Clinical trials: Facet Joint Pain
Lower Back Pain Chronic
The Relation of the Anatomic Morphology of Lumbar Transverse Processes and the Success Rate of Facet Joint Radiofrequency Denervation
Adult patients who were planned for lumbar facet joint medial branch nerve Radiofrequency ablation under fluoroscopic guidance because of facet joint-originated chronic lower back pain will be included in this study.
- Trial name
- NCT07076810
- Testing
- Lumbar facet joints medial branch nerve radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ondokuz Mayıs University
Low Back Pain, Facet Joint Pain
The Effect of Stabilization Exercises After Radiofrequency Lumbar Facet Denervation
A gap of knowledge exists on the understanding of the acute effects of stabilization exercises on pain, disability and physical performance when applied after radiofrequency denervation.
- Conditions
- Low Back Pain, Facet Joint Pain, Radiofrequency Denervation, Pain
- Trial name
- NCT03444493
- Testing
- Exercise
- Volunteers
- 39 people
- Sponsor
- Hacettepe University
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Lower Back Pain of Disc Origin, Joint Facet Syndrome
Long-Term Evaluation of the Performance and Safety of the IntraSPINE® Interlaminar Implant in the Treatment of Lumbar Degenerative Disc Disease
This is an observational study designed as an extension of a prospective study conducted between 2012 and 2017. Patients who were originally enrolled in the initial study are being recontacted for follow-up assessment, including…
- Conditions
- Lower Back Pain of Disc Origin, Joint Facet Syndrome, Lumbar Canal Stenosis, Spinal Disease
- Trial name
- IntraLT (NCT07790328)
- Testing
- IntraSPINE
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Cousin Biotech
Low Back Pain, Facet Joint Pain
Association Between Clinical Signs and MRI Findings of the Lumbar Facet Joints
The purpose of this study is to determine 1. the prevalence of lumbar facet joint pain detected by manual segmental provocation tests 2. the prevalence of MRI findings of the lumbar facet joints (hypertrophy, effusion, edema) 3.
- Trial name
- NCT01628939
- Testing
- MRI of the lumbar spine, manual segmental examination of the lumbar facet joints
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Christoph Maier, Prof. Dr.
Facet Joints; Degeneration, Back Pain
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects.
- Conditions
- Facet Joints; Degeneration, Back Pain, Facet Joint Pain
- Trial name
- NCT05909709
- Testing
- Alocyte low dose, Alocyte medium dose, Alocyte high dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alimorad Farshchian
Low Back Pain, Zygapophyseal Joint Arthritis
Endogenous Opioid Response to Injections
This study will study pain relief after spine injections that are used to guide care. Some improvements in pain from a procedure might be from placebo effect rather than the physiological effect of the procedure.
- Trial name
- AEOUI2 (NCT06666621)
- Testing
- Normal saline infusion, Naloxone infusion
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Middle Tennessee Research Institute
Lower Back Pain
Using MRI Scans to Evaluate Spinal Manipulation
Lumbar spinal manipulation, or chiropractic adjusting, is thought to separate the surfaces of the spinal joints and thereby relieve lower back pain.
- Trial name
- NCT00070902
- Testing
- Lumbar side-posture spinal adjusting
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Low Back Pain, Facet Joint Pain
EuroPainClinics® Study IV (Prospective Observational Study)
In this prospective observational trial the effect of the Endoscopic rhizotomy microinvasive therapy should be examined in (approximately 150) adult patients with low back pain positive for facet joint pain component.
- Trial name
- EPCSIV (NCT03039296)
- Testing
- Endoscopic rhizotomy
- Where
- Slovakia
- Volunteers
- 4 people
- Sponsor
- EPC Education s.r.o.
Whiplash Injury, Whiplash Injury of Cervical Spine
Radiofrequency Versus Cervical Fusion for Chronic Whiplash
Chronic neck pain after whiplash injury is a common and disabling condition that can significantly affect quality of life, daily activities, and psychological well-being.
