Clinical trials: Fasting, Intermittent
Cognitive Function
Effect of Sprint Interval Training and Intermittent Fasting on Cognitive Function
Several lifestyle modifications, such as manipulating diet and exercise, have been shown to enhance cognitive function. This study aims to determine if a combination of Sprint Interval Training (SIT) and Time Restricted Eating…
- Trial name
- NCT05152719
- Testing
- Cognitive Performance
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
PreDiabetes
2-A-Day Study: Twice a Day Meals Study.
Caloric restriction increases lifespan and/or healthspan across multiple species. However implementation of long-term CR in humans is problematic and unacceptable to many individuals.
- Trial name
- NCT03809299
- Testing
- Ad libitum meal timing, Twice a day meals
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Obesity, Abdominal
The Impact Of An Intermittent Energy Restricted Diet On Insulin Sensitivity In Men and Women With Central Obesity
An intermittent energy restricted (IER) diet may modify cardio-metabolic disease risk factors compared to an energy-matched continuous energy restricted (CER) diet.
- Trial name
- Met-IER (NCT02679989)
- Testing
- Intermittent Energy Restriction, Continuous Energy Restriction
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Fasting, Healthy
Effects of a Time Restricted Eating Protocol on Resistance Training Men
The study sought to investigate the effects of 16/8 time restricted eating (TRE) with windows of 16 hours of fasting and 8 hours of eating on on body composition, muscle strength, and metabolic factors during resistance training…
- Trial name
- NCT04668378
- Testing
- Time restricted eating, Normal Diet
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Padova
Intermittent Claudication
Bioequivalency Study of 50 mg Cilostazol Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Cilostazol Tablets, 50 mg, to PLETAL® Tablets, 50 mg (OTSUKA Pharmaceuticals) under fasting conditions using a single-dose, randomized, 2-treatment…
- Trial name
- NCT00602407
- Testing
- Cilostazol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Metabolic Syndrome, Obesity and Obesity-related Medical Conditions
Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome
The goal of this intervention trial is to assess the effects of intermittent fasting, both alone and in combination with high-intensity interval training, on patients with obesity and metabolic syndrome.
- Trial name
- FIT (NCT06885255)
- Testing
- Alternate day fasting, Time restricted eating, High-intensity interval training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Fasting
Role of Leptin in the Neuroendocrine and Immune Response to Fasting
The purpose of this study will be to determine whether giving leptin (r-metHuLeptin) to a person when he or she is fasting will reverse changes in metabolism, and hormone levels, and immune function associated with fasting, which…
- Trial name
- NCT00140231
- Testing
- r-metHuLeptin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Energy Metabolism
Dynamic Effects of Different Dietary Interventions on Visceral Fat and Biochemical Markers
This randomized clinical trial aims to evaluate the dynamic effects of various dietary interventions on visceral fat and biochemical markers among healthy adults.
- Trial name
- NCT06754306
- Testing
- Balanced diet (100% energy), 16+8 time-restricted eating group (100% energy), 16+8 time-restricted eating group (75% energy)
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cancer Prevention
Family-Based Meal Timing for Cancer Prevention Among Native Hawaiian and Other Pacific Islanders: FAMTIME
Native Hawaiian or other Pacific Islanders (NHPI) including those from Polynesia, Micronesia, and Melanesia, are the fastest growing racial/ethnic group in the U.S., but they are vastly underrepresented in health research.
