Clinical trials: Facet Joint Syndrome
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Cervical Facetogenic Pain, Chronic Neck Pain
Cervical Medial Branch Block Versus Ipsilateral Cervical Erector Spinae Plane Block
This prospective randomized controlled study aims to compare the analgesic effectiveness of ultrasound-guided cervical medial branch block and ipsilateral cervical erector spinae plane block in patients with cervical facetogenic…
- Conditions
- Cervical Facetogenic Pain, Chronic Neck Pain, Cervical Facet Joint Syndrome
- Trial name
- CERVESP (NCT07595406)
- Testing
- Ultrasound-guided cervical medial branch block, Ultrasound-guided cervical erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara City Hospital Bilkent
Vertebral Compression Fracture, Facet Joint Pain
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
The purpose of this study is to test the efficacy of radiofrequency ablation of the medial branch nerves (RFA-MBN) in relieving pain and improving physical function in patients with subacute and chronic vertebral compression…
- Trial name
- NCT03651804
- Testing
- Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Neck Pain, Radiofrequency Ablation
Comparison of a Multi-tined Cannula Versus a Conventional Cannula for Cervical Medial Branch Radiofrequency Ablation in Chronic Neck Pain
Chronic neck pain is a common disorder for spine specialists. Radiofrequency ablation of medial branches has been proven effective in selected patients for relieving pain.
- Conditions
- Neck Pain, Radiofrequency Ablation, Facet Joint Pain
- Trial name
- NCT04152954
- Testing
- Radiofrequency ablation of cervical medial branches
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Whiplash Injury, Whiplash Injury of Cervical Spine
Radiofrequency Versus Cervical Fusion for Chronic Whiplash
Chronic neck pain after whiplash injury is a common and disabling condition that can significantly affect quality of life, daily activities, and psychological well-being.
- Conditions
- Whiplash Injury, Whiplash Injury of Cervical Spine, Chronic Neck Pain, Post-Traumatic Neck Pain
- Trial name
- WHIPLASH-RFvsA (NCT07535515)
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Valencia
Degenerative Disc Disease, Facet Joint Syndrome
Intradiscal and Intra-articular Injection of Autologous Platelet-Rich-Plasma (PRP) in Patients With Lumbar Degenerative Disc Disease and Facet Joint Syndrome
Autologous Platelet-Rich-Plasma (PRP) represents a regenerative therapy that has gained remarkable ground in the field of orthopaedics in recent years.
- Trial name
- NCT04816747
- Testing
- Autologous PRP
- Volunteers
- 50 people
- Sponsor
- Stylianos Kapetanakis
Cervical Facet Joint Pain, Chronic Pain
Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or…
- Conditions
- Cervical Facet Joint Pain, Chronic Pain, Neck Pain
- Trial name
- NCT05450679
- Testing
- Cervical Radiofrequency Ablation (RFA)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Johns Hopkins University
Facet Joints; Degeneration, Back Pain
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects.
- Conditions
- Facet Joints; Degeneration, Back Pain, Facet Joint Pain
- Trial name
- NCT05909709
- Testing
- Alocyte low dose, Alocyte medium dose, Alocyte high dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alimorad Farshchian
Lumbar Facet Joint Pain
One-Needle Vs Three-Needle Radiofrequency in Low Back Pain Due to Facet Joint Arthritis
Failure of RFA has been attributed to technical failure of coagulating the nerve or coagulation of a minimal section of the nerve, allowing for early reinnervation.
- Trial name
- NCT05137652
- Testing
- Radiofrequency ablation of medial nerve using single needle approach, Radiofrequency ablation of medial nerve using three needle approach
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Facet Joint Pain
The Lumbar Trident Study
This observational retrospective study evaluates the efficacy of RF with the three-tined expandable electrode needle compared to before treatment in the treatment of chronic lumbar facet joint pain.
- Trial name
- NCT05949970
- Testing
- Radiofrequency denervation of the lumbar facet joint
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Ospedale Regionale di Lugano
Facet Joint Pain
Multimodal PT With and Without Proprioceptive Training in Lumber FJS
This will be a randomized clinical trial. The study will be conducted at Pakistan Railways General Hospital Rawalpindi and Riphah International Hospital Islamabad. Patients with FJS will be included.
- Trial name
- NCT05931653
- Testing
- Multimodal Physical therapy, Proprioceptive training along with and Multimodal Physical therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Facet Joint Pain
Post Lumbar Radiofrequency Neurotomy Imaging
MRI imaging post radio frequency ablation procedure for facet arthritis
- Trial name
- NCT05122611
- Testing
- no intervention, imaging study only
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Non-specific Low Back Pain (NSLBP), Facet Joint Syndrome
Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation Of Nonspecific Chronic Pain
Chronic musculoskeletal pain of non-specific origin affects approximately 30% of the global population. Beyond its prevalence, it represents a serious health and socioeconomic problem.
- Trial name
- PENSAR (NCT07273006)
- Testing
- Nerve block with Lidocain, Percutaneous electrical nerve stimulation
- Where
- Poland
- Volunteers
- 82 people
- Sponsor
- Universidad Complutense de Madrid
Facet Syndrome of Lumbar Spine
RAMBAM 021: Safety and Initial Feasibility of the Neurolyser XR for the Treatment of Chronic Low Back Pain
Single arm pilot study to evaluate the safety and initial feasibility of the Neurolyser XR, a high intensity focused ultrasound device, for non-invasive treatment of axial chronic low back pain
- Trial name
- NCT04519541
- Testing
- Non-Invasive Thermal Ablation of the Medial Branch Nerves using the Neurolyser XR
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Neck Pain, Cervicalgia
Cortisone Shots for Neck Pain
The purpose of this study is to determine if cortisone shots in the neck are helpful in patients with certain MRI findings. Additionally, the investigators hope to learn if cervical facet joint steroid injections are beneficial…
- Conditions
- Neck Pain, Cervicalgia, Facet Joint Pain
- Trial name
- NCT03534531
- Testing
- Intra-articular cervical zygapophyseal joint injection
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Low Back Pain, Lumbar Facet Joint Pain
An Alternative Technique for Lumbar Medial Branch Radiofrequency: Comparison With the Empirical Technique
In spite that variable techniques for lumbar MBRF exists, the tunnel vision technique is widely recommended for exact radiofrequency needle placement.
- Conditions
- Low Back Pain, Lumbar Facet Joint Pain, Arthropathy
- Trial name
- MBRF LBP (NCT01300715)
- Testing
- lumbar medial branch radiofrequency neurotomy
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Low Back Pain, Facet Joint Pain
Cryoneurolysis for Facet Mediated Chronic Low Back Pain
This is a single-center, randomized, pilot study in adult subjects with facet mediated CLBP. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº medial branch cryoneurolysis or…
- Trial name
- NCT06016127
- Testing
- iovera system, Radiofrequency ablation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Facet Joint Pain
PNS vs RFA for Facet Joint Pain
Radiofrequency ablation of the medial nerve is the current surgical treatment for back pain originating from the facet joints in the spine. However, this procedure causes denervation of spinal muscles.
- Trial name
- NCT05952518
- Testing
- Sprint PNS system, Radiofrequency Ablation
- Where
- United States
- Sponsor
- Penn State University
Low Back Pain, Osteoarthritis
Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome
The prevalence of low back pain is estimated at 90% . Recent studies have shown that 15% to 52% of back pain is attributable to facet joint syndrome .
- Trial name
- IAPRP (NCT05105256)
- Testing
- Prednisolone, Platelet-rich plasma
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CHU de Reims