- Conditions
- Whiplash Injury, Whiplash Injury of Cervical Spine, Chronic Neck Pain, Post-Traumatic Neck Pain
- Trial name
- WHIPLASH-RFvsA (NCT07535515)
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Valencia
Facet Joint Pain
TTAX03 for the Treatment of Lumbosacral Facet Joint Pain
This is a pilot study examining the safety and efficacy of a single intra-articular (IA) injection of TTAX03 per joint to relieve severe spinal facet joint (FJ) pain and improve function in subjects with facet joint pain (FJP) in…
- Trial name
- NCT06236308
- Testing
- TTAX03 10mg, TTAX03 25mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- BioTissue Holdings, Inc
Low Back Pain, Facet Joint Pain
Cryoneurolysis for Facet Mediated Chronic Low Back Pain
This is a single-center, randomized, pilot study in adult subjects with facet mediated CLBP. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº medial branch cryoneurolysis or…
- Trial name
- NCT06016127
- Testing
- iovera system, Radiofrequency ablation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Facet Joint Syndrome
Multifidus Muscle Twitch on the Prognosis of Lumbar Medial Branch RF
The investigators collected data and chart from the patients who were diagnosed facet joint syndrome and underwent lumbar RF medial branch neurotomy between January 2009 and June 2014.
- Trial name
- NCT02580383
- Testing
- Radiofrequency neurotomy of lumbar medial branch
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Severance Hospital
Neck Pain, Low Back Pain
The Effect of Radiofrequency-treatment on Patients With Facet-joint Pain in Cervical- and Lumbar-columna
There is conflicting evidence on whether radio-frequency neurotomy of the medial branch has a significant effect on pain in patients with chronic unilateral facet joint neck and back pain.
- Trial name
- NCT00476684
- Testing
- radiofrequency treatment
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- Norwegian University of Science and Technology
Neck Pain, Zygapophyseal Joint Arthritis
End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves
Aim of the EndPaRL study is to compare the efficacy and effectiveness of the two techniques utilizing sharp straight conventional radiofrequency needle with a trident needle for radiofrequency neurotomy of Cervical Medial Branch…
- Trial name
- EndPaRL (NCT05818774)
- Testing
- Radiofrequency neurotomy (RFN) of Cervical Medial Branch Nerves (CMBNn) with parallel lesioning, Radiofrequency neurotomy (RFN) of Cervical Medial Branch Nerves (CMBNn) with end-on lesioning with multitined trident cannulae
- Where
- 3 sites in Canada, Spain
- Volunteers
- 72 people
- Sponsor
- University Health Network, Toronto
Lumbar Facet Syndrome
A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Chronic, non-neurogenic low back pain (CLBP) is a common condition that affects many individuals across their lives. The lumbar facet joint has been implicated as an important source of CLBP, with a prevalence of 15-45%.
- Trial name
- NCT03614793
- Testing
- Cooled Radiofrequency Ablation of Medial Branch Nerves versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Utah
Vertebral Compression Fracture, Facet Joint Pain
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
The purpose of this study is to test the efficacy of radiofrequency ablation of the medial branch nerves (RFA-MBN) in relieving pain and improving physical function in patients with subacute and chronic vertebral compression…
- Trial name
- NCT03651804
- Testing
- Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Facet Joint Pain
ITX24-01 in Adult Male and Female Patients With Select Types of Severe Chronic Neck- and Lower Back Pain
The study is a single ascending dose (SAD), single-center, randomised, double-blind, placebo-controlled Phase 1b clinical trial designed to evaluate the safety, tolerability, and preliminary analgesic efficacy of ITX24-01 in…
- Trial name
- NCT07520240
- Testing
- ITX24-01, Normal Saline (0.9% NaCl)
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Interventional AnalgesiX Inc.
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University