- Trial name
- FAMTIME (NCT07262593)
- Testing
- Time Restricted Eating (TRE), Medically Tailored Meals (MTM)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Inflammatory Markers
Time-Restricted Feeding
We propose to conduct a randomized 6-day isocaloric crossover feeding study in humans with prediabetes and obesity. We will study the effect of restricting the timing of caloric intake to earlier in the day (TRF) versus later in…
- Conditions
- Obesity, Inflammatory Markers, Glycemic Variation, Time Restricted Feeding
- Trial name
- TRIO (NCT04884659)
- Testing
- Time restricted feeding arm, usual feeding pattern arm
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Obesity, Fasting
The Effect of Intermittent Energy Restriction Using Meal Replacements in Overweight Chinese Subjects
Background and Aims: The "5:2 diet", a form of intermittent energy restriction, has been popularized in Europe and USA. The rationale behind this approach is that two days of dieting is potentially more achievable, yet long…
- Trial name
- NCT02606669
- Testing
- Meal Replacement
- Where
- Singapore
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Khoo Teck Puat Hospital
Type 2 Diabetes, Insulin Resistance
Intermittent Fasting for Metabolic Health, Does Meal Timing Matter?
Obesity is a serious medical condition, the adverse consequences of which include increased risk of cardiovascular disease, diabetes mellitus, reduced fertility and cancer.
- Trial name
- NCT02633722
- Testing
- Lifestyle intervention B, Lifestyle Intervention D
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Time-restricted Eating, Diet Quality
What Or When to Eat to Reduce the Risk of Type 2 Diabetes (WOW)
A parallel, single-blinded, multi-centre randomized controlled trial conducted at the South Australian Health and Medical Research Institute (SAHMRI) and the Mary Mackillop Institute for Health Research (MMIHR; Australian…
- Trial name
- NCT04762251
- Testing
- Time-restricted eating, Current Best Practice
- Where
- 2 sites in Australia
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Neoplasms, Leukemia, Lymphocytic, Chronic
Intermittent Fasting and CLL/SLL
What are the investigators trying to do? By most measures, humans consume more food than needed. Over several decades, overconsumption has led to an increase in a number of diseases, including cancer.
- Conditions
- Neoplasms, Leukemia, Lymphocytic, Chronic, Lymphoma, Small Lymphocytic, Intermittent Fasting
- Trial name
- NCT04626843
- Testing
- Intermittent fast
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eleah Stringer
Obesity
Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial)
Calorie restriction (CR) is the most important treatment for weighting loss. In recent years, two novel types of intermittent fasting recently have gained more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST-3 (NCT06302803)
- Testing
- Intermittent fasting plus time-restricted eating, Calorie restriction
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Healthy
Intermittent Fasting on the Blood Microbiome
The investigators previously demonstrated that the gut microbiome can be remodeled by one month of intermittent fasting (OMIF) in healthy volunteers and animal models, with a notable alteration observed in its overall composition…
- Trial name
- NCT06678516
- Testing
- Intermittent fasting
- Where
- 2 sites in China, Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Intermittent Fasting, Healthy
Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study
There is a growing interest in personalized health strategies, including diet, exercise, and fasting regimens, to enhance metabolic fitness.
- Conditions
- Intermittent Fasting, Healthy, Digital Health
- Trial name
- NCT06630637
- Testing
- Glucose-Ketone Index (GKI) monitoring, Continuous Glucose Monitoring (CGM), Digital dynamometer
- Where
- Singapore
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institute for Digital Medicine (WisDM)
Sleep, Appetitive Behavior
Time-restricted Eating, Appetite and Sleep
The goal of this clinical trial is to learn about the effect of time-restricted eating (TRE) to 10 hours per day on the regulation of appetite, the desire to eat, and the quality and duration of nocturnal sleep in adults with…
- Trial name
- SLEEPFAST (NCT06485037)
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chile
Mental Health, Perimenopause
Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women
This study will explore how intermittent fasting (specifically the 16/8 method) affects the mental health of women who are in the perimenopause stage.
- Conditions
- Mental Health, Perimenopause, Intermittent Fasting
- Trial name
- NCT07481513
- Testing
- Intermittent fasting (16/8)
- Where
- Lebanon
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Obesity
Classic vs. High-Fat Intermittent Fasting Effects
Poor eating habits contribute to weight gain and obesity, leading to numerous metabolic issues such as diabetes and cardiovascular diseases.
- Trial name
- NCT06515639
- Testing
- Diet therapy for Classic IF diet group, Diet therapy for low carb-High fat IF diet group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University