Clinical trials: Fascial Closure
Hernia, Ventral
Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial
This study is comparing the outcomes patients undergoing LVHR, PFC as opposed to a bridged repair with assessment of patient reported satisfaction and function at 6 months of follow-up.
- Trial name
- NCT02363790
- Testing
- LVHR PFC, Bridging LVHR
- Where
- 5 sites in United States
- Volunteers
- 189 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ventral Hernia
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
A ventral hernia happens when the muscles in the front of your belly become weak and let organs push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems.
- Trial name
- NCT07226791
- Testing
- AGN-151607-DP
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- AbbVie
Parastomal Hernia
Fascial Defect Closure for Minimally Invasive Parastomal Hernia Repair
Fascial closure was not originally a routine component of minimally invasive parastomal hernia repairs, but several recent advancements have made fascial closure more common in this context.
- Trial name
- NCT05514600
- Testing
- closure of parastomal hernia fascial defect
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Hernia, Abdominal
Efficacy Study to Evaluate Laparoscopic Fascial Closure Device
During any minimally invasive surgery case, 5-25mm size incisions need to be made to gain access to the abdomen. One of the most difficult, time-consuming, and sometimes unreliable parts of the case is closing these incisions…
- Trial name
- NCT01024296
- Testing
- Port Close
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Stanford University
Surgical Site Infection
Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for perforated viscera.
- Trial name
- NCT06129773
- Testing
- antibiotic coated vicryl used for fascial closure
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Adeel Ashiq
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Cholecystolithiasis
Nasr Fascial Closure: A Novel Device for Fascial Closure in Laparoscopic Surgery
The study will investigate the efficacy and safety of a new fascial closure device "Nasr Fascial Closure Device" compared to the Karl Storz Berci Fascial Closure Device 26173AM.
- Trial name
- NCT06036303
- Testing
- Nasr fascial closure device, Berci Fascial Closure Device
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- ClinAmygate
Fascial Closure
Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy
The primary objective of this study is to identify the optimal method of fascial closure of a laparotomy incision in high risk patients for intra-abdominal complications.
- Trial name
- NCT02145052
- Testing
- Continuous suture, Interrupted suture
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Massachusetts General Hospital
Ventral Hernia, Abdominal Hernia
A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique
Ventral hernias form when there is a loss of integrity of the abdominal wall muscles. Abdominal hernias can expand and can cause severe pain as the abdominal wall weakens.
- Trial name
- NCT05606757
- Testing
- BOTOX Dose A, BOTOX Dose B, BOTOX Dose C
- Where
- 2 sites in United States
- Sponsor
- AbbVie
Incisional Hernia Repair, Ventral Incisional Hernia
Standard Closure vs. Integrated Mesh-Fascial Closure (IMFC) for Incisional Hernia Repair
This study compares two surgical techniques for closing the abdominal wall in adult patients who have an incisional hernia (a weakness or opening in a previous surgical incision) or who require prophylactic mesh placement during…
- Trial name
- IMFC (NCT07843225)
- Testing
- Integrated Mesh-Fascial Closure, Standard Fascial Closure with Mesh
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hospital Zonal General De Agudos Mario V Larrain
Pilonidal Sinus
GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Surgical treatment is still gold standard for pilonidal sinus disease. Several surgical techniques have been proposed to treat this disease in the last two decades.
- Trial name
- GLUE (NCT03914729)
- Testing
- Primary Closure, Gluteus Maximus Fascia Plasty Flap
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Russian Society of Colorectal Surgeons
Wound Infection, Incisional Hernia
PDS*Plus and Wound Infections After Laparotomy
The aim of this study is to ascertain if the use of PDS plus® reduces the number of wound infections and incisional hernia after midline and transverse laparotomy comparing to polyglactin suture.
- Trial name
- PDS*plus (NCT00998907)
- Testing
- PDS plus, PDS II
- Where
- Germany
- Volunteers
- 1,042 people
- Sponsor
- University Hospital, Saarland
Primary Median Laparotomy
Multi-center Study to Evaluate the Safety and Efficacy of Aesculap MonoMax® for Abdominal Wall Closure
MonoMax will be used for a continuous all-layer (except skin) suture to close abdominal wall after midline incision. The primary objective of this trial is to demonstrate that the frequency of wound infection and the frequency of…
- Trial name
- ISSAAC (NCT00572507)
- Testing
- MonoMax®
- Where
- 4 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Aesculap AG
Open Abdomen After Damage Control Laparotomy
Use of Hypertonic Saline After Damage Control Laparotomy to Improve Early Primary Fascial Closure
Damage control laparotomy (DCL) has proven to be a successful means to improve survival in severely injured patients.1-5 However, the consequences of not being able to close the fascia after the initial operation due to…
- Trial name
- NCT02297659
- Testing
- Primary Fascial Closure, wound vac dressing application
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- San Antonio Military Medical Center
Pain Score Reduction, Cesarian Section
Stratafix vs. PDS (Fascial Closure RCT)
This proposed prospective, randomized, single-blinded controlled trial will directly compare Stratafix anti-microbial barbed sutures and standard PDS sutures for fascial closure at the time of Cesarean delivery.
- Trial name
- NCT07574086
- Testing
- Polydioxanone Plus, Polydioxanone (PDS)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Ventral Incisional Hernia
Observational Study to Evaluate Ventral Incisional Hernia Repair Using a Biologic Mesh (Cook Biodesign)
The purpose of this study is to evaluate the efficacy of the Cook Biodesign mesh for the repair of complex ventral incisional hernias.
- Trial name
- NCT02129140
- Testing
- Hernia graft/mesh
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colon Cancer, Rectal Cancer
The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery
This clinical trial aims to evaluate the safety and feasibility of mid-line fascial suturing using MONOFIX sutures in patients undergoing minimally invasive surgery for colorectal cancer.
- Conditions
- Colon Cancer, Rectal Cancer, Colon Adenocarcinoma, Rectal Adenocarcinoma
- Trial name
- NCT05872334
- Testing
- Monofix
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Fascial Closure
A New Abdomen Closure Technology Based on Component Separation: a Prospective Randomized Controlled Trial
At present, open-type abdominal surgery is routine access into the abdomen. Median incision is the common choice with open-type abdominal surgery. Layered abdomen-closing is often used at the end-time of the surgery.
- Trial name
- NCT03111134
- Testing
- modified component separation technique
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Wound; Abdomen, Abdominal Wall
The Biomechanical Effects of Flaccid Paralysis Induced by Botulinum Toxin a After Damage Control Laparotomy
Damage control laparotomy (DCL) is a life saving maneuver used with success in trauma and acute general surgery patients. The technique involves source control of sepsis and hemorrhage with an abbreviated laparotomy.
- Trial name
- NCT01495962
- Testing
- Botulinum Toxin Type A
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Incisional Hernia of Anterior Abdominal Wall
Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.
- Trial name
- NCT04512469
- Testing
- Low molecular weight mesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's