Clinical trials: Faeces
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Gastro-Intestinal Disorder
Healthy Stool Volunteer Donors for Fecal Microbiota Transplantation Trials
Currently, ANSM recommendations govern FMT (Fecal Microbiota Transplantation) in clinical trials. The collection and validation of these stool donations as part of the trials is complex and not very efficient.
- Trial name
- VIOLONSEL (NCT06478823)
- Testing
- Stools donation
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colorectal Cancer
Screening for Colorectal Cancer With FOBT, Virtual Colonoscopy and Optical Colonoscopy. A Randomized Clinical Trial in the Florence District
RATIONALE: Computed tomographic colonography (CTC) has proven to be accurate in detecting colorectal neoplasms and may be a primary test in colorectal cancer screening.
- Trial name
- SAVE (NCT01651624)
- Testing
- Invitation to screening
- Where
- Italy
- Volunteers
- 16,087 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention and Research Institute, Italy
Health Behavior, Personal Satisfaction
Effect of InFat™ Product on Stool Biochemistry and Stool Characteristics in Formula-fed Term Infants in China
The purpose of this study is to determine the effect of infant formula with high percentage of palmitic acid at the sn-2 position (InFat™) on improving fat absorption and general gastrointestinal tolerance in Chinese formula-fed…
- Trial name
- NCT01373541
- Testing
- InFat™ based infant formula, Standard vegetable oil based infant formula
- Where
- China
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Enzymotec
Antiphospholipid Syndrome (APS)
Pilot Study of Gut Commensals in Antiphospholipid Syndrome
The purpose of this study is to explore if certain commensals within the gut microbiota (the collection of all microbes that live inside the gut) correlate with autoantibodies in the autoimmune clotting disorder called…
- Trial name
- NCT01787305
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy Subjects
Combination of Probiotic and Calcium in Healthy Adults
The study was conducted to investigate the effect of the probiotic L. paracasei LPC 37 alone or in combination with a calcium supplement of the human microbiota and further physiological parameters.
- Trial name
- NCT01033461
- Testing
- calcium and probiotic, probiotic
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Jena
Constipation
Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects
The objective of this study is to evaluate if consumption of fermented milk containing Lactobacillus casei strain Shirota has an impact on stool consistency, stool frequency, constipation-related symptoms, and quality of life in…
- Trial name
- NCT01375712
- Testing
- Fermented milk containing Lactobacillus casei strain Shirota
- Where
- Germany
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Yakult Honsha Co., LTD
Constipation
Effectiveness of Partially Hydrolyzed Guar Gum in Improving Fecal Characteristics in Long Term Care Facility Residents
Partially hydrolyzed guar gum (PHGG) is a vegetal, water soluble, non-viscous, non-gelling dietary fiber that is derived from guar gum, a water-soluble, viscous, gelling polysaccharide found in the seeds of Cyamopsis…
- Trial name
- NCT05037565
- Testing
- Partially hydrolyzed guar gum
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Inflammatory Bowel Disease (IBD), Crohn's Disease (CD)
Faecal Calprotectin as a Potential Non-invasive Inflammatory Marker in Pregnancy and Inflammatory Bowel Disease
When women with rheumatoid arthritis become pregnant 75% of them will go into remission, despite stopping medication. This phenomenon is not well understood and is not seen in other inflammatory conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Crohn's Disease (CD), Ulcerative Colitis (UC), Pregnancy
- Trial name
- PREGCAL (NCT02778464)
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Hepatic Encephalopathy, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for the Treatment of Refractory Hepatic Encephalopathy After TIPS Surgery
This is a single-center, prospective, open-label, parallel-group exploratory clinical study designed to evaluate the safety and preliminary efficacy of fecal microbiota transplantation combined with standard medical therapy in…
- Conditions
- Hepatic Encephalopathy, Fecal Microbiota Transplantation, TIPS, Refractory Hepatic Encephalopathy
- Trial name
- NCT07683936
- Testing
- Fecal Microbiota Transplantation, Rifaximin、Lactulose, Dietary Fiber Prebiotic
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Fecal Incontinence, Urinary Incontinence
First Time Mothers and Anal Incontinence Six Years Postpartum
Previous studies show that incontinence is relatively common during pregnancy and after delivery. Experiencing incontinence during pregnancy or in the first year after delivery increases the risk of long term incontinence.
