecal Microbial Transplantation
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Central Jutland Regional Hospital
Hidradenitis Suppurativa (HS), Fecal Microbiota Transplantation (FMT)
FEcal tranSplantation in HidradeniTIs suppuratiVA : a piLot Study
The medical and surgical treatment of hidradenitis suppurativa (HS) remains difficult to date. The search for new therapies for HS is a major challenge.
- Trial name
- FESTIVAL (NCT07668713)
- Testing
- Fecal microbiota transplantation (FMT)
- Where
- 7 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Fecal Microbiota Transplantation (FMT)
Stool Transplant to Control Treatment-related Diarrhea
This study will test the safety, effectiveness, and feasibility of a treatment called fecal microbiota transplantation (FMT) to reduce the symptoms of ICI-related diarrhea.
- Trial name
- NCT04883762
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Clostridioides Difficile Infection Recurrence, FMT
FMT Capsules for rCDI
Double blind RCT study of tretment of recurrent Clostridioides difficile infection by FMT capsules.
- Trial name
- FMT CAP CDI (NCT07458984)
- Testing
- Healthy donor stool
- Where
- Finland
- Volunteers
- 76 people
- Sponsor
- Helsinki University Central Hospital
Alzheimer s Disease, Faecal Microbiota Transplantation (FMT)
Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study
The goal of this study is to assess the feasibility and safety of faecal microbiota transplantation for Alzheimer's disease.
- Trial name
- AD-FMT (NCT07332260)
- Testing
- Biological: Preprocessed thawed donor FMT
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- University Hospital of North Norway
Cachexia; Cancer, Fecal Microbiota Transplantation (FMT)
Intestinal Microbiota Transplantation for Treating Advanced Tumor Cachexia
This project is a prospective, multicenter, single-arm, phase II clinical study aimed at evaluating the efficacy and safety of fecal microbiota transplantation (FMT) in treating advanced tumor cachexia.
- Trial name
- FMT-CACH (NCT07533227)
- Testing
- FMT capsule
- Volunteers
- 66 people
- Sponsor
- Hua Jiang
Constipation - Functional, Fecal Microbiota Transplantation (FMT)
The Safety and Efficacy of Fecal Microbiota Transplantation Combined With Nutritional Intervention in the Treatment of Functional Constipation：a Pilot Study
Chronic constipation is a common gastrointestinal disease with a global prevalence of about 15%, significantly affecting daily life and quality of life.
- Conditions
- Constipation - Functional, Fecal Microbiota Transplantation (FMT), Chronic Constipation
- Trial name
- NCT07387952
- Testing
- FMT
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Peking Union Medical College Hospital
Fecal Microbiota Transplantation (FMT), Gastrointestinal Neoplasms
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
The goal of this clinical trial is to learn if fecal microbiota transplantation can treat in Gastrointestinal cancer patients with chemotherapy / targeted gastrointestinal symptoms.
- Conditions
- Fecal Microbiota Transplantation (FMT), Gastrointestinal Neoplasms, Antineoplastic Agents, Drug-related Side Effects and Adverse Reactions
- Trial name
- NCT07319364
- Testing
- Fecal microbiota transplantation (FMT)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Clostridioides Difficile Infection, Clostridioides Difficile Infection Recurrence
STOP-CDI: Efficacy of Fecal Microbiota Transplantation vs Fidaxomicin vs Vancomycin in Treating and Preventing Relapse of Clostridioides Difficile Infection
The STOP-CDI study is a multicenter, randomized, open-label, three-arm clinical trial comparing the efficacy of fecal microbiota transplantation (FMT) preceded by vancomycin, fidaxomicin monotherapy, and standard-of-care…
- Conditions
- Clostridioides Difficile Infection, Clostridioides Difficile Infection Recurrence, Fecal Microbiota Transplantation (FMT), Comparative Effectiveness of CDI Treatments
- Trial name
- STOP-CDI (NCT07120490)
- Testing
- FMT (fecal microbiota transplantation), Fidaxomicin, Vancomycin (VAN) treatment
- Volunteers
- 424 people
- Sponsor
- Medical University of Warsaw
Autism Spectrum Disorder, Fecal Microbiota Transplantation (FMT)
Open Label Phase IIa Trial Evaluating the Effect and Safety of Transplantation of Fecal Microbiota in Children With Autism Spectrum Disorders and Gastrointestinal Symptoms
Autism Spectrum Disorders (ASD), affect approximately 1% of the general population and are characterized by impairments in social communication associated with repetitive/stereotyped behaviors.
