Clinical trials: Family Medicine
Atherosclerosis, Cardiovascular Disease
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.
- Conditions
- Atherosclerosis, Cardiovascular Disease, Hypercholesterolemia
- Trial name
- HEART-3 (NCT07839936)
- Testing
- VERVE-102
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Verve Therapeutics, Inc.
Hypercholesterolemia, Familial Hypercholesterolemia
A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)
This study is a non-interventional (observational) study in Japan to confirm the safety and efficacy of Zetia when administered alone or in combination with other lipid-lowering drugs in daily medical practice throughout a…
- Conditions
- Hypercholesterolemia, Familial Hypercholesterolemia, Homozygous Sitosterolemia
- Trial name
- NCT00705211
- Testing
- Ezetimibe, Ezetimibe + other lipid-lowering medication(s)
- Volunteers
- 1,794 people
- Sponsor
- Organon and Co
Cardiovascular Risk Factors, Coronary Disease
CPR Education Via a Mobile Application Compared to VSI Kit
Prompt delivery of cardiopulmonary resuscitation (CPR) is a crucial determinant of survival for many victims of sudden cardiac arrest (SCA), yet bystander CPR is provided in less than one third of witnessed SCA events.
- Conditions
- Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
- Trial name
- NCT02548793
- Testing
- Education: CPR Training via Mobile App, Education: CPR Training using the CPR Anytime VSI Kit
- Where
- 7 sites in United States
- Volunteers
- 1,679 people
- Sponsor
- University of Pennsylvania
Primary Pulmonary Hypertension
Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil
The primary objective of this study is to evaluate the long-term safety of LIQ861 in patients with pulmonary arterial hypertension (PAH).
- Trial name
- NCT03992755
- Testing
- LIQ861 Inhaled Treprostinil
- Where
- 25 sites in United States
- Volunteers
- 92 people
- Sponsor
- Liquidia Technologies, Inc.
Maternal Behavior, Depression
Interconception Care at the University of Mississippi Medical Center
This model will utilize tools from the IMPLICIT (Interventions to Minimize Preterm and Low Birth Weight Infant through Continuous Quality Improvement Techniques) Network (collaboration of academic family medicine providers).
- Trial name
- NCT03024385
- Testing
- Well Child Visits
- Where
- United States
- Volunteers
- 1,625 people
- Sponsor
- University of Mississippi Medical Center
Psychotic Disorders
Family Perspectives:Treatment of Psychiatric Illnesses With Atypical Long Acting Injectable Antipsychotic Medication
Patients who have schizophrenia, schizoaffective disorder, a psychotic disorder, and are being treated with a medication called Risperidone Long Acting Injectable medication or another antipsychotic medication are candidates for…
- Trial name
- NCT00287027
- Testing
- Risperdal Long Acting Injectable Antipsychotic Medication
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Alliance on Mental Illness New Hampshire
Medically Unexplained Symptoms, Sense of Coherence
Sense of Coherence and Empowerment at Patients With MUPS
This is a study on Metacognitive therapy in general practice in Norway. The intervention is a small pilot study to examine whether Metacognitive therapy is feasible in an ordinary general practice.
- Trial name
- NCT05121922
- Testing
- Metacognitive Therapy
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oslo
NAFLD
Probiotic Supplementation IN NAFLD Patients
this study aimed to evaluate the effectiveness of Probiotics supplementation (lactobacillus) on NAFLD fibrosis score.
- Trial name
- NCT06074094
- Testing
- Control Test
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Diabetes Mellitus Type II,
E-health Care Process Support for Diabetes Type II Patients
The purpose of the study is to clinically evaluate a new approach to treatment of patients with diabetes mellitus type II by using specially developed mobile-internet software solution.
- Trial name
- EHDI (NCT01566981)
- Testing
- Computerised support to the Diabetes type II patients
- Where
- 2 sites in Slovenia
- Volunteers
- 120 people
- Sponsor
- University of Primorska
Osteoarthritis, Knee
Implantation of Gold Beads to Relieve Discomfort From Knee Osteoarthritis
The purpose of this study is to determine whether implanting gold beads extraarticularly in five acupuncture-points around a knee improves pain, stiffness and function in patients with knee osteoarthritis.
