Clinical trials: Facies, open to volunteers
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Face
Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults.
- Trial name
- GUM-3D (NCT07726511)
- Testing
- Hard Gum Chewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- UConn Health
General Anesthetics
Effectiveness of Facial Mask NIV in Adults Under General Anesthesia: Two-Hand C-E vs V-E Techniques
This study aims to compare two different ways doctors hold a face mask to help the participant breathe during general anesthesia. The investigators are evaluating which method, the "C-E" or the "V-E" technique, works best.
- Trial name
- VENTMASK (NCT07179432)
- Testing
- V-E facial mask ventilation maneuver, C-E facial mask ventilation maneuver
- Where
- 2 sites in Colombia
- Volunteers
- 206 people
- Sponsor
- Universidad de Antioquia
Acne Vulgaris
Facial Skin Microbiome in Patients With Moderate-to-Severe Acne Vulgaris Treated With Isotretinoin
Acne vulgaris is associated with changes in the facial skin microbiome, but longitudinal microbiome changes during isotretinoin therapy remain incompletely understood.
- Trial name
- FACEMICRO (NCT07834138)
- Testing
- ISOtretinoin 10 MG
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Pain
Validation of Faces Thermometer Scale (FTS)
The aim of this study is to evaluate validity and reliability of a novel digital pain measure tool, the Faces Thermometer Scale (FTS). Pain is commonly reported by children and adolescents undergoing dental treatment.
- Trial name
- NCT05322018
- Testing
- Faces Thermometer Scale (FTS)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Malmö University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Cutis Laxa
Effectiveness and Safety of the Ulthera® System for Skin Laxity in the Lower Face, Submentum and Neck
The purpose of this study is to demonstrate superiority of treatment with the Ulthera System compared to untreated control for the improvement of skin laxity of the lower face, submental area and neck and to demonstrate the…
- Trial name
- NCT07614997
- Testing
- Ulthera System
- Where
- 7 sites in China
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Adenotonsillar Hypertrophy
Teleconsultation vs Face-to-Face Evaluation for Perioperative Respiratory Events in Pediatric Adenotonsillectomy
The goal of this clinical trial is to assess whether preoperative anesthesia teleconsultation is at least equivalent to in-person consultation in preventing perioperative respiratory adverse events (such temporary reduction in…
- Trial name
- Teleped (NCT07175779)
- Testing
- Face-to-Face Preanesthesia Consultation, Telemedicine Preanestehsia Consultation
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Andrea Saporito
Bell's Palsy
Effects of Photobiomodulation and Electrical Stimulation Among Bell's Palsy Patients
Despite promising evidence supporting both photobiomodulation (PBM) and electrical stimulation (ES) in Bell's palsy rehabilitation, key gaps remain in the literature.
- Trial name
- NCT07266636
- Testing
- Photobiomodulation alongwith facial exercise, Electrical Stimulation alongwith facial exercise
- Volunteers
- 34 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Actinic Keratosis (AK)
Outcomes Associated With Tirbanibulin for Large Field Application on the Face in the U.S (CLEAR)
The goal of this observational study is to learn about the effectiveness of tirbanibulin among adult subjects with actinic keratosis (AK) lesions in the face.
- Trial name
- CLEAR (NCT07657988)
- Testing
- Tirbanibulin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avant Health LLC
Behavior
Influence of the 3D-sonographic Representation of the Fetal Face on the Health-conscious Behavior of Pregnant Women
Studies have shown that ultrasound examinations during pregnancy have a short-term anxiety and stress-reducing effect, without having any influence on the mother-child bond or health-conscious behavior.
- Trial name
- IN3D (NCT06901154)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Acne Vulgaris
Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Acne Patients
The combined bacteriostatic and immunomodulatory effects of erythromycin and clindamycin will be explored. Treatment effects will be extensively characterized by conventional methods including lesion counts, global assessment…
- Trial name
- NCT03883269
- Testing
- Erythromycin 4% topical gel formulation, Clindamycin 1% topical lotion formulation, 70% topical ethanol solution
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Human Drug Research, Netherlands
Actinic Keratosis
Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp
This Phase 3, randomized, multi-center, evaluator-blind, vehicle-controlled study evaluates the efficacy and safety of reformulated Levulan Kerastick (aminolevulinic acid HCl 20%) combined with photodynamic therapy (PDT) for…
- Trial name
- NCT07144345
- Testing
- Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle containing excipients only (VEH) without active ingredient, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E
- Where
- 10 sites in United States
- Volunteers
- 160 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Postherpetic Neuralgia, Peripheral Neuropathic Pain
Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.
The goal of this clinical trial is to evaluate safety and efficacy of percutaneous peripheral nerve stimulation in patients with peripheral neuropathic pain. The main questions it aims to answer are: 1.
- Conditions
- Postherpetic Neuralgia, Peripheral Neuropathic Pain, Trigeminal Neuralgia
- Trial name
- NCT06290661
- Testing
- Active electrostimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Trigeminal Neuralgia, Idiopathic, PRP
The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for the Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by brief, recurrent paroxysms of lancinating pain in the distribution of 1 or more branches of the trigeminal nerve (fifth cranial nerve [CNV]), is one of the most common, severe forms of…
- Trial name
- NCT06472323
- Testing
- PRF+PRP, PRF
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery, External
Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries
The phase-contrast MRI offers the advantage to combine precisely vascular flow measurements data with morphological images. Even if the anatomy of the external carotid artery is well known, data obtained through Phase contrast…
- Trial name
- IRM-de-FLUX (NCT02829190)
- Testing
- Magnetic Resonance Imaging (MRI),
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Facial Nerve Palsy, Corneal Exposure
Suture Lid Spring for Lid Closure in Patients With Facial Nerve Palsy
The eyelids protect the cornea and eyelid closure is essential to ocular health and clear vision. Patients with permanent Bells palsy or facial nerve palsy from other reasons such as tumours or trauma may be unable to blink and…
- Conditions
- Facial Nerve Palsy, Corneal Exposure, Paralytic Lagophthalmos
- Trial name
- SESPL (NCT06895902)
- Testing
- Polypropylene Suture Eyelid Spring for Paralytic Lagophthalmos
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Alberta
Endocrine; Deficiency, Hypothalamo-Pituitary Disorder
Brain Irradiation for Childhood Cancer - Endocrine Monitoring During the First Years
BICHE- 1: Brain Irradiation for Childhood cancer - Endocrine monitoring during the first five years is a study of endocrine monitoring after cerebral radiotherapy.
- Conditions
- Endocrine; Deficiency, Hypothalamo-Pituitary Disorder, Radiotherapy Side Effect
- Trial name
- BIChE-1 (NCT06618703)
- Testing
- Blood sample, urine sample, osteodensitometry
- Where
- 3 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Angers