Clinical trials: Facial Pain
Face Pain
Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided Techniques
Botulinum toxin-A (BTX-A) prevents the release of acetylcholine in presynaptic terminals of the neuromuscular junction. It has been proposed to be effective in spastic conditions of the head and neck including oromandibular…
- Trial name
- NCT00992108
- Testing
- lidocaine, chemodenervation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Trigeminal Neuralgia, Tic Douloureux
Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain
The "Suicide Disease", Trigeminal Neuralgia (TN) is arguably caused by one of the most discrete and eloquently reversible central nervous system lesions known to the field of neurology. Recently Dr Adahan H. and Dr Binshtok A.
- Trial name
- NCT01447108
- Testing
- Low Intensity Low Frequency Surface Acoustic Wave Ultrasound (PainShield™)
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Sheba Medical Center
Trigeminal Neuralgia
Trial for Treatment Refractory Trigeminal Neuralgia
The purpose of this study is to evaluate the efficacy of BHV3000 compared to placebo for subjects with treatment refractory Trigeminal Neuralgia as measured by a 2-point or greater reduction in the average Numeric Pain Rating…
- Trial name
- NCT03941834
- Testing
- Rimegepant
- Where
- 20 sites in United States
- Volunteers
- 65 people
- Sponsor
- Pfizer
Craniomandibular Dysfunction, Orofacial Pain
Use of Electromyography With Bio-Feedback for the Treatment of Craniomandibular Disorders
The treatment of craniomandibular disorders is a challenging task. Many different treatments are yet available with occlusal splints being one of the most commonly used.
- Trial name
- NCT01949064
- Testing
- Grindcare, Michigan-type occlusal splint
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Heidelberg University
Dental Pain, Dental Anxiety
Compare the Intensity of Pain Felt by Children During the Local Anesthesia Procedure to That Perceived by the Accompanying Parent.
The goal of this observational study is to compare the intensity of pain experienced by children (aged 6 to 15) during local anaesthesia with that perceived by the parent accompanying them.
- Trial name
- ADDenT (NCT07718477)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Facial Pain, Temporomandibular Joint Disorder
Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain
This study provides a mechanism for evaluating patients for possible participation in NIDCR clinical research studies. NIDCR studies involve three major areas-pain, neurosensory mechanisms, and pain-relieving drugs-all of which…
- Trial name
- NCT00001600
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Premenstrual Syndrome
Factors Affecting Premenstrual Syndrome
Premenstrual pain syndrome is a common problem that affects many women of reproductive age. In this study, we aimed to determine whether facial massage would improve the quality of life, mood, pain and stress levels of women with…
- Trial name
- NCT07118553
- Testing
- classic facial massage
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Trabzon University
Myofacial Pain Syndrome, Clinical Decision Support
Artificial Intelligence Clinical Decision
The goal of this study is to investigate the effect of AI integration into clinical physical therapy clinical decision in improving cost effectiveness and clinical outcomes purposes of the study are: 1.
- Trial name
- AI/CDM (NCT07342790)
- Testing
- dry needling, neuromuscular facilitation (PNF) stretching, strengthening exercises (isometric & dynamic)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Oral-facial Pain
Impact of Palmitoylethanolamide (PEA) in the Management of Oro-facial Pain
Pain is the most common symptom faced by dentists, whether acute (pulpitis, acute periodontitis, post-surgical, etc.) or chronic (chronic periodontitis, muscle pain, TMJ disorders, BMS, OLP, etc.).
- Trial name
- NCT05877170
- Testing
- Palmitoyletinolamide
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Dental Pain, Anesthesia, Local
A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery
The study will be completed as a two part, prospective, single-centre, randomised controlled trial. Five volunteers (dentists) will be recruited in the first part of the study to evaluate and examine the microneedle device and…
- Trial name
- NCT02966067
- Testing
- Microneedle Device (Experimental), 30-gauge Short Hypodermic Needle
- Where
- Ireland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Impacted Mandibular Third Molar, Impacted Mandibular Third Molar Extraction
Preoperative Versus Postoperative Amoxicillin in Impacted Third Molar Surgery
This prospective observational cohort study evaluated the effects of the timing of amoxicillin use on postoperative recovery and oral health-related quality of life following impacted mandibular third molar surgery.
- Trial name
- NCT07857863
- Testing
- Amoxicillin
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Recep Tayyip Erdogan University
Trigeminal Neuralgia, Tic Douloureux
Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict
The aim of the registry is a multicenter, prospective long-term data collection of patients suspected neurovascular conflict and referred for possible microvascular decompression (Jannetta procedure).
- Conditions
- Trigeminal Neuralgia, Tic Douloureux, Facial Pain, Glossopharyngeal Neuralgia
- Trial name
- PETER registry (NCT07135024)
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 5,001 people
- Sponsor
- Gerrit A Schubert
Pain, Temporomandibular Joint Disorders
Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction
The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs…
- Conditions
- Pain, Temporomandibular Joint Disorders, Muscle Hypertonia, Myofacial Pain
- Trial name
- NCT05619380
- Testing
- physiotherapy treatment
- Where
- Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Cancer of Head and Neck, Pain, Face
Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
- Conditions
- Cancer of Head and Neck, Pain, Face, Pain, Neck
- Trial name
- NCT03894553
- Testing
- ExAblate Neuro
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Jeff Elias, MD
Dental Pain
Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
The purpose of this trial is to determine if XPF-001 is effective for the treatment of pain following third-molar/wisdom tooth extraction.
- Trial name
- NCT00954356
- Testing
- XPF-001
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Fibromyalgia
Attentional Bias Modification in Fibromyalgia Patients (ABM)
There is a growing interest in the potential benefits of attentional bias modification (ABM) training in chronic pain patients. However, studies examining the effectiveness of ABM programs in fibromyalgia patients have…
- Trial name
- ABM (NCT05905159)
- Testing
- ABM, Control
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Myalgia, Muscle Pain
The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin
The aim of the study is to evaluate the effectiveness of an aqueous solution containing CBD and CBN in the management of Facial Pain and Headache of Muscular Origin.
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT05961501
- Testing
- An aqueous solution containing CBD and CBN
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw Medical University
Dental Pain
Technology-based Distraction Techniques in Managing Children With Attention-deficit/Hyperactivity Disorder
The present study aims to assess and compare the effectiveness of different technology-based distraction techniques on pain perception and dental anxiety in children with Attention Deficit/Hyperactivity Disorder during different…
- Trial name
- NCT07411157
- Testing
- Virtual reality glasses, White noise, Basic behavior management techniques
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Temporomandibular Joint Disorders, Facial Pain
Device for Alleviating Temporomandibular Joint (TMJ) Pain
The goal of this clinical trial is to evaluate the safety and effectiveness of the investigational BTL-043 device in alleviating Temporomandibular Joint (TMJ) pain in adults aged 22 years and older.
- Conditions
- Temporomandibular Joint Disorders, Facial Pain, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT07624539
- Testing
- Treatment with BTL-043
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- BTL Industries Ltd.
Myofacial Pain Syndrome
Dry Needling and Low-Level Laser Microcurrent Electrical Stimulation for Myofascial Pain Syndrome
This study aims to evaluate the effectiveness of dry needling and Low-Level Laser Microcurrent Electrical Stimulation (LL MCES) in patients with acute upper trapezius myofascial pain syndrome (MPS) by assessing both biological…
- Trial name
- NCT07750392
- Testing
- Dry Needle, Low-Level Laser Microcurrent Electrical Stimulation
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Udayana University