Clinical trials: Facial Dermatoses
Actinic Keratosis
Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up
The objective of the trial is to compare the short term efficacy of LEO 43204 gel with vehicle gel in AK on face or chest when applied topically once daily for 3 consecutive days as field treatment.
- Trial name
- NCT02547233
- Testing
- LEO 43204 gel, Vehicle gel
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- LEO Pharma
Lax Skin
Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators
Open-label, non-randomized single-arm prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT06333067
- Testing
- Sofwave
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Actinic Keratosis
Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest
The objective of the trial is to investigate efficacy and safety of ingenol mebutate gel for actinic keratosis applied to large treatment areas once daily for three consecutive days on face, scalp or chest.
- Trial name
- NCT02361216
- Testing
- Ingenol Mebutate, Vehicle
- Where
- United States
- Volunteers
- 729 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Acne Vulgaris
Comparison of Two Salicylic Acid Formulations
This study is a split face, paired-comparison, pilot study of at least 10 subjects to complete. Participants in this study will be patients seen at Children's Memorial Hospital, who are clinically diagnosed with mild to moderate…
- Trial name
- NCT00848744
- Testing
- Formulation A, Formulation B
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Seborrheic Keratosis
A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.
This is a randomized, double-blind, vehicle-controlled, parallel group study of A-101 Solution 40% compared with Vehicle Solution.
- Trial name
- NCT02667236
- Testing
- A-101 Solution, Vehicle Solution
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Aclaris Therapeutics, Inc.
Actinic Keratoses, Photodamage
Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage
To provide a treatment of both actinic keratoses and photodamage within one treatment.
- Trial name
- NCT07053852
- Testing
- Ameluz, Sciton HEROic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sherrif Ibrahim
Rosacea
Bioequivalence Study of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea on the Face
To compare the bioequivalence of Perrigo's azelaic acid foam product to Finacea Foam for the treatment of Inflammatory Lesions of Rosacea
- Trial name
- NCT02800148
- Testing
- Azelaic acid foam
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- Padagis LLC
Rosacea
Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea
A Randomized, Double-Blind, Multiple-Site, Placebo-Controlled, Parallel-Design Study to Evaluate the Safety and Therapeutic Equivalence of Brimonidine Topical Gel, 0.33% (Watson Laboratories, Inc., USA) to Reference Product…
- Trial name
- NCT02289352
- Testing
- Brimonidine
- Where
- 16 sites in United States
- Volunteers
- 462 people
- Sponsor
- Actavis Inc.
Hyperpigmentation, Photodamaged Skin
A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging
This open-label, multi-center clinical trial was conducted to evaluate the dual skincare regimen of vitamin C serum and moisturizing sunscreen SPF 45 to improve facial hyperpigmentation and photodamage after 12 weeks of twice…
- Conditions
- Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
- Trial name
- NCT05423873
- Testing
- Gentle Cleansing Lotion, Revision Skincare
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Laxity
Hybrid Fractional Laser for Treatment of Off Face Body Skin Quality
To demonstrate effectiveness of hybrid fractional laser for the treatment of poor skin quality on the decolletage, back of the hands and lower legs
- Trial name
- NCT03969485
- Testing
- Hybrid Fractional Laser
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Sciton
Psoriasis
A Study of Guselkumab in Naive or Bio-experienced Participants With Regional (Facial and Genital) Psoriasis
The purpose of this study is to investigate the effectiveness profile of guselkumab used in a real-life setting in participants with moderate facial and/or genital psoriasis.
- Trial name
- GULLIVER (NCT04439526)
- Testing
- Guselkumab
- Where
- 38 sites in Italy
- Volunteers
- 356 people
- Sponsor
- Janssen-Cilag S.p.A.
Eyelid Tumor, Xanthelasma Palpebrarum
Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors
This study aims to assess the long-term efficacy and safety of ultrapulse carbon dioxide (CO₂) laser excision in the treatment of eyelid tumors, including xanthelasma, pigmented nevi, keratoses, and so on.
- Conditions
- Eyelid Tumor, Xanthelasma Palpebrarum, Pigmented Nevi, Keratosis
- Trial name
- NCT06206681
- Testing
- Ultra-pulsed Carbon Dioxide Laser
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Actinic Keratoses
Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis
This Phase I study is designed to evaluate the systemic exposure and safety of KX2-391 Ointment in adult subjects when applied to an area of skin containing at least 5 clinically typical, visible, and discrete Actinic Keratosis…
- Trial name
- NCT03575780
- Testing
- KX2-391 Ointment 1%
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Athenex, Inc.
Actinic Keratosis
A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004)
This Phase III study was designed to evaluate the efficacy and safety of KX2-391 Ointment 1% in adult participants when applied to an area of skin containing 4-8 stable, clinically typical actinic keratosis (AK) lesions on the…
- Trial name
- NCT03285490
- Testing
- KX2-391 Ointment 1%
- Where
- 30 sites in United States
- Volunteers
- 351 people
- Sponsor
- Almirall, S.A.
Actinic Keratosis
Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2)
This clinical trial serves the purpose to compare the long-term effects of a treatment of actinic keratosis - your skin disorder - using Aldara® 5% cream (Imiquimod) or Solaraze® 3% gel (Diclofenac) on the face or the scalp.
- Trial name
- LEIDA 2 (NCT01453179)
- Testing
- Imiquimod, Diclofenac
- Where
- 17 sites in Austria, Germany
- Volunteers
- 221 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas
This study evaluates the safety and effectiveness of the UltraClear® 2,910 nm fractional ablative fiber laser for improving skin laxity and tissue lifting in the lower face, submental, and neck areas.
- Trial name
- UC 29-2026 (NCT07759817)
- Testing
- 2910 nm fiber laser (UltraClear®)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- FA Corporation