Clinical trials: Failure to Thrive
Growth Failure, X-linked Severe Combined Immunodeficiency (XSCID)
Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1
This study will evaluate the safety and effectiveness of insulin-like growth factor-1 (IGF-1) to treat patients with X-linked severe combined immunodeficiency (XSCID).
- Conditions
- Growth Failure, X-linked Severe Combined Immunodeficiency (XSCID), Growth Hormone Resistence
- Trial name
- NCT00490100
- Testing
- Increlex
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Growth Disorders, Growth Failure
Is There a Microbiome Associated With Poor Growth in Preterm Infants?
This study evaluates the relationship between growth and stool microbiota in premature infants.
- Conditions
- Growth Disorders, Growth Failure, Prematurity
- Trial name
- NCT03761498
- Testing
- Caloric Requirement
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Texas Southwestern Medical Center
Growth Failure
Safety Study of Infant Formula With Partially Hydrolized Whey
The study will be a randomized, double-blind, prospective trial. Newborn infants (enrollment age 0-14 days) will be assigned randomly to receive one of two products, provided in identical packages except for the lid color.
- Trial name
- NCT00548106
- Testing
- partially hydrolyzed whey, Nan HA
- Where
- Israel
- Sponsor
- Soroka University Medical Center
Growth Failure
Human Milk Fortification With Adjustable Versus Targeted Method
Research question: Do preterm infants born <1250 g achieve better weight gain with targeted fortification compared with the adjustable fortification of human milk? Hypothesis: Targeted fortification of human milk results in…
- Trial name
- FAT (NCT04809350)
- Testing
- Adjustable Human Milk Fortification, Targeted Human Milk Fortification
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Calgary
Hypoplastic Left Heart Syndrome, Growth Failure
Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants
The purpose of the study is to determine if a continuous feeding regimen as compared to an intermittent bolus feeding regimen leads to improved weight gain in infants with hypoplastic left heart syndrome (HLHS) after stage 1…
- Trial name
- NCT02657629
- Testing
- Continuous Feeding Regimen, Intermittent Bolus Feeding Regimen
- Volunteers
- 28 people
- Sponsor
- Columbia University
Infant,Premature, Bronchopulmonary Dysplasia
Enteral Zinc to Improve Growth in Infants at Risk for Bronchopulmonary Dysplasia
Multiple factors contribute to growth failure in infants with BPD, including poor nutrient stores, inadequate intake, increased losses, and increased needs.
- Conditions
- Infant,Premature, Bronchopulmonary Dysplasia, Growth Failure
- Trial name
- NCT03532555
- Testing
- Zinc Acetate, No supplemental zinc
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Utah
Growth Failure
High vs Standard Energy Children's Drink Study
This study is a pilot trial investigating the effects of a high energy drink for children, in comparison to standard energy drink for children.
- Trial name
- NCT02419599
- Testing
- HE ONS, SE ONS
- Volunteers
- 51 people
- Sponsor
- Nutricia UK Ltd
Prematurity; Extreme, Failure to Thrive in Newborn
Targeted Fortification of Donor Breast Milk in Preterm Infants
This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants.
- Conditions
- Prematurity; Extreme, Failure to Thrive in Newborn, Growth Retardation, Growth Failure
- Trial name
- NCT04294368
- Testing
- Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid, Similac Liquid Protein Fortifier, Nestle Microlipid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Electrolyte Depletion, Stoma Ileostomy
Evaluation of the Normal Range of Urinary Sodium Levels in Healthy Newborn Babies
Oral sodium supplementation is currently administered in cases of poor weight gain in infants particularly in patients who have undergone gastrointestinal surgical procedures.
- Conditions
- Electrolyte Depletion, Stoma Ileostomy, Stoma Colostomy, Growth Failure
- Trial name
- USALTI (NCT03016195)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Growth Failure, Preterm Birth
Impact of Colostrum Oropharyngeal Immunotherapy on Postnatal Growth in Preterm Infants
The goal of this clinical trial is to ascertain whether oropharyngeal administration of colostrum contributes to postnatal growth in very preterm infants (those born before 32 weeks of gestation).
- Conditions
- Growth Failure, Preterm Birth, Microbiota
- Trial name
- IOCOIOPGIPI (NCT07082881)
- Testing
- Colostrum, Normal Saline
- Volunteers
- 220 people
- Sponsor
- Suqian First Hospital
Cystic Fibrosis, Failure to Thrive
Clinical Study With an Enteral Formula With Symbiotic and DHA for Malnourished Children
The purpose of this study is to determine whether a nutritional supplement is effective in the treatment of malnutrition in pediatric patients with failure to thrive or cystic fibrosis.