- Conditions
- Fecal Incontinence, Urinary Incontinence, Quality of Life
- Trial name
- FiTMAI6 (NCT02792244)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Clostridium Difficile Infections
Safety Registry of a Fecal Microbiota Transplant Cohort
Clostridium difficile infection (CDI) is a major cause of infectious diarrhea and the most important cause of nosocomial diarrhea. Recurrent forms are a major problem with this infection.
- Trial name
- COSMIC-FMT (NCT06311006)
- Where
- France
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Clostridium Difficile Colitis
Stool Transplant in Pediatric Patients With Recurring C. Difficile Infection
The incidence of C. difficile infection (CDI) has alarmingly increased over the past several years and the affected population has expanded to include those previously at low risk, such as children.
- Trial name
- NCT01972334
- Testing
- FMT
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Pregnancy
Effect of Pilates and Kegel Exercises During Pregnancy
Urinary incontinence and fecal incontinence are common health problems in the postpartum period because of their effect on daily life and are likely to reduce quality of life.
- Trial name
- NCT06869538
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hitit University
Atopic Dermatitis
Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis
Prospective single-blinded placebo-controlled cross-over study, among adult patients suffering from moderate-to-severe atopic dermatitis (AD), insufficiently responsive to topical and systemic treatment.
- Trial name
- NCT04613037
- Testing
- Fecal Microbial Transplantation
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Irritable Bowel Syndrome, Dysbiosis
Fecal Microbiota Transplantation and ACHIM for Manipulating Gut Microbiota in IBS Patients
The double-blinded placebo-controlled study compares the effect of fecal microbiota transplantation vs. Anaerobically Cultivated Human Intestinal Microbiota (ACHIM) or placebo (own feces) on manipulating the gut microbiota in…
- Trial name
- NCT05088434
- Testing
- Anaerobically Cultivated Human Intestinal Microbiota (ACHIM), Donor fecal microbiota transplantation
- Where
- Norway
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Gut Microbiome, Buffer
PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals
The study aims to assess the effectiveness of various commercial and non-hazardous buffers for the storage of human gut fecal samples over time.
- Conditions
- Gut Microbiome, Buffer, Methodology Study, Fecal Microbiota
- Trial name
- PROTEGI (NCT06423508)
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Ulcerative Colitis, Irritable Bowel Syndrome
Fecal Microbiota Transplantation for Health Improvement (TFM3)
Search for mechanisms of the effect of fecal transplantation on a healthy organism and various nosological forms.
- Conditions
- Ulcerative Colitis, Irritable Bowel Syndrome, Crohn Disease, Irritable Bowel
- Trial name
- TFM3 (NCT04011943)
- Testing
- Fecal Microbiota Transplantation
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal Research and Clinical Center of Physical-Chemical Medicine
Infectious Disease of Digestive Tract
Autologous Fecal Therapy
Ten healthy volunteers will be recruited to receive either an autologous stool transplant or a saline enema to determine if autologous fecal microbiota therapy will be able to rapidly, and safely, restore a patient's fecal…
- Trial name
- NCT02046525
- Testing
- Autologous fecal microbiota therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colorectal Cancer, Colon Cancer
Pilot Study of Colon Cancer Screening Tests
Colon cancer is the second leading cause of cancer death in North America. These deaths are preventable with proper screening. Fecal occult blood testing, virtual colonoscopy, and standard (optical) colonoscopy are all options…
- Conditions
- Colorectal Cancer, Colon Cancer, Adenomatous Polyps
- Trial name
- NCT00865527
- Testing
- Fecal occult blood test, Virtual colonoscopy, Optical colonoscopy
- Where
- Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation