Clinical trials: Fascial Closure
Post-operative Pain, Fascial Closure
Fascial Closure Techniques Post-Operative Pain Laparoscopy
This study compares post-operative incisional pain on post-operative days 1 and 7 who will undergo gynecologic laparoscopic operations.
- Trial name
- NCT03254056
- Testing
- Conventional technique, Berci technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Cesarean Section, Postoperative Pain
Effect of Guide-Suture-Assisted Modified Fascial Closure on Postoperative Pain and Early Mobilization After Cesarean Section
This randomized controlled trial evaluates whether a guide-suture-assisted modified fascial closure technique reduces postoperative pain and improves early functional recovery compared with classical continuous fascial closure in…
- Trial name
- GSMF-CS (NCT07436520)
- Testing
- Classical continuous fascial closure, Guide-suture-assisted modified fascial closure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Fascial Closure
A New Abdomen Closure Technology Based on Component Separation: a Prospective Randomized Controlled Trial
At present, open-type abdominal surgery is routine access into the abdomen. Median incision is the common choice with open-type abdominal surgery. Layered abdomen-closing is often used at the end-time of the surgery.
- Trial name
- NCT03111134
- Testing
- modified component separation technique
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Open Abdomen After Damage Control Laparotomy
Use of Hypertonic Saline After Damage Control Laparotomy to Improve Early Primary Fascial Closure
Damage control laparotomy (DCL) has proven to be a successful means to improve survival in severely injured patients.1-5 However, the consequences of not being able to close the fascia after the initial operation due to…
- Trial name
- NCT02297659
- Testing
- Primary Fascial Closure, wound vac dressing application
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- San Antonio Military Medical Center
Open Abdomen, Fascial Closure
Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction
The purpose of this multicenter trial is to prospectively evaluate a novel combination of vacuum assisted wound closure (VAWC) and mesh mediated fascial traction for closure of open abdomens.
- Trial name
- NCT00494793
- Testing
- VAWC and mesh mediated fascial traction
- Where
- 5 sites in Sweden
- Volunteers
- 111 people
- Sponsor
- Skane University Hospital
Damage Control, Trauma Abdomen
BIA Guided-fluid Management in Postinjury Open Abdomen
Fluid overload (FO), resulting from high volume fluid therapy, is frequent and contributes to excessive visceral edema, delayed fascial closure, and adverse outcomes among postinjury open abdomen (OA) patients.
- Conditions
- Damage Control, Trauma Abdomen, Acute Compartment Syndrome
- Trial name
- BGFM (NCT03466684)
- Testing
- BIA-guided fluid resuscitation protocol, Traditional fluid resuscitation protocol
- Volunteers
- 140 people
- Sponsor
- Nanjing PLA General Hospital
Parastomal Hernia
Fascial Defect Closure for Minimally Invasive Parastomal Hernia Repair
Fascial closure was not originally a routine component of minimally invasive parastomal hernia repairs, but several recent advancements have made fascial closure more common in this context.
- Trial name
- NCT05514600
- Testing
- closure of parastomal hernia fascial defect
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Gynecologic Disease
Effect of Barbed Suture Fascia Closure on Incisional Hernia in Midline Laparotomy for Gynecological Diseases (BARBHER)
Investigators will compare the incidence of incisional hernia in women who underwent midline laparotomy whose abdominal fascia was closed with barbed suture vs. conventional non-barbed suture.
- Trial name
- BARBHER (NCT04643197)
- Testing
- Barbed PDS suture (STRATAFIX Symmetric PDS Plus), Non-barbed PDS suture (PDS Plus)
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Wound Healing Disorder, Impaired Wound Healing
Treatment Study of Vacuum Assisted Closure for Postsurgical Subcutaneous Abdominal Wound Healing Impairments
This clinical study is performed in several German, Dutch and Belgian hospitals to evaluate the efficacy of Vacuum Assisted Closure® (V.A.C.®) for the treatment of postsurgical abdominal wound healing impairments after surgery.