- Conditions
- Cystic Fibrosis, Failure to Thrive, Malnutrition
- Trial name
- VITJUNIOR (NCT02128984)
- Testing
- Symbiotic Formula with DHA and antioxidants, Standard Formula
- Where
- 8 sites in Peru, Spain
- Volunteers
- 109 people
- Sponsor
- Laboratorios Ordesa
Cow Milk Protein Sensitivity, Tolerance
Tolerance of Infants With Cow's Milk Protein Allergy to Extensively Hydrolyzed Rice Protein or Casein Infant Formulas
The objective of this double blinded randomized study is to assess the tolerance of two extensively protein hydrolyzed infant formulas, one based on rice protein and the other one on casein, at introduction, and after 3 months of…
- Conditions
- Cow Milk Protein Sensitivity, Tolerance, Growth Failure
- Trial name
- JUNGLO (NCT01909661)
- Testing
- Damira/Celia peptide hydrolyzed casein, Picot riz/Celia rice/Sanutri arroz
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Lactalis
Other Preterm Infants, Transitory Neonatal Electrolyte Disturbance
Clinical Tolerance of Numeta 13%
Numeta G13% is a triple chamber bag including amino acids plus electrolytes, glucose and lipids, dedicated for parenteral nutrition in preterm newborn infants when oral/enteral nutrition is not possible, insufficient or contra…
- Conditions
- Other Preterm Infants, Transitory Neonatal Electrolyte Disturbance, Disorder of Mineral Metabolism, Failure to Thrive
- Trial name
- BAXTERULG2 (NCT01772927)
- Testing
- Parenteral Nutrition
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University of Liege
Growth Hormone Deficiency (GHD)
Treatment of Children With Insufficient Secretion of Growth Hormone
The purpose of this study is to compare a new weekly administered growth hormone preparation with standard daily treatment in children with insufficient secretion of growth hormone
- Trial name
- BPLG-004 (NCT00271518)
- Testing
- growth hormone (somatropin)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- LG Life Sciences
Growth Failure in Medically Complex Infants, Growth Failure
Medical Nutrition Therapy for Medically Complex Infants in the Pediatric Outpatient Setting
The purpose of this study is to compare standardized nutrition therapy provided by a registered dietitian (RD) at regularly scheduled intervals to usual care in terms of the ability to improve growth parameters in medically…
- Conditions
- Growth Failure in Medically Complex Infants, Growth Failure, Malnutrition in Medically Complex Infants, Malnutrition
- Trial name
- NCT03522558
- Testing
- Standardized Medical Nutrition Therapy, Usual Care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Premature Birth, Infant, Extremely Low Birth Weight
Additional Protein Fortification in Extremely Low Birth Weight Infants
Postnatal growth is a crucial in premature infants as it could be correlated with the long-term cognitive development. Optimal nutritional care is required to reduce the initial weight loss and further growth deficit.
- Conditions
- Premature Birth, Infant, Extremely Low Birth Weight, Growth Failure
- Trial name
- PROTSUP (NCT02515266)
- Testing
- nutrition: protein intake
- Volunteers
- 152 people
- Sponsor
- Hôpital de la Croix-Rousse
Growth Failure, Chronic Liver Disease
Increlex Treatment of Children With Chronic Liver Disease and Short Stature
A major consequence of chronic liver disease in childhood is growth failure. This is because a chemical essential for growth called growth factor is created in the liver.
- Trial name
- NCT01314508
- Testing
- Increlex
- Sponsor
- University of California, Los Angeles
Hospitalized Cases of Angioneurotic Oedema, Pneumonia
Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
The purpose of this study is 1. To describe patient characteristics and drug usage among children that are prescribed esomeprazole for the first time and to compare them with patients who are prescribed other proton pump…
- Conditions
- Hospitalized Cases of Angioneurotic Oedema, Pneumonia, Gastroenteritis, Failure to Thrive
- Trial name
- NCT01338363
- Where
- Netherlands
- Volunteers
- 23,470 people
- Sponsor
- AstraZeneca
Faltering Growth, Failure to Thrive
Leveraging Optimal Tolerance in Undernourished Infants to Support Growth
The goal of this study is to learn if InfaCore (IC) an energy and nutrient dense formulation (ENDF) can improve growth and tolerance in infants with or at risk of growth faltering when fed IC.
- Trial name
- LOTUS (NCT07549360)
- Testing
- Infant Formula
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Dutch Medical Food