Clinical trials: Facet Joint Pain
Facet Joint Pain
PNS vs RFA for Facet Joint Pain
Radiofrequency ablation of the medial nerve is the current surgical treatment for back pain originating from the facet joints in the spine. However, this procedure causes denervation of spinal muscles.
- Trial name
- NCT05952518
- Testing
- Sprint PNS system, Radiofrequency Ablation
- Where
- United States
- Sponsor
- Penn State University
Degenerative Arthropathy of Lumbar Spinal Facet Joint
Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study
Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.
- Trial name
- NCT03304730
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital Israelita Albert Einstein
Chronic Low Back Pain, Lumbar Facet Joint Degeneration
Association of Subcutaneous Fat Index, Paraspinal Muscle Characteristics, and Facet Morphology With Lumbar Facet Joint Degeneration
This prospective observational study aims to investigate the association between subcutaneous fat index, paraspinal muscle characteristics, facet morphology, and lumbar facet joint degeneration in adults with chronic low back…
- Trial name
- NCT07860697
- Testing
- Lumbar Magnetic Resonance Imaging (MRI)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Cervical Pain, Cervical Facet Joint Pain
Trident Multi-tined Cannula for Cervical MBRFA Compared to the Conventional Cannula
Cervical medial branch radiofrequency ablation (CMBRFA) is an effective treatment for cervical facet pain. The efficacy of CMBRFA was proven by studies published in the late 1990's and early 2000's.
- Trial name
- NCT05424198
- Testing
- Cervical Medial Branch Radiofrequency Ablation
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Facet Joint Pain, Arthropathy
Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis
The purpose of this study is to compare the incidence of post-neurotomy neuritis (PNN) in adult patients undergoing radiofrequency neurotomy (RFN) for spine facet and sacroiliac joint pain, comparing those who receive a local…
- Conditions
- Facet Joint Pain, Arthropathy, Sacroiliac Joint Dysfunction, Post-neurotomy Neuritis
- Trial name
- PNN (NCT07839195)
- Testing
- Dexamethasone, Normal Saline, Bupivacaine
- Where
- Thailand
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Cervical Facet Joint Pain, Chronic Pain
Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or…
- Conditions
- Cervical Facet Joint Pain, Chronic Pain, Neck Pain
- Trial name
- NCT05450679
- Testing
- Cervical Radiofrequency Ablation (RFA)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Johns Hopkins University
Facet Joint Arthropathy, Pain
Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy
This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to facet arthropathy…
- Conditions
- Facet Joint Arthropathy, Pain, Osteoarthritis
- Trial name
- NCT06965452
- Testing
- Spinal angiography and embolization/ Embozene Microspheres
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Lower Back Pain of Disc Origin, Joint Facet Syndrome
Long-Term Evaluation of the Performance and Safety of the IntraSPINE® Interlaminar Implant in the Treatment of Lumbar Degenerative Disc Disease
This is an observational study designed as an extension of a prospective study conducted between 2012 and 2017. Patients who were originally enrolled in the initial study are being recontacted for follow-up assessment, including…
- Conditions
- Lower Back Pain of Disc Origin, Joint Facet Syndrome, Lumbar Canal Stenosis, Spinal Disease
- Trial name
- IntraLT (NCT07790328)
- Testing
- IntraSPINE
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Cousin Biotech
Pain, Chronic, Facet Joint Pain
Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks
This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).
- Conditions
- Pain, Chronic, Facet Joint Pain, Pain, Procedural, Analgesia
- Trial name
- OMEGA (NCT05961800)
- Testing
- Cutaneous Probe, Quantitative Sensory Testing, Computer Tasks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Facet-Mediated Low Back Pain, Lumbar Facet Joint Osteoarthritis
Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy
The purpose of this research study is to evaluate the safety and effect of bone marrow-derived stem cells for the treatment of low back pain.