- Trial name
- FELICITA (NCT07105267)
- Testing
- FMT Protocol
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitis, Type 1 Diabetes (T1D)
Faecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus
SUMMARY Rationale: The(small) intestinal microbiota composition has been implicated to play an important role in (human) metabolism, as well as autoimmune diseases such as type 1 diabetes mellitus.
- Conditions
- Type 1 Diabetes Mellitis, Type 1 Diabetes (T1D), Fecal Microbiota Therapy (FMT)
- Trial name
- FACT-T1D (NCT07083882)
- Testing
- freezedried autologous encapsulated fecal microbiota transplantation
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Irritable Bowel Syndrome, Diarrhea-Predominant (IBS-D), Recurrent Clostridioides Difficile Infection (rCDI)
A Flexible Clinical Trial to Test if Freeze-dried Fecal Microbiota Therapy Helps Treat Diarrhea-predominant Irritable Bowel Syndrome or Prevent Recurring C. Difficile Infections.
The goal of this clinical trial is to learn if oral lyophilized fecal microbiota therapy (ORAL-LYO-FMT) helps treat diarrhea-predominant irritable bowel syndrome (IBS-D) and prevent the recurrence of Clostridioides difficile…
- Conditions
- Irritable Bowel Syndrome, Diarrhea-Predominant (IBS-D), Recurrent Clostridioides Difficile Infection (rCDI), Fecal Microbiota Therapy (FMT), Irritable Bowel Syndrome (IBS)
- Trial name
- ORAL-LYO-FMT (NCT06948461)
- Testing
- ORAL-LYO-FMT
- Volunteers
- 63 people
- Sponsor
- PharmaPlanter Technologies Inc
Faecal Microbiota Transplantation (FMT), Diabetes Mellitus, Type 1
Faecal Microbiota Transplantation for Patients With Diabetes Mellitus Type 1 and Severe Gastrointestinal Neuropathy
A randomised, double-blinded and placebo-controlled intervention study. The study aim to evaluate the feasibility, safety and pilot-efficacy of faecal microbiota transplantation as a treatment of severe gastrointestinal…
- Conditions
- Faecal Microbiota Transplantation (FMT), Diabetes Mellitus, Type 1, Gastrointestinal Neuropathy
- Trial name
- Fadigas (NCT04749030)
- Testing
- Faecal microbiota transplantation (FMT) capsules
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Non Alcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease
Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis
The goal of this clinical trial is to investigate the therapeutic potential of A. soehngenii and pasteurized A. muciniphila combined with B. animalis subsp.
- Conditions
- Non Alcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease, Fecal Microbiota Transplantation, FMT
- Trial name
- SYNCH (NCT05821010)
- Testing
- Lyophilized fecal microbiota transplantation capsules, A. soehngenii, Pasteurized A. muciniphila
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ulcerative Colitis, FMT
Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC)
The researchers intend to prospectively study the safety, clinical efficacy and microbial outcomes in patients with recently diagnosed UC with FMT capsule therapy derived from pre-defined donors.
- Conditions
- Ulcerative Colitis, FMT, Fecal Microbiota Transplant
- Trial name
- REFOCUS (NCT04968951)
- Testing
- Metronidazole, Vancomycin, Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ari M Grinspan
Clostridium Difficile Infection, Recurrent Clostridium Difficile Infection
Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile Infection
This is an open-label study evaluating the safety and efficacy of CP101 treatment in 1) Subjects in CDI-001 who had a CDI recurrence within 8 weeks of receiving CP101 or placebo; OR 2) adults with recurrent CDI who are eligible…
- Conditions
- Clostridium Difficile Infection, Recurrent Clostridium Difficile Infection, C. Diff, CDI
- Trial name
- PRISM-EXT (NCT03497806)
- Testing
- CP101
- Where
- 57 sites in United States, Canada
- Volunteers
- 132 people
- Sponsor
- Finch Research and Development LLC.
Obesity, Weight Loss
The Role of Microbiome in Recurrent Obesity
This past century witnessed a significant increase in the prevalence of obesity, when since 1980 worldwide obesity has more than doubled.
- Conditions
- Obesity, Weight Loss, FMT
- Trial name
- NCT05002153
- Testing
- Fecal microbiota transplantation (FMT)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assaf Harofeh MC