Clinical trials: FNA
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
A pilot study to assess the effects of six months of letrozole on breast tissue risk markers in postmenopausal women on hormone replacement therapy at high risk of developing breast cancer.
- Trial name
- NCT00291135
- Testing
- letrozole
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carol Fabian, MD
Pancreas, Mass Lesion
Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies
This is a randomized study that will enroll patients scheduled for an endoscopic ultrasound biopsy of a pancreas lesion to be in the heparin or saline group during the procedure.
- Trial name
- NCT04764396
- Testing
- Heparin will be used for needle priming (BD PosiFlush™ Pre-Filled Heparin Lock Flush Syringe), Saline
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Breast Cancer
Feasibility of Ultrasound Microbubble Contrast-Enhanced (CEUS) Sentinel Lymph Node Imaging With Guided Biopsy in Breast Cancer Patients
The goal of this clinical research is to learn if an ultrasound contrast agent called OPTISON (perflutren protein type A) is effective in finding sentinel lymph nodes before surgery.
- Trial name
- NCT02321527
- Testing
- Perflutren Protein-Type A Microspheres Injectable Suspension, Contrast-Enhanced Ultrasound (CEUS), Biopsy + Radioactive Seed Placement
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- M.D. Anderson Cancer Center
EUS Guided Biopsy
SharkCore Versus Acquire FNB
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been established as an effective technique for sampling tissue inside and around the gastrointestinal tract, including the pancreas, liver, lymph nodes, and…
- Trial name
- NCT03672032
- Testing
- Fork-tip Needle, Franseen Needle
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Henning Gerke
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Breast Atypical Ductal Hyperplasia, Breast Ductal Carcinoma In Situ
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
This phase III trial studies how well metformin hydrochloride works compared to placebo in preventing breast cancer in patients with atypical hyperplasia or in situ breast cancer.
- Conditions
- Breast Atypical Ductal Hyperplasia, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In Situ
- Trial name
- NCT01905046
- Testing
- metformin hydrochloride
- Where
- 27 sites in United States
- Volunteers
- 86 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study
This research is being done to investigate if a new technique to biopsy the pancreas will lead to a larger amount tissue material that can be analyzed.
- Trial name
- NCT02116322
- Testing
- EUS-FNA with Corkscrew technique, Expect 19 G Flex needle
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Pancreatic Cancer, Lymphadenopathy
Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle
Endoscopic ultrasound (EUS) is paramount in the diagnosis and evaluation of cancers involving the gastrointestinal tract. EUS allows for the acquisition of cellular (fine needle aspirate - FNA) or tissue biopsy (fine needle…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
- Trial name
- MUCIN (NCT01769248)
- Testing
- Fine needle aspiration, Fine needle biopsy
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
Cancer of Pancreas, Pancreatic Neoplasm
Trial Comparing 19 and 25-gauge EUS-FNA Needles
This study compares the 19G and 25G needles for procuring tissue samples from the pancreas during Endoscopic Ultrasound (EUS) procedures.
- Trial name
- EUS-FNA (NCT01677312)
- Testing
- Pancreatic Biopsy, Histological Samples
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- AdventHealth
Solid Pancreatic Mass Lesions, Malignant Neoplasm of Pancreas
Comparison of a Novel 22-gauge Core Biopsy Needle
The goal of this clinical research study is to compare the performance of a newly available needle with reverse bevel design (called the EchoTip® Procore™ needle) with standard needles to see which needle gives better diagnostic…
- Trial name
- NCT01598194
- Testing
- Novel 22-gauge Core Biopsy Needle + Standard Biopsy Needle
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Fine Needle Aspiration, Pancreatic Mass
EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without…
- Trial name
- NCT03485924
- Testing
- EUS-FNA with ROSE, EUS-FNB without ROSE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods
EUS-guided Fine Needle Aspiration (FNA) With and Without the Use of a Stylet
The purpose of this study is to determine that there is no difference in final diagnosis of FNA specimens without a stylet, compared to using a stylet, when examined by a skilled cytopathologist.
- Conditions
- Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods, Endosonography
- Trial name
- NCT01316614
- Testing
- FNA with and without a stylet
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Washington University School of Medicine
Pancreatic Neoplasm
22G FNA Needle vs. 22G ProCore Needle
The aim of this research study is to identify the best needle for performing biopsy during EUS procedures. There are two types of needles for performing biopsy: A FNA needle that provides a small sample of tissue for analysis and…
- Trial name
- NCT01394159
- Testing
- 22G ProCore biopsy needle, 22G standard FNA needle
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- AdventHealth
Pancreatic Masses, Lymph Nodes
Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 25G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device.
- Trial name
- ASPRO (NCT02167074)
- Testing
- 25G FNA needle, 20G ProCore FNB needle
- Where
- 13 sites in United States, Australia and 8 more
- Volunteers
- 615 people
- Sponsor
- Foundation for Liver Research
Pancreatic Solid Lesions, Pancreatic Mass
Comparison of Two Needle Aspiration Techniques for Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) in Solid Pancreatic Lesions
The aim of this study is to compare Endoscopic Ultrasound and Fine Needle Aspirate with a standard 22-gauge needle using either "standard-suction" or "capillary suction" methods for solid pancreatic lesions.
- Trial name
- NCT01936467
- Testing
- Standard technique EUS-FNA, Capillary suction technique for EUS FNA
- Where
- 2 sites in United States
- Volunteers
- 121 people
- Sponsor
- Johns Hopkins University
Hepatitis B
A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B
Hepatitis B virus (HBV) infection, especially chronic, is a significant worldwide medical problem. This is an exploratory study of the therapeutic mechanism of GSK3228836 in participants with chronic hepatitis B (CHB) on stable…
- Trial name
- B-Fine (NCT04544956)
- Testing
- GSK3228836, Nucleos(t)ide therapy
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Hepatitis C
Intrahepatic HCV RNA and Telaprevir Kinetics in Hepatitis C Virus (HCV)
The purpose of this study is to determine the decline of virus in the blood and liver in patients treated with telaprevir, pegylated interferon and ribavirin.
- Trial name
- NCT00892697
- Testing
- Telaprevir, Peginterferon alfa-2a, Ribavirin
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer
LY353381 in Preventing Breast Cancer in Women With Hyperplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of LY353381 may be an effective way to prevent the development of breast cancer in women who have…
- Trial name
- NCT00005879
- Testing
- arzoxifene
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Healthy, Male Infertility
HOP-2A - Intratesticular Hormone Levels
The purpose of this investigational study is to find out what hormones are present in healthy male testicles using fine needle aspiration.
- Conditions
- Healthy, Male Infertility, Prostate Disease
- Trial name
- HOP-2A (NCT00756561)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington