Clinical trials: Facial Injuries and Disorders
Eye Burns
The Role of Amniotic Membrane Transplantation in Ocular Chemical Burns
This is a randomized clinical trial study to identify the role of AMT (amniotic membrane transplantation) in treating epithelial defect, symblepharon prevention preventing corneal vascularization and opacity decreasing pain and…
- Trial name
- NCT00370812
- Testing
- amniotic membrane transplantation
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Mandibular Injuries
Accuracy and Outcome of Computer-assisted Surgery for Bony Micro-vascular Reconstruction in the Head and Neck Region
Background: Functional and aesthetic reconstruction of mandibular defects due to tumour invasion, osteoradio- or chemonecrosis or trauma are challenging.
- Trial name
- NCT03054012
- Volunteers
- 30 people
- Sponsor
- AZ Sint-Jan AV
Facial Injuries, Tissue Injury
Effect of Concentrating Endogenous Stromal Cells in the Fat Graft Using TGI Device
The overall purpose of this research is to evaluate the physical changes that occur over time after fat grafting for craniofacial trauma.
- Trial name
- AFIRM-TGI (NCT01924364)
- Testing
- Tissue Genesis Cell Isolation System™ (TGI CIS), Standard of care fat grafting
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- J. Peter Rubin, MD
TMJ Disorder
Pulsed Electromagnetic Field Therapy for TMJ Dysfunction After Facial Penetrating Injury
This study is aiming to investigate the effect of magnetic therapy in combination with traditional physical therapy on the pain and mouth opening, after facial penetrating wound injury with no facial fractures, that treated…
- Trial name
- NCT04561037
- Testing
- Pulsed Electromagnetic Field therapy (PEMFT), TMJ physical therapy program
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Kafrelsheikh University
Irregular; Contour of Cornea, Keratoconus
Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
The most common causes for irregular cornea (IC) in hospital contact lens practice are Keratoconus (KC) and related cornea thinning disorders.
- Conditions
- Irregular; Contour of Cornea, Keratoconus, Pellucid Marginal Corneal Degeneration, Injury of Cornea
- Trial name
- NCT02444923
- Testing
- Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™), Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London South Bank University
Zygomaticomaxillary Complex Fracture, Zygoma Fracture
Accuracy of Positioning Guide and Customized Plate in Zygomaticomaxillary Complex Fractures
The goal of this clinical trial is to evaluate the accuracy and stability of positioning guides and customized titanium plates in the treatment of Zygomaticomaxillary Complex (ZMC) fractures.
- Conditions
- Zygomaticomaxillary Complex Fracture, Zygoma Fracture, Zygomatic Fractures
- Trial name
- NCT07608380
- Testing
- Patient-specific positioning guide, Customized titanium plate
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Eye Injuries
A Prospective Study of Traumatic Eye Injuries in the Period From January 2022 to June 2022 in Sohag University Hospitals
Ocular trauma is one of the main causes of severe ocular morbidity. It represents a serious public health problem and leading cause of visual impairment.
- Trial name
- NCT05164588
- Testing
- Statistics
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Eye Injuries
Treatment of Radiation Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
Radiation retinopathy is a disease of the retina. It occurs in people who have received or been exposed to radiation near the eyes. The blood vessels are abnormal and may grow which lead to scarring and a loss of central vision.
- Trial name
- NCT00211367
- Testing
- Anecortave Acetate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Eye Injuries
Canadian Eye Injury Registry
The purpose of this study is to establish an eye injury registry to assess the mechanisms and outcomes of significant eye injuries occurring in Canada.
- Trial name
- CEIR (NCT01490593)
- Testing
- Public Health strategies
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mandibular Fractures
Patients 60 Years and Older Suffering From Mandibular Fractures Registry
Approximately 200 of patients of 60 years or older who present a mandibular fracture will be enrolled in this registry. All patients will be treated and followed up according to the local standard (routine) of care at around 2…
- Trial name
- NCT03849898
- Testing
- Surgery, Non-Surgical fracture treatment
- Where
- 24 sites in United States, Finland and 13 more
- Volunteers
- 25 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Orbital Fractures
The Use of 3D Printing in Orbital Fractures
The study is a prospective randomized longitudinal clinical study to compare pre-adapted patient-specific orbital implants utilizing an office-based 3-D printer versus standard non-adapted orbital implants (the latter being the…
- Trial name
- NCT03673865
- Testing
- office-based 3-dimensional printers (OB3DP), standard stock orbital plate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB)
Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa
This study consists of two phases: an Observational Phase to evaluate the natural history of ocular manifestations in subjects with Dystrophic and Junctional Epidermolysis Bullosa, followed by a Treatment Phase to assess the…
- Conditions
- Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
- Trial name
- GOTAS-ELK-EB (NCT06713434)
- Testing
- ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Fundación DEBRA Chile, Niños Piel de Cristal
Orthopedic Patients
Telemedicine and Face-to-face Consultations Diagnostic Accuracy Comparison in Orthopedic Patients
Adult patients with acute complaints related to the musculoskeletal system are prevalent and correspond to a large percentage of visits to Emergency Care Units (UPA), often performed by general practitioners.
- Trial name
- NCT04981002
- Testing
- Telemedicine Consultation with self orthopedic exam, Face-to-face Consultation
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Israelita Albert Einstein
Digital Technology, Dental Implant
Utilized Scan Body Technique For Triple Function
A triple function scan Body were done on healed dental implant, thus simplifying the workflow for full arch cases and reducing the number of visits to only 3 visits.
- Conditions
- Digital Technology, Dental Implant, Occlusion
- Trial name
- NCT05948254
- Testing
- Triple function scan body
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Eye Burns
Low Dose Doxycycline in the Treatment of Corneal Burn
To evaluate the safety and efficacy of oral low dose doxycycline in the treatment of corneal burn.
- Trial name
- NCT01886560
- Testing
- Doxycycline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Corneal Abrasion
Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion
Corneal abrasions are associated with significant discomfort during a 24-48 hrs healing phase. Current practice guidelines discourage the use of topical anesthetics in treating these patients due to concerns that these…
- Trial name
- NCT02483897
- Testing
- Tetracaine 0.5% ophthalmic drops
- Sponsor
- Queen's University
Inferior Alveolar Nerve Injuries
Orthodontic Extrusion of High Risk Impacted Mandibular Third Molar
The goal of this clinical trial is to investigate the usage of maxillary miniscrew and cross-arch elastics for the orthodontic traction of the impacted mandibular third molar in close proximity to the inferior alveolar nerve to…
- Trial name
- NCT06538688
- Testing
- Orthodontic extrusion of the impacted mandibular third molar by using the maxillary miniscrew and cross arch elastic power chain as a temporary anchorage device before extraction
- Where
- 3 sites in Egypt
- Volunteers
- 9 people
- Sponsor
- Alexandria University
Mandibular Fractures
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
- Trial name
- NCT06349135
- Testing
- Open Reduction & Internal Fixation
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Aya Ayman Ahmed
Blow-Out Fractures, Orbital Fractures
Accuracy& Orbital Volume Using Patient Specific Titanium Implant Vs Zirconia for Orbital Floor Reconstruction
Comparative study used to assess if the patient specific zirconia implant will provide better accuracy, intraoperative adaptability, precise orbital volume and soft tissue reaction with more cost effectiveness than the patient…
- Conditions
- Blow-Out Fractures, Orbital Fractures, Orbital Floor Fracture, Orbital Trauma
- Trial name
- NCT06369129
- Testing
- Orbital floor reconstruction with Patient Specific Zirconia Implant, Orbital floor reconstruction with Patient Specific Titanium Implant
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar