Clinical trials: Facet Joint Syndrome
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Lumbar Facet Syndrome
A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Chronic, non-neurogenic low back pain (CLBP) is a common condition that affects many individuals across their lives. The lumbar facet joint has been implicated as an important source of CLBP, with a prevalence of 15-45%.
- Trial name
- NCT03614793
- Testing
- Cooled Radiofrequency Ablation of Medial Branch Nerves versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Utah
Facet Joint Pain, Facet Syndrome of Lumbar Spine
Injections in the Diagnosis and Treatment of Lumbar Facet Syndrome
In suspected facet joints pain, it is recommended to perform nerve blocks to establish the diagnosis with positive results being and indicator of successful of most permanent treatment of facet pain by rhizolysis.
- Conditions
- Facet Joint Pain, Facet Syndrome of Lumbar Spine, Facet Joints; Degeneration
- Trial name
- NCT03871192
- Testing
- FACET JOINT UNDER CT GUIDANCE, NERVE BLOCK UNDER CT GUIDANCE, FACET JOINT UNDER FLUOROSCOPY GUIDANCE
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Low Back Pain
Conventional Radiofrequency, Pulse Radiofrequency, and TENS for Lumbar Facet Joint Pain
Objective: The objective of this study is to compare the efficacy of TENS (transcutaneous electrical nerve stimulation) therapy with those of the conventional radiofrequency and pulse radiofrequency therapies.
- Trial name
- NCT02942147
- Testing
- TENS, Conventional or Pulse Radiofrequency
- Volunteers
- 60 people
- Sponsor
- Ege University
Lumbar Facet Joint Pain, Low Back Pain
Medial Branch Blocks vs. Intra-articular Injections: Randomized, Controlled Study
Background: Facet interventions are the second most commonly performed procedure in pain clinics throughout the U.S, including in the military.
- Trial name
- NCT02002429
- Testing
- Intra-articular injection, Medial branch block, Saline injection
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Johns Hopkins University
Chronic Low Back Pain, Facet Joint Syndrome
MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain
This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA)…
- Trial name
- NCT03168802
- Testing
- MRgFUS ablation, Radiofrequency ablation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Hospital
Facet Syndrome of Lumbar Spine
Double Arm Pivotal Study to Evaluate the Neurolyser XR for the Treatment of Chronic Low Back Pain
Double arm pivotal study to evaluate the Neurolyser XR as a non-invasive treatment of axial chronic low back pain
- Trial name
- NCT05154448
- Testing
- Non-Invasive Thermal Ablation of the Medial Branch Nerves (Neurolyser XR)
- Where
- 10 sites in United States
- Volunteers
- 90 people
- Sponsor
- FUSMobile Inc.
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Low Back Pain, Facet Joint Pain
Ultrasound-Guided Thermocoagulation of Medial Nerve Branch in Lumbar Facet Joints Pain.
We propose here to evaluate the precision of lumbar thermocoagulation performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position.
- Conditions
- Low Back Pain, Facet Joint Pain, Facet Syndrome of Lumbar Spine, Chronic Low Back Pain
- Trial name
- NCT03564418
- Testing
- Ultrasound-Guided Thermocoagulation of Lumbar facet joints, Fluoroscopy-Guided Thermocoagulation of Lumbar facet joints
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Erasme University Hospital
Facet Joint Pain
A Multi-Site Study of the Zyga GlyDer Facet Restoration Device In Subjects With LUmbar FacET Pain Syndrome - DUET
A non-randomized, multi-site feasibility study to evaluate the safety of the Glyder Device in subjects with a history of lumbar facet joint disease (L2 to the sacrum) and successful neural ablation in which the facet joint is…
- Trial name
- DUET (NCT02179476)
- Testing
- Glyder
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Zyga Technology, Inc.
Back Pain
Ultrasound Guided Diagnostic Lumbar Medial Branch Blocks
Can an ultrasound machine be used to perform a diagnostic lumbar medial branch block?
- Trial name
- NCT00909272
- Testing
- Lumbar medial branch block, Ultrasound landmarks
- Where
- Canada
- Sponsor
- McMaster University
Joint Pain
Synvisc Injections for Lumbar Facet Joint Pain
The objective of this investigation is to evaluate the safety and efficacy of viscosupplementation in treating symptomatic lumbar facet joint arthropathy.
- Trial name
- NCT00325845
- Testing
- Synvisc viscosupplementation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Sheltering Arms Physical Rehabilitation Hospitals
Chronic Pain, Facet Joint Pain
Sensory Mapping of Lumbar Facet Joint Pain
Low back pain is a major contributor to the chronic pain burden in the community. Although there are numerous pain generators in the spine, lumbar facet joints are one of the most common sources of pain.
- Trial name
- SENS-MAP (NCT03323775)
- Testing
- Suprathreshold stimulation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Aberdeen
Lower Back Pain Chronic
The Relation of the Anatomic Morphology of Lumbar Transverse Processes and the Success Rate of Facet Joint Radiofrequency Denervation
Adult patients who were planned for lumbar facet joint medial branch nerve Radiofrequency ablation under fluoroscopic guidance because of facet joint-originated chronic lower back pain will be included in this study.
- Trial name
- NCT07076810
- Testing
- Lumbar facet joints medial branch nerve radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ondokuz Mayıs University
Facet Joint Arthropathy, Pain
Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy
This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to facet arthropathy…
- Conditions
- Facet Joint Arthropathy, Pain, Osteoarthritis
- Trial name
- NCT06965452
- Testing
- Spinal angiography and embolization/ Embozene Microspheres
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Facet Joint Pain
TTAX03 for the Treatment of Lumbosacral Facet Joint Pain
This is a pilot study examining the safety and efficacy of a single intra-articular (IA) injection of TTAX03 per joint to relieve severe spinal facet joint (FJ) pain and improve function in subjects with facet joint pain (FJP) in…
- Trial name
- NCT06236308
- Testing
- TTAX03 10mg, TTAX03 25mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- BioTissue Holdings, Inc
Low Back Pain
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
- Trial name
- NCT06361485
- Testing
- Lumbar Injections with 10cc's of Wharton's Jelly Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- R3 Stem Cell
Pain, Chronic, Facet Joint Pain
Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks
This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).
- Conditions
- Pain, Chronic, Facet Joint Pain, Pain, Procedural, Analgesia
- Trial name
- OMEGA (NCT05961800)
- Testing
- Cutaneous Probe, Quantitative Sensory Testing, Computer Tasks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Low Back Pain, Facet Joint Pain
The Effect of Stabilization Exercises After Radiofrequency Lumbar Facet Denervation
A gap of knowledge exists on the understanding of the acute effects of stabilization exercises on pain, disability and physical performance when applied after radiofrequency denervation.
- Conditions
- Low Back Pain, Facet Joint Pain, Radiofrequency Denervation, Pain
- Trial name
- NCT03444493
- Testing
- Exercise
- Volunteers
- 39 people
- Sponsor
- Hacettepe University
Lumbar Facet Joint Pain
Technical Description of Cooled Radiofrequency Ablation of Lumbar Medial Branches for the Treatment of Lumbar Facet Pain
This study aims to develop a technical description of lumbar medial branch ablation using the LumbarCool system. The procedure uses cooled radiofrequency (cooled-RF) technology in treating patients with diagnosed lumbar facet…
- Trial name
- NCT01590004
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mehul Desai