Clinical trials: FRENCH STUDY
Parkinson Disease
French Parkinson's Disease Cohort - NS-PARK
The aim of NS-PARK cohort are to describe the natural history of Parkinson's disease (PD), and to propose patients stratification models based on PD pathophysiological mechanisms.
- Trial name
- NS-PARK (NCT04888364)
- Where
- France
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Pre-clinical Studies With or Without Spin By French-speaking Population
The main objective of this study is to compare the interpretation of health news items reporting results of pre-clinical studies with or without spin (i.e., distortion of research results).
- Trial name
- NCT03071627
- Testing
- New items with spin, New items without spin
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychiatric Disorder, Substance Use Disorders
Prevalence of Psychiatric and Substance Abuse Disorders Among People in Precarious Situations in Cayenne
This is an observational, descriptive, cross-sectional, single-center study. The main objective of the study is to estimate the prevalence of the main psychiatric disorders and substance abuse disorders among people living in…
- Trial name
- EPICEA (NCT06065553)
- Where
- French Guiana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Intestinal Bacteria Flora Disturbance
Multi-Antibiotic Resistance Carriage in Gut Flora
Prevalence Study evaluating the acquisition of carriage of multidrug-resistant Gram-negative bacteria (MDRGNB) in the gut flora in volunteers of French Armed Forces staying from 4 to 6 months outside France.
- Trial name
- MARC (NCT01591538)
- Where
- France
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Da Volterra
Food Insecurity, Pregnancy Related
Food and Nutrition Insecurity During Pregnancy in French Guiana
This is a cross-sectional study of a representative sample of women who gave birth in the 3 maternity hospitals of French Guiana.
- Trial name
- NutriPouTiMoun (NCT05653128)
- Where
- 3 sites in French Guiana
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
French PNNS Guidelines in Vascular Function
Impact of Dietary Status on Vascular Function Before and After a Standardized Breakfast. An "Exposed/Unexposed" Study Embedded in the SUVIMAX2 Cohort
In France, primary cardiovascular and metabolic prevention is supported by the French National Program for Nutrition and Health (PNNS: Programme National Nutrition Santé).
- Trial name
- Nutri-MicroVas (NCT01579409)
- Testing
- PNNS guidelines
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Anxiety Disorders, Depressive Disorder
Anxiety and / or Depressive Disorders in a Population of French Airline Pilot
Throughout their career, the medical abilities of airline pilots are regularly assessed. This population is exposed to occupational constraints and risks, in particular psychosocial, and could constitute a population at risk of…
- Trial name
- AEROPSY (NCT05446519)
- Testing
- Survey
- Where
- France
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Well-being
Study of Children's Well-being After the COVID-19 Pandemic in Belgian French-speaking Primary Schools
In order to limit the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a significant numbers of measures were taken worldwide.
- Trial name
- DYNAtracs (NCT05747638)
- Testing
- Revised Children's Manifest Anxiety Scale (RCMAS)
- Where
- Belgium
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Cardiovascular Disease
Feasibility and Usability of a Pedometer in a Cardiovascular Disease Prevention Program for French-speaking Canadians
The purpose of this prospective randomized controlled trial (RCT) is to evaluate the feasibility and usability of a commercial pedometer and web application in a case-managed home-based Cardiovascular disease prevention and…
- Trial name
- PiezoRx (NCT02837471)
- Testing
- PiezoRx medical grade pedometer
- Where
- 2 sites in Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP)
French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls
The goal of this study is to learn whether people living with severe psychiatric disorders can be grouped into more homogeneous subgroups, across usual diagnostic categories, based on two key dimensions: social withdrawal and…
- Conditions
- Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive Disorder (MDD
- Trial name
- FRENCH-MINDS (NCT07881016)
- Testing
- 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments
- Where
- 17 sites in France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Rheumatoid Arthritis
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA), affects between 0.3% and 1.0% of the population, it can lead to progressive joint destruction and severe disability.