- Trial name
- CELLKINE II (NCT06001853)
- Testing
- BM-MSC injection, DSMO Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Facet Joint Arthropathy, Lower Back Pain
Association Between Trendelenburg Sign and Lumbar MRI Abnormalities
The Trendelenburg sign is a common clinical finding indicating hip abductor dysfunction and altered pelvic stability. The relationship between the Trendelenburg sign, spinopelvic biomechanics, hip muscle strength, and lumbar…
- Trial name
- NCT07629466
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bahçeşehir University
Cervical Facetogenic Pain, Chronic Neck Pain
Cervical Medial Branch Block Versus Ipsilateral Cervical Erector Spinae Plane Block
This prospective randomized controlled study aims to compare the analgesic effectiveness of ultrasound-guided cervical medial branch block and ipsilateral cervical erector spinae plane block in patients with cervical facetogenic…
- Conditions
- Cervical Facetogenic Pain, Chronic Neck Pain, Cervical Facet Joint Syndrome
- Trial name
- CERVESP (NCT07595406)
- Testing
- Ultrasound-guided cervical medial branch block, Ultrasound-guided cervical erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Low Back Pain, Lumbar Facet Joint Osteoarthritis
Ultrasound-Guided Lumbar Facet Joint Injections for Facet-Related Pain: A Randomized Comparison of Saline, Steroid, and 5% Dextrose
This study aims to evaluate the effectiveness of prolotherapy using 5% dextrose compared to steroid and saline injections in patients with lumbar facet joint-related low back pain.
- Trial name
- NCT07528794
- Testing
- Dextrose Injection, Steroid Injection, Saline Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Facet Joint Pain
ITX24-01 in Adult Male and Female Patients With Select Types of Severe Chronic Neck- and Lower Back Pain
The study is a single ascending dose (SAD), single-center, randomised, double-blind, placebo-controlled Phase 1b clinical trial designed to evaluate the safety, tolerability, and preliminary analgesic efficacy of ITX24-01 in…
- Trial name
- NCT07520240
- Testing
- ITX24-01, Normal Saline (0.9% NaCl)
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Interventional AnalgesiX Inc.
Facet Joint Pain; Low Back Pain
Sidekick vs Conventional Cannula in Lumbar Medial Branch Radiofrequency Ablation
Lumbar facet joint-mediated chronic low back pain is a common cause of disability. Radiofrequency ablation (RFA) of the lumbar medial branches is an established interventional pain treatment.
- Trial name
- SIDE-RFA (NCT07475689)
- Testing
- Lumbar Medial Branch Radiofrequency Ablation, Triamcinolone (20 g), bupivacain 0.5% 2ml
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Facet Joints; Degeneration, Back Pain
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects.
- Conditions
- Facet Joints; Degeneration, Back Pain, Facet Joint Pain
- Trial name
- NCT05909709
- Testing
- Alocyte low dose, Alocyte medium dose, Alocyte high dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alimorad Farshchian
Non-specific Low Back Pain (NSLBP), Facet Joint Syndrome
Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation Of Nonspecific Chronic Pain
Chronic musculoskeletal pain of non-specific origin affects approximately 30% of the global population. Beyond its prevalence, it represents a serious health and socioeconomic problem.
- Trial name
- PENSAR (NCT07273006)
- Testing
- Nerve block with Lidocain, Percutaneous electrical nerve stimulation
- Where
- Poland
- Volunteers
- 82 people
- Sponsor
- Universidad Complutense de Madrid
Lumber Facet Joint Pain(Lower Back Pain ) Relief by Cooled Radiofrequency or Thermal Radiofrequency Denervation
Impact OF Cooled Versus Thermal Radiofrequency Denervation In Management Of Chronic Lumber Facet Joint Pain
Chronic lumber facet joint pain is defined according to international association of study of pain (IASP)as multifactorial phenomenon of pain that persist more than 3 months after an injury and /or beyond the usual course of an…
- Trial name
- NCT07309731
- Testing
- thermal radio frequency denervation, Cooled Radiofrequency denervation
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Lower Back Pain Chronic, Lumbar Disc Disease
PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study
This study aimed to evaluate the efficacy and safety of a comprehensive, multi-target injection protocol, termed 'PRP Spinoplasty,' for managing chronic LBP stemming from concurrent lumbar disc and facet joint disease with…
- Conditions
- Lower Back Pain Chronic, Lumbar Disc Disease, Facet Joint Arthritis
- Trial name
- NCT07268885
- Testing
- Spinoplasty with Platelet Rich Plasma
- Where
- Palestinian Territories
- Volunteers
- 35 people
- Sponsor
- Allmed Medical Center