- Trial name
- NCT00487370
- Testing
- Implantation of gold beads around a knee through needles
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Research Unit Of General Practice, Copenhagen
Depression, Unipolar, Cardiovascular Diseases
Lifestyle InterVEntion Study in General Practice: LIVES - GP
Patients with depression are at a substantially increased risk of chronic physical disease including cardiovascular disease. This may be attributed primarily to an unhealthy lifestyle related to their disorder.
- Trial name
- LIVES-GP (NCT06286345)
- Testing
- GLI-LEEF
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- University Medical Center Groningen
HIV, PrEP
Bringing Medicines for HIV Prevention to a Family Planning Clinic
The goal of this clinical trial is to understand what patients and physicians think about providing medications to prevent HIV transmission to patients in a family planning clinic.
- Trial name
- NCT06930508
- Testing
- Patient participant screening, Physician participant training
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Parkinsonian Syndrome
A Study of Brain Imaging With Nuclear Medicine Technology in Individuals With and at Risk for Parkinson's Disease
This study involves study participants who have been clinically diagnosed with parkinsonian syndrome or who are at-risk for parkinsonian syndrome, have a family history of parkinsonian syndrome or exposure to environmental toxins…
- Trial name
- NCT00117819
- Testing
- [123I]ß CIT and SPECT imaging
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking Cessation, Smoking Cessation Counselling
New Smoking Cessation Intervention in Primary Care - a Randomized Controlled Trial
Cigarette smoking remains the leading modifiable risk factor for lung cancer4 and 16 other types of cancer, as well as chronic cardiovascular and pulmonary diseases.
- Trial name
- NCT07900724
- Testing
- WillQuit App, Smoking cessation standard treatment,
- Where
- Norway
- Volunteers
- 620 people
- Sponsor
- Helse Nord-Trøndelag HF
Asthma
CARE - Quality Improvement in Asthma Secondary Prevention in Primary Care, Through Delegation of Consultations to the Nurse.
Quality Improvement in Primary Care: delegation of check-ups to nurses in general practice
- Trial name
- NCT00714038
- Where
- 93 sites in Denmark
- Volunteers
- 2,122 people
- Sponsor
- AstraZeneca
COPD, Spirometry
Evaluation of a Mobile Application to Facilitate the Interpretation of Spirometry by Family Physicians and Residents
Problematic: Spirometry is used to objectify the obstructive syndrome defining chronic obstructive pulmonary disease (COPD). However, this test remains underused in the primary care.
- Conditions
- COPD, Spirometry, Mobile Application
- Trial name
- NCT03206606
- Testing
- SPIRO
- Where
- 8 sites in Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Laval University
Substance Use, Delinquency
Family-Based Juvenile Drug Court Services
The objective of the proposed study is to adapt and implement an efficacious adolescent substance abuse treatment, Multidimensional Family Therapy (MDFT), within the juvenile drug court service system.
- Trial name
- JDC (NCT01668303)
- Testing
- Miami Juvenile Drug Court-MDFT, Miami Juvenile Drug Court -TAU
- Where
- 4 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dementia, Dementia Alzheimers
Implementation of a Diagnostic Decision-aid for People With Memory Complaints and Their General Practitioners
In a mixed-methods design the investigators will study decision making processes and experiences regarding a diagnostic trajectory before and after the introduction of a patient decision aid for people with memory complaints…
- Conditions
- Dementia, Dementia Alzheimers, Dementia, Mild
- Trial name
- S-DeciDeD (NCT04531956)
- Testing
- Diagnostic decision aid s-decided
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University
COPD (Chronic Obstructive Pulmonary Disease)
Reduced COPD Related Utilization of Healthcare Services and Increased Social Activities by Patients Offered a 24/7 Accessible Telehealth Service Based on the Epital Care Model.
The purpose of this study (The TEMOKAP study) is to investigate whether home-based treatment with telemedicine and support from healthcare professionals can prevent acute exacerbations of COPD and avoid acute hospital admissions…
- Trial name
- TEMOKAP (NCT06988566)
- Testing
- Intervention Group
- Where
- Denmark
- Volunteers
- 184 people
- Sponsor
- ECM Klinikken APS