- Conditions
- Wound Healing Disorder, Impaired Wound Healing, Abdominal Wound Healing Disorder, Abdominal Wound Healing Impairment
- Trial name
- SAWHI (NCT01528033)
- Testing
- Vacuum Assisted Closure®, Standard conventional wound therapy
- Where
- 15 sites in Belgium, Germany
- Volunteers
- 539 people
- Sponsor
- University of Witten/Herdecke
Ventral Incisional Hernia
Observational Study to Evaluate Ventral Incisional Hernia Repair Using a Biologic Mesh (Cook Biodesign)
The purpose of this study is to evaluate the efficacy of the Cook Biodesign mesh for the repair of complex ventral incisional hernias.
- Trial name
- NCT02129140
- Testing
- Hernia graft/mesh
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hernia, Ventral
Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial
This study is comparing the outcomes patients undergoing LVHR, PFC as opposed to a bridged repair with assessment of patient reported satisfaction and function at 6 months of follow-up.
- Trial name
- NCT02363790
- Testing
- LVHR PFC, Bridging LVHR
- Where
- 5 sites in United States
- Volunteers
- 189 people
- Sponsor
- The University of Texas Health Science Center, Houston
Open Abdomen, Temporary Abdominal Closure
Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated Fascial Traction in Patients With Open Abdomen
Open abdomen therapy is used in trauma and non-trauma patients where the abdomen is not possible to close, or the intraabdominal conditions is not suitable for closure.
- Conditions
- Open Abdomen, Temporary Abdominal Closure, Incisional Hernia
- Trial name
- VAWCPOM (NCT05568238)
- Testing
- Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated fascial traction (VAWCPOM)
- Volunteers
- 100 people
- Sponsor
- Skane University Hospital
Fascial Closure
Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy
The primary objective of this study is to identify the optimal method of fascial closure of a laparotomy incision in high risk patients for intra-abdominal complications.
- Trial name
- NCT02145052
- Testing
- Continuous suture, Interrupted suture
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Massachusetts General Hospital
Ventral Hernia
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
A ventral hernia happens when the muscles in the front of your belly become weak and let organs push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems.
- Trial name
- NCT07226791
- Testing
- AGN-151607-DP
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- AbbVie
Open Abdomen, Incisional Hernia
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen…
- Conditions
- Open Abdomen, Incisional Hernia, Definitive Fascial Closure, Emergency Abdominal Surgery
- Trial name
- SHIELD (NCT07835334)
- Testing
- Definitive Fascial Closure Without Prophylactic Mesh, Prophylactic Onlay Mesh Placement
- Volunteers
- 30 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Pilonidal Sinus
GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Surgical treatment is still gold standard for pilonidal sinus disease. Several surgical techniques have been proposed to treat this disease in the last two decades.
- Trial name
- GLUE (NCT03914729)
- Testing
- Primary Closure, Gluteus Maximus Fascia Plasty Flap
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Russian Society of Colorectal Surgeons
Surgical Site Infection
Effect of a Combination of Bundles on Surgical-site Infection After Elective Colorectal Surgery
A prospective randomized clinical trial will be performed. Patients will be randomized in 2 groups. The experimental group will undergo the combined application of intraperitoneal irrigation with clindamycin and gentamicin…
- Trial name
- NCT03081962
- Testing
- Bundle, Standard care
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital General Universitario Elche
Ventral Incisional Hernia
Shear-Wave Elastography
Prospective cohort study of patients with midline ventral incisional hernia with a range of hernia morphology who plan to undergo open retromuscular VHR.
- Trial name
- ELASTOGRAPHY (NCT06306976)
- Testing
- Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Open Abdomen, Temporary Abdominal Closure
Randomized Pilot Study Comparing Two Vacuum-wound-dressings for Open Abdomen Treatment
The primary purpose of the study is to determine whether two vacuum-wound-dressing techniques (the so called "abdominal dressing" versus "vacuum-pack-technique") are equally effective in the treatment of open abdomen.
- Trial name
- ABDOVAC (NCT00834314)
- Testing
- Vacuum-Pack-technique for temporary abdominal closure, Abdominal-dressing-technique for temporary abdominal closure
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Universitätsmedizin Mannheim
Pregnancy Related, Cesarean Section
Fascial Closure and Post-caesarean Pain
This study will evaluate post-operative pain in patients undergoing elective caesarean sections based on the method of fascial closure.
- Conditions
- Pregnancy Related, Cesarean Section, Post-operative Pain, Fascial Closure
- Trial name
- NCT04999670
- Testing
- Fascial closure method during caesarean section via pfannenstiel incision.
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre