Clinical trials: Failure to Rescue
Postoperative Complications, Patient Care Team
Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population
High risk surgical patients are subject to complications that impact rehabilitation time, overall mortality and costs. This project proposes the creation of a post-surgery care pathway called Extended Care in High-Risk Surgical…
- Trial name
- EXCARE (NCT04187664)
- Testing
- Postoperative Monitoring, High-sensitivity cardiac troponin testing
- Where
- Brazil
- Volunteers
- 1,720 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anastomotic Leak, Colorectal Cancer
Predictors of Rescue Surgery, Mortality, and Permanent Stoma After Anastomotic Leak Following Colorectal Cancer Resection
Anastomotic leakage is a serious complication following colorectal cancer resection and may result in emergency reoperation, severe sepsis, death, loss of the colorectal anastomosis, and formation of a long-term or permanent…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Colon Cancer, Postoperative Complication
- Trial name
- leak predictor (NCT07725692)
- Where
- Egypt
- Volunteers
- 3,200 people
- Sponsor
- Alexandria University
HIV
Antiretroviral Resistance Detection by Ultrasensitive Pyrosequencing of the HIV-1 Genome and Virological Response to Antiretroviral Rescue Treatment
This study aims to analyze the association between the baseline detection of resistance mutations through Ultra deep Sequencing (UDS) and the virological outcome of salvage antiretroviral therapy, in comparison with conventional…
- Trial name
- NCT01346878
- Where
- 4 sites in Spain
- Volunteers
- 143 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Sepsis, Renal Failure
The Prevention of Failure to Rescue Using Early Warning Scoring
The purpose of this study is to assess if, compared with standard paper-based systems, an automated Early Warning System (EWS) resident in a spot check patient monitor, can help to identify deteriorating patients.
- Conditions
- Sepsis, Renal Failure, Pulmonary Edema, Cardio-pulmonary Arrest
- Trial name
- VitalCare (NCT01197326)
- Testing
- use of the MP5 EWS patient monitor
- Where
- Australia
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Philips Healthcare
Postoperative Complications
QoR-9 AS predicTor of postopErative Complications
Aim of the study is to evaluate, whether the self administered quality of recovery (QoR-9) questionnaire can predict postoperative complications after non-cardiac surgery and whether preoperative risk estimates can be improved by…
- Trial name
- NCT03669419
- Testing
- QoR 9 Questionnaire
- Where
- Germany
- Volunteers
- 3,854 people
- Sponsor
- Technical University of Munich
Pancreas Neoplasm
Postoperative Outcomes After Partial Duodenopancreatectomy Versus Total Pancreatectomy
The goal of this observational study is to compare short-term outcomes after partial pancreatoduodenectomy and total pancreatectomy in adults undergoing elective surgery for pancreatic or periampullary neoplasms in Switzerland.
- Trial name
- NCT07831694
- Volunteers
- 3,602 people
- Sponsor
- Cantonal Hospital of St. Gallen
Bronchiolitis, Respiratory Syncytial Virus (RSV)
High Flow Nasal Cannula Therapy in Bronchiolitis : Early vs Rescue
The enrolled RSV-bronchiolitis patients will be randomized into two arms , the early HHHFNC group and the standard therapy group with rescue HHHFNC to study the efficacy of this treatment.
- Trial name
- NCT03095495
- Testing
- Heated Humidified High Flow Nasal Cannula, Standard Therapy (Low Flow Nasal Cannula)
- Where
- Qatar
- Volunteers
- 28 people
- Sponsor
- Hamad Medical Corporation
Acute Mechanical Ventilatory Failure
Rescue High Frequency Oscillatory Ventilation in Newborns Who Do Not Respond to Conventional Ventilation
Although High Frequency Oscillatory Ventilation (HFOV) has been used in case of unresponsive to conventional mechanical ventilation both in children and newborns, there is no data on its success and the factors that affect its…
- Trial name
- RescueHFO (NCT02752438)
- Testing
- HFOV
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ankara University
Failure to Rescue, Emergencies
Rescue for Emergency Surgery Patients Observed to uNdergo Acute Deterioration
This is a Five Year programme designed to identify and evaluate human factors interventions to improve the response to patients deteriorating following emergency surgery.
- Trial name
- RESPOND (NCT04919720)
- Testing
- FRAM Model and Human Factors/Quality Improvement Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 9,064 people
- Sponsor
- University of Oxford
Surgery, Failure to Rescue
'5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation
'Failure to rescue' describes the preventable death of a patient following the absence of timely identification and treatment of a complication after surgery.
- Trial name
- NCT06997328
- Testing
- Implementation of the '5 Rs to Rescue'
- Where
- South Africa
- Volunteers
- 6,000 people
- Sponsor
- University of Cape Town
Hospital Acquired Condition
(CONCERN) Clinical Decision Support (CDS) System
There are patients who die or have a bad outcome in the hospital and this could be prevented. Data in the nurses' notes could be used by computers to tell the rest of the care team that a patient is not doing well and that they…
- Trial name
- NCT03911687
- Testing
- CONCERN CDS system notification
- Where
- 4 sites in United States
- Volunteers
- 60,893 people
- Sponsor
- Columbia University
Fanconi's Anemia, Pancytopenia
Gene Therapy for the Treatment of Fanconi's Anemia Type C
Fanconi's Anemia is an inherited disorder that can produce bone marrow failure. In addition, some patients with Fanconi's anemia have physical defects usually involving the skeleton and kidneys.
- Trial name
- NCT00001399
- Testing
- Transduced CD34+ Cells
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Surgery--Complications
Cognitive Aids for the Management of Deteriorating Surgical Patients
Background and Goal of Study: Adherence to best practice management of emergencies improves through the use of cognitive aids. Aim of this study was to develop and validate cognitive aids for management of deteriorating surgical…
- Trial name
- CAMDS (NCT03812861)
- Testing
- CAMDS bundle
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)