- Trial name
- HLAPRPA (NCT01111357)
- Testing
- Collect of 10 ml of peripheric blood for DNA extraction
- Where
- Martinique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Phase I/II (Non-randomized) Trials With or Without Spin by French-speaking Population
The main objective of this study is to compare the interpretation of health news items reporting results of phase I/II (non-randomized) trials with or without spin (i.e., distortion of research results).
- Trial name
- NCT03094130
- Testing
- News items with spin, News items without spin
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19
Prevalence of COVID-19 in a French Dependent Care Facility for the Elderly and in a French Long-term Care Unit: Observational Study
The aim of this study is to evaluate the prevalence of COVID-19 among the residents and geriatric inpatients of the care facilities attached to the Centre Hospitalier Sud Essonne (a general hospital located in Ile-de-France…
- Trial name
- SPEED-COVID (NCT04872699)
- Testing
- Serology testing, RT PCR
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Sud Essonne
Risk Management, Primary Health Care
Assessment of a Multifaceted Risk Management Program in French Multiprofessional Offices in Primary Care
Avoidable care associated incidents are relatively frequent in primary care. In France for example, avoidable incidents rate is estimated to 22/1000 medical acts from general practitioners.
- Conditions
- Risk Management, Primary Health Care, Patient Safety
- Trial name
- PRisM (NCT02403388)
- Testing
- PRisM
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Food Intake Regulation in Healthy Children
Eating in the Absence of Hunger and Caloric Compensation in Preschool Children, Link With Parental Feeding Practices
Objectives: The aims were to measure caloric compensation (CC) and eating in the absence of hunger (EAH) in 2 to 7 year-old French children in their regular eating context and to link these measurements with individual…
- Trial name
- HabEatWP31 (NCT01843712)
- Where
- France
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Idiopathic Bronchiectasis
Genetic Study of the Dilatations of the Idiopathic Bronchi in French Polynesia
Bronchiectasis, defined by an increase in bronchial caliber and thickening of the bronchial wall, is associated with recurrent respiratory infections, chronic cough and bronchorrhea, and a frequent progression to chronic…
- Trial name
- NCT04417777
- Testing
- Blood Test
- Where
- French Polynesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Chronic Ankle Instability
On the ICC's Path: a Prevalence Study
The number of trailers is growing all the time, and TRu seems to be a risky activity for the ankle joint. Ankle sprains can lead to significant health consequences, as in the case of chronic ankle instability.
- Trial name
- SSICC (NCT06269471)
- Where
- France
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cancer
Cost of Cancer Diagnosis Using Next-generation Sequencing Targeted Gene Panels in Routine Practice
The aim of this study was to measure the total cost of performing next-generation sequencing (NGS) in clinical practice in France, in both germline and somatic cancer genetics.
- Trial name
- NCT04656717
- Testing
- Measure of the total cost of performing next-generation sequencing (NGS)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Polycystic Kidney Diseases
Outcome of Autosomal Dominant Polycystic Kidney Disease Patients on Peritoneal Dialysis: a National Retrospective Study Based on Two French Registries (the French Language Peritoneal Dialysis Registry and the French Renal Epidemiology and Information Network).
Pathological features of Autosomal Dominant Polycystic Kidney disease (ADPKD) include enlarged kidney volume, a higher frequency of digestive diverticulitis and abdominal wall hernias.
- Trial name
- ADPKDPD (NCT03948113)
- Testing
- Dialysis
- Where
- France
- Volunteers
- 17,350 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Cancer
Mechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and Salaried Staff From a French Anti-cancer Center
Special populations are people with a risk to dévelop severe forms of a disease. The immunogenicity and efficacy of vaccines in this population may be different compared of the general population.
- Trial name
- CANSEROVAX (NCT04935528)
- Testing
- serology and ELISPOT test, serology
- Where
- France
- Volunteers
- 539 people, healthy volunteers welcome
- Sponsor
- Centre Georges Francois Leclerc