Clinical trials: Facial Wrinkles
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Facial Rhytides
Reliability of the Facial Wrinkle Scale in Japanese Subjects
This study will evaluate the inter-rater and intra-rater reliability of the Facial Wrinkle Scale with Asian Photonumeric Guide (FWS-A) in Japanese subjects.
- Trial name
- NCT01600729
- Testing
- No Intervention
- Where
- Japan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Allergan
Skin Aging
Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
This research study will test how well a light therapy mask works for women with mild to moderate hyperpigmentation (brown spots) and moderate to severe facial wrinkles, as compared to a "sham" or inactive investigational light…
- Trial name
- NCT03312543
- Testing
- Active Mask
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Dynamic Wrinkles
ANTI-DYNAMIC LINE Test for Cream
The goal of this clinical trial is to find out whether a new cream (Formula# 899675 44A) can help reduce dynamic facial and neck wrinkles in young Chinese women.
- Trial name
- NCT07067073
- Testing
- Anti-Dynamic Line Cream
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Facial Wrinkles
A Double-blinded Evaluation of Safety and Efficacy of Hylaform and Hylaform Plus Compared to Zyplast.
A clinical study to investigate the safety and efficacy of Hylaform and Hylaform Plus for correction of facial wrinkles.
- Trial name
- NCT00288470
- Testing
- Hylaform, Hylaform Plus (hylan B gel)
- Sponsor
- Genzyme, a Sanofi Company
Skin Laxity, Wrinkles
Feasibility Study: Evaluation of Ulthera Versus Thermage for Treating the Face and Neck
Up to 20 subjects will be enrolled and randomly assigned to one of two treatment groups. Group A will receive Ultherapy™ on the right side of the face and neck and Thermage on the left side.
- Trial name
- NCT01713985
- Testing
- Ulthera System Treatment, Thermage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Temporary Correction of Wrinkles
Clinical Study to Evaluate the Correction of Facial Wrinkles and Folds and Safety of YVOIRE Volume Versus Perlane in Nasolabial Fold Injection
This study was purposed to evaluate the non-inferiority of YVOIRE volume, a hyaluronic acid product, in terms of correction of wrinkles and safety in nasolabial fold deep-dermal injection, compared to Perlane, the control…
- Trial name
- NCT03738007
- Testing
- HA IDF II, Perlane
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Lateral Canthal Lines (LCL), Perioral Rhytids
A Non-Interventional PMCF Study Evaluating Croma Revitalis for the Correction of Fine Lines
This study will serve to collect and analyze additional data on the use of the device croma revitalis for treatment of fine lines on the face including LCL and PR in the routine practice and as "real-world" performance.
- Trial name
- RICHER (NCT07492277)
- Where
- Austria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Correction of Nasolabial Folds and Lip Augmentation
PREVELLE Shape (CX002) Dermal Filler Protocol
The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when applied as an intradermal implant for lip…
- Trial name
- NCT00764257
- Testing
- PREVELLE Shape, Restylane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mentor Worldwide, LLC
Healthy, Sensitive Skin
In-use Tolerance and Efficacy Study Under Dermatological and Ophthalmological Controls - Face Cream, RV4983A - LA3365
Tolerance and efficacy study of an anti aging cream on 44 subjects aged between 45 and 65 years, with sensitive skin and deep wrinkles. This study is conducted as a national, monocentric, non-randomized open trial.
- Conditions
- Healthy, Sensitive Skin, Deep Wrinkles
- Trial name
- NCT07208227
- Testing
- Face Cream RV4983A LA3365
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Facial Skin Wrinkles
Safety And Efficacy Investigation Of The Effects Of ClearLift Q-Switched Nd:Yag 1064nm Laser Module In The Treatment Of Facial Skin Wrinkles
Alma Lasers ClearLift is a fractional non-ablative Q-Switched laser, allowing practitioners to use the benefits of a high intensity QS laser for the treatment of aged skin.
- Trial name
- NCT06349096
- Testing
- Alma Harmony
- Where
- Albania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Wrinkle
BTL-785F Device for Non-invasive Facial Rejuvenation in Patients Injected With Botulinum Toxin
This study will evaluate the clinical safety and the efficacy of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive facial treatment in patients injected with botulinum toxin.
- Trial name
- NCT05524766
- Testing
- BTL-785-7 Treatment
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle
Clinical and Histological Evaluation of BTL-785F Non-invasive Treatment for Facial Rejuvenation
This study will evaluate the clinical efficacy, safety and the performance of the BTL-785-2 applicator of the BTL-785F system for non-invasive treatment of facial wrinkles and correcting facial skin laxity.
- Trial name
- NCT05987917
- Testing
- BTL-785-2, No Treatment
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Wrinkles
Cryo-Touch II for the Treatment of Wrinkles
This is a prospective, non-randomized study to evaluate the performance of the MyoScience Cryo-Touch II device for the treatment of wrinkles.
- Trial name
- NCT01167140
- Testing
- Cryo-Touch II
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of DaxibotulinumtoxinA for injection (DAXI for injection) in the treatment of Glabellar Lines (GL), Dynamic Forehead Lines (FHL)…
- Trial name
- NCT04259086
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 8 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- Revance Therapeutics, Inc.
Skin Laxity, Wrinkle
Clinical Study to Evaluate the Efficacy and Safety of Matrix Pro Treatment
This is a non-randomized, multi-center, open-label, prospective clinical trial evaluating clinical treatments with the Matrix Pro Applicator for the improvement of facial and/or submental and neck laxity.
- Conditions
- Skin Laxity, Wrinkle, Skin Condition
- Trial name
- NCT06726122
- Testing
- Profound Matrix
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Skin Manifestations
Study to Evaluate the Safety and Effectiveness of GP0116
This is a prospective, randomized, evaluator-blinded, comparator-controlled, parallel group, multicenter study in the U.S. for correction of moderate to severe dynamic facial wrinkles and folds, such as nasolabial folds (NLFs).
- Trial name
- NLF (NCT05987163)
- Testing
- GP0116, Active Comparator: FDA approved dermal filler device (RHA 3)
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 186 people
- Sponsor
- Galderma R&D
Forehead Rhytides, Glabellar Rhytides
A Safety and Efficacy Study of OnabotulinumtoxinA in Forehead and Glabellar Facial Rhytides
This is a safety and efficacy study of onabotulinumtoxinA in subjects with forehead and glabellar facial rhytides (frown lines).
- Trial name
- NCT02261467
- Testing
- OnabotulinumtoxinA, Normal Saline
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 421 people
- Sponsor
- Allergan
Nasolabial Folds, Wrinkles
Non-comparative Evaluation of Facial Expressions Following Lower Face Correction Using Emervel Classic and Emervel Deep
Study is designed to characterize subject and treating investigator reported outcomes in the early post-treatment period, following bilateral correction of nasolabial folds using Emervel Classic and Emervel Deep. 1.
- Trial name
- NCT02672644
- Testing
- Emervel Classic, Emervel Deep
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Rhytides, Wrinkle
Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of facial wrinkles.
- Trial name
- NCT03831477
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Concept