Clinical trials: Facial Injuries and Disorders
Zygomatic Fractures
Adequacy of One Point Fixation of Displaced Zygomatic Complex Fracture
Patients with unilateral non-comminuted zygomatic complex fracture undergo fixation of the complex by a customized plate at one point after 3D virtual simulation and reduction of the complex using Mimics software.
- Trial name
- NCT03484676
- Testing
- Titinium
- Volunteers
- 18 people
- Sponsor
- Cairo University
Inferior Alveolar Nerve Injuries
Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve.
- Trial name
- NCT06270784
- Testing
- Traditional Extraction, Orthodontic Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Marmara University
Nerve Injury, Laser Therapy
Histopathological, Biochemical And Electrophysiological Evaluation Of Single Or Combined Use Of Diode Laser/Steroid Treatment On Facial Nerve Injury
The objective of the study will be to investigate the effect of low-level diode laser therapy (LLLT) and steroid on facial nerve injury.
- Conditions
- Nerve Injury, Laser Therapy, Methylprednisolone, Facial Nerve Injuries
- Trial name
- facial nerve (NCT06185426)
- Testing
- Methyprednisolon and low level laser theraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Nasal Bone Fracture, Nasal Injury
Ultrasonography in the Diagnosis of Nasal Fractures
The purpose of this cross-sectional prospective observational study is to determine the efficacy of high-resolution ultrasonography in identifying and characterizing nasal bone fractures in adult patients with recent facial…
- Conditions
- Nasal Bone Fracture, Nasal Injury, Facial Injuries, Nasal Deformity, Acquired
- Trial name
- NCT06163209
- Testing
- Nasal Ultrasonography, Computed Tomography Scan of the Face
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Maxillofacial Injuries, Image Interpretation, Computer-Assisted
REDucing Unnecessary Computed Tomography Imaging for MaxillOfacial INjury
The aim is to prospectively assess the association between clinical parameters and the presence of maxillofacial fractures in trauma patients admitted to the emergency department.
- Conditions
- Maxillofacial Injuries, Image Interpretation, Computer-Assisted, Craniocerebral Trauma, Emergency Medicine
- Trial name
- REDUCTION (NCT03314480)
- Testing
- Standardized physical examination
- Where
- 4 sites in Netherlands
- Volunteers
- 1,126 people
- Sponsor
- University Medical Center Groningen
Cicatrix
Observational Study for the Long-Term Effects of a Dermal Substitute on Patients With Facial Burns.
The aim of this observational study is to investigate the long-term (between 10-20 years) results for the surgical treatment of third degree burn injury in the face and/or the neck by means of Integra® Dermal Regeneration…
- Trial name
- NCT03971968
- Testing
- Skin replacement with artificial skin
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitair Ziekenhuis Brussel
Mandibular Fractures
Focused Registry to Collect Clinical Data on the MatrixWAVE System
The goal of this registry is to evaluate the performance of the MatrixWAVE(TM) MMF system in patients suffering from non-condylar and/or condylar fractures.
- Trial name
- MatrixWAVE (NCT03405389)
- Testing
- MatrixWAVE MMF System
- Where
- 2 sites in United States, Germany
- Volunteers
- 44 people
- Sponsor
- AO Innovation Translation Center
Orbital Floor (Blow-Out) Open Fracture, Enophthalmos Traumatic
3D Printed Titanium Mesh vs Guided Autogenous Graft
In this study, the hypothesis states that there is no significant difference between specified populations. In our case, the 3D printed patient-specific titanium mesh is thought to have the same effect and results in comparison…
- Trial name
- NCT05550285
- Testing
- orbital floor recontriction
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mohammed Ghassan Mohammed Shaalan
Mandibular Fractures, Mandible Fracture
Facial iD Customized Mandible Reconstruction Plates
A retrospective post market follow up to confirm the safety and performance of Stryker's Customized Plates for Mandibular Reconstruction.
- Conditions
- Mandibular Fractures, Mandible Fracture, Mandible; Deformity, MANDIBLE
- Trial name
- NCT07245758
- Testing
- Mandibular reconstruction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stryker Craniomaxillofacial
Tooth Diseases, Piezoelectric Technique
A New Piezoelectric Technique in Third Molar Surgery
The present study aims to analyze the effect of the piezoelectric technique in third molar surgery in terms of facial swelling, trismus and pain in a split-mouth randomized controlled clinical trial
- Conditions
- Tooth Diseases, Piezoelectric Technique, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06212232
- Testing
- Piezoelectric surgery
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Zygoma Fracture
Outcomes of Zygomatic Fractures: Cross- Sectional Study
Rationale: Facial trauma is a significant event for patients, often resulting in physical and psychological consequences. Fractures in the zygomatic bone area are common due to its unique shape and positioning in the face…
- Trial name
- ZY-PROM (NCT06476340)
- Testing
- No intervention
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Facies
Facial Patterns and Masticatory Symmetries
The purpose of this study is to evaluate chewing side preference, and lateral asymmetry of occlusal contact area and bite force of individuals with different craniofacial patterns
- Trial name
- NCT01286363
- Where
- Brazil
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Corneal Perforation
Role of AS-OCT in Assessment of Corneal Perforation
Assessment of healing of thin and perforated cornea after surgical treatment by anterior segment optical coherence tomography
- Trial name
- OCT (NCT06422897)
- Testing
- anterior segment optical coherence tomography
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Minia University
Corneal Ulcer, Corneal Perforation
Topical Insulin - Utility and Results in Neurotrophic Keratopathy in Stages 2 and 3
Purpose: To evaluate the clinical outcome of patients with refractory Neurotrophic Keratopathy (NK) in stages 2 and 3 treated with topical insulin.
- Conditions
- Corneal Ulcer, Corneal Perforation, Corneal Epithelium Defect, Neurotrophic Keratitis
- Trial name
- NCT04820010
- Testing
- Topical Insulin
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Mandibular Fractures
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
- Trial name
- NCT06349135
- Testing
- Open Reduction & Internal Fixation
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Aya Ayman Ahmed
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Mandibular Fractures
Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) Plates
Mandibular fractures represent a significant portion of maxillofacial trauma, primarily resulting from motor vehicle accidents, interpersonal violence, and sports-related injuries.
- Trial name
- NCT07850570
- Testing
- Custom-Made Titanium Plate, Custom-Made PEEK Plate
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Maxillofacial Bone Defects, Alveolar Bone Atrophy
Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area.
- Conditions
- Maxillofacial Bone Defects, Alveolar Bone Atrophy, Jaw Fractures, Maxillofacial Bone Deformities
- Trial name
- NCT02293031
- Testing
- Gene-activated matrix "Nucleostim"
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- NextGen Company Limited