Clinical trials: FRENCH STUDY
Memory Disorders, Alzheimer Disease
Memory Problems Perceptions Among Patients and Accompaniers During Diagnosis Process :
This study aims to prospectively examine the memory problem perceptions of patients with memory complaints [MCs] and their accompaniers during the diagnostic process.
- Trial name
- REMAD (NCT02299154)
- Testing
- Psychological questionnaires
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Rhinitis
Efficacy and Safety Study of Nasacort in Chronic Non Allergic and Non Infectious Rhinitis in Adults
To demonstrate the superiority of the clinical efficacy of 12 weeks' treatment with Nasacort versus placebo in adult patients presenting with Chronic Non Allergic and Non Infectious Rhinitis
- Trial name
- RhiCNANI (NCT00344942)
- Testing
- triamcinolone acetonide
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Sanofi
Intensive Care, Supportive Care
A Prospective Study Evaluating the Feasibility and Ethical Perspective of Maastricht III Organ Procurement in French Intensive Care Unit Patients
The Maastricht III procedure consists of performing organ donation in patients in whom cardiac arrest is consecutive to a decision to withdraw life support.This MIII procedure is not applied in France, in contrast with other…
- Conditions
- Intensive Care, Supportive Care, Withdrawal of Life Support
- Trial name
- MIII (NCT01662375)
- Testing
- Surveillance and interview
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Nantes University Hospital
Radiotherapy
Prospective Registration of mOrbidity and Mortality, individUal radioSensitivity and Radiation Technique (PROUST)
Background: Recently, an increasing international interest has arisen in using morbidity and mortality rates to monitor the quality of hospital cares (1, 2).
- Trial name
- PROUST (NCT04253288)
- Testing
- Morbidity Mortality Review (MMR)
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronavirus Infections, COVID19 Outbreak in France
Study of the Increase in ICU Beds Capacity During COVID-19 Pandemic in France
For preventing the overwhelming of ICU beds capacity during COVID-19 pandemic in France, national and regional Health-Care institutions decided to optimize the Intensive Care Unit beds availability by opening new ICU beds in…
- Trial name
- FRENCH ICU (NCT04420286)
- Where
- France
- Volunteers
- 9,860 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Non Traumatic Acute Brain Injury
Non Traumatic Neuro-Vascular Diseases Critical Complications : a Prospective Cohort Study
The purpose of this observational epidemiological study is to investigate the management and the complications associated with Non Traumatic Neuro-Vascular Diseases.
- Trial name
- ATLANREA (NCT02714387)
- Testing
- Collection of medical data
- Where
- 6 sites in France
- Volunteers
- 5,000 people
- Sponsor
- Nantes University Hospital
Non Valvular Atrial Fibrillation (nv AF)
Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 75 Years and Over Suffering From Non Valvular Atrial Fibrillation (nv AF)
"The aim of the study is to compare, in real life, the risk benefit (including both major bleeding and thrombotic events (TE) and death from any cause) associated with direct oral anticoagulants (DOAC) and with anti vitamin K…
- Trial name
- Presage-Aco (NCT02906527)
- Testing
- Non-exposed group, Exposed group
- Volunteers
- 150,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Pre-clinical Studies With or Without Spin By French-speaking Population
The main objective of this study is to compare the interpretation of health news items reporting results of pre-clinical studies with or without spin (i.e., distortion of research results).
- Trial name
- NCT03071627
- Testing
- New items with spin, New items without spin
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychiatric Disorder, Substance Use Disorders
Prevalence of Psychiatric and Substance Abuse Disorders Among People in Precarious Situations in Cayenne
This is an observational, descriptive, cross-sectional, single-center study. The main objective of the study is to estimate the prevalence of the main psychiatric disorders and substance abuse disorders among people living in…
- Trial name
- EPICEA (NCT06065553)
- Where
- French Guiana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Elective Fertility Preservation
FRench Elective Oocyte prEservation: a Multicenter Study thrEe Years Later
Previously reserved for pathological cases, oocyte cryopreservation for non-medical reason also named elective fertility preservation (EFP) is now authorized in France for women aged 29 to 37 following the revision of the…
- Trial name
- FREEZE-FR (NCT07138469)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 351 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hepatocellular Carcinoma
Influence of Social Determinants of Health on the Management of HCC in the French National Cohort Study CHIEF
With 8,000 related deaths per year, HCC is one of the most dangerous cancers in France. The main reason for the poor prognosis of HCC is most often a diagnosis at an advanced stage ineligible for curative treatment.
