Clinical trials: Familial Aortopathies
Magnetic Resonance Imaging, Pregnancy
Non-contrast 3D MR Angiography for Assessment of the Thoracic Aorta in Pregnancy
Introduction: Native magnetic resonance angiography (MRA) is recommended to assess the thoracic aorta during pregnancy, avoiding the risks of ionising radiation and contrast agent administration.
- Trial name
- NCT02793570
- Testing
- observational
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Familial Aortopathies
Familial Aortopathies and Cellular Exploration
The prevalence of hereditary aortic disease (HTAD), responsible for aneurysm or dissection, is estimated at 25%. Mutations in the ACTA2 gene represent the main cause of non-syndromic forms (10-21%).
- Trial name
- FACE (NCT05401500)
- Testing
- blood sample
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Aortopathies, Thoracic Aortic Aneurysm
Pathogenetic Basis of Aortopathy and Aortic Valve Disease
The main purpose of this study is to define the complex genetic and pathogenic basis of thoracic aortic aneurysm (TAA) and other forms of aortopathy and/or aortic valve disease by identifying novel disease-causing genes and by…
- Conditions
- Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease
- Trial name
- TAA (NCT03440697)
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Yale University