- Trial name
- SOCIAL-CHIEF (NCT05128123)
- Where
- France
- Volunteers
- 1,600 people
- Sponsor
- University Hospital, Grenoble
Aortic Infections and Inflammations, Mycotic Aneurysm
Study of the Aortic and Large Arterial Vessel Infections
Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions.
- Conditions
- Aortic Infections and Inflammations, Mycotic Aneurysm, Arterial Infections and Inflammations, Prosthetic Infection
- Trial name
- Repia (NCT05660733)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Inflammatory Bowel Diseases
Population Based Evaluation of the Use of TNFα Antagonists in Pregnant Women With Inflammatory Bowel Diseases
: Inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC) need long term treatments which can conflict with a desire of pregnancy in women.
- Trial name
- EVASION (NCT03134508)
- Testing
- treated by antiTNFα, not treated by antiTNFα
- Where
- France
- Volunteers
- 8,726 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intestinal Bacteria Flora Disturbance
Multi-Antibiotic Resistance Carriage in Gut Flora
Prevalence Study evaluating the acquisition of carriage of multidrug-resistant Gram-negative bacteria (MDRGNB) in the gut flora in volunteers of French Armed Forces staying from 4 to 6 months outside France.
- Trial name
- MARC (NCT01591538)
- Where
- France
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Da Volterra
Diabetic Retinopathy, Artificial Intelligence
Screening for Diabetic Retinopathy in Pharmacies With Artificial Intelligence Enhanced Retinophotography
Diabetic retinopathy is frequent, potentially severe with visual threat, health costly and represents a major public health problem.
- Conditions
- Diabetic Retinopathy, Artificial Intelligence, Diabetes Mellitus
- Trial name
- DIABeyeIA (NCT05452993)
- Testing
- Analysed Retinophotography
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Caen
Myelodysplastic Syndrome
Spanish Registry of Erythropoietic Stimulating Agents Study
Reviewing Spanish record of myelodysplastic syndromes (RESMD) data base in the group of patients with MDS. The information will be collected retrospectively from diagnosis of MDS, until the date of December 31, 2011.
- Trial name
- SPRESAS (NCT01739452)
- Volunteers
- 722 people
- Sponsor
- Grupo Español de Síndromes Mielodisplásicos
Neoplasms, Oncology
An Observational Study of the Prevalence of Patients Requiring Palliative Care in French Anti-cancer Centers.
The purpose of this observational study is to determine the proportion of patients with a score greater than 3/10 to the questionnaire PALLIA-10.
- Trial name
- PREPA-10 (NCT02479061)
- Where
- 15 sites in France
- Volunteers
- 846 people
- Sponsor
- Centre Leon Berard
Cancer, COVID
The GCO-002 CACOVID-19 Cohort: a French Nationwide Multicenter Study of COVID-19 Infected Cancer Patients
Since December 2019, China and then the rest of the world have been affected by the rapid development of a new coronavirus, SARS-CoV-2 (severe acute respiratory syndrome corona virus 2).
- Conditions
- Cancer, COVID, Solid Tumor, Social Inequality
- Trial name
- CACOVID-19 (NCT04397575)
- Where
- 148 sites in France
- Volunteers
- 1,523 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Atopic Dermatitis
French Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (AD)
The objective of the study is to describe the therapeutic management of patients more than or equal to 18 years old eligible for systemic therapy or treated by systemic therapy for atopic dermatitis (AD).
- Trial name
- FRAME (NCT06837454)
- Where
- 61 sites in France
- Volunteers
- 600 people
- Sponsor
- Sanofi
Renal Transplantation
A Study of Renal Transplant Patients Converted From the Twice Per Day Form of Tacrolimus (Prograf®) to the Once Per Day Form (Advagraf®)
Assessment in a real situation of the conversion conditions, the efficacy and the safety of the treatment with tacrolimus in renal transplant patients converted from the tacrolimus twice per day form (Prograf®) to the tacrolimus…
- Trial name
- OPALE (NCT02147938)
- Testing
- Tacrolimus
- Where
- 26 sites in France
- Volunteers
- 578 people
- Sponsor
- Astellas Pharma S.A.S.