Clinical trials: Fasting
Fasting
Role of Leptin in the Neuroendocrine and Immune Response to Fasting
The purpose of this study will be to determine whether giving leptin (r-metHuLeptin) to a person when he or she is fasting will reverse changes in metabolism, and hormone levels, and immune function associated with fasting, which…
- Trial name
- NCT00140231
- Testing
- r-metHuLeptin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy
Bioequivalency Study of Ranitidine Tablets 300 mg of Dr. Reddy's Under Fasting Conditions
The purpose of this study is to compare the rate and extent of absorption of ranitidine 300 mg tablets versus Zantac 300 mg tablets administered as 1 x 300 mg tablet under fasting conditions.
- Trial name
- NCT01131702
- Testing
- Ranitidine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Dyslipidemia
Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period
The purpose of this study was to assess the effect of eggplant extract capsules on the lipid profile of healthy individuals after an oral lipid overload test in a randomized, double-blind, placebo-controlled clinical trial.
- Trial name
- NCT00845637
- Testing
- Eggplant extract
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy Volunteers
Bioequivalence Study With Pharmacokinetic Endpoints, Comparing a Single Dose of Iron Sucrose Azad Injection of Azad Pharma Corporation (AG), With a Single Dose of Venofer® Injection of Vifor Corporation (AG) in Healthy Adult Volunteers
A Clinical Trial to Demonstrate the Comparability of the Two Iron Sucrose Injection Solutions Iron Sucrose Azad of Azad Pharma AG and Venofer® of Vifor Pharma AG.
- Trial name
- NCT02391181
- Testing
- Iron Sucrose Azad, Venofer®
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Azad Pharma AG
Chronic Obstructive Pulmonary Disease
A Trial to Assess the Bioequivalence of Generic Tiotropium Bromide Inhalation Powder and Reference Product in Healthy Adult Participants Under Fasting Conditions (Pilot)
Primary Objective: To evaluate the pharmacokinetics of Tiotropium Bromide Inhalation Powder (Strength:18 mcg; manufactured by Chia Tai Tianqing Pharmaceutical Group Co.
- Trial name
- NCT06326671
- Testing
- Tiotropium Bromide Inhalation Powder, Spiriva HandiHaler
- Where
- China
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Diabetes
Expanded PK and PD of Insulin Glulisine Versus Insulin Aspart in Healthy Volunteers
The purpose of this study was to compare the pharmacodynamics (course of the blood glucose-lowering effect and duration of effect) and pharmacokinetics (course of the concentration of study medication in the blood) of a single…
- Trial name
- NCT00969592
- Testing
- insulin glulisine, insulin aspart, insulin aspart, insulin glulisine
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Insulin Sensitivity, Obesity
The Metabolic Effects of Cynara Supplementation in Overweight and Obese Class I Subjects With Newly Detected Impaired Fasting Glycaemia.
Impaired fasting glucose (IFG) is a condition that precedes diabetes and increases the risk of developing it. Studies support the hypoglycemic effect of Cynara cardunculus (Cs) extracts due to the content of chlorogenic acid…
- Conditions
- Insulin Sensitivity, Obesity, Overweight
- Trial name
- NCT04616404
- Testing
- 500 mg of artichoke extract
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Hip Osteoarthritis, Hip Pain Chronic
Fast Track Total Hip Arthroplasty vs Standard Care
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT04211987)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Healthy
To Evaluate the Safety and PK Characteristics in Healthy Volunteers
The objective is to evaluate the safety and pharmacokinetic characteristics after co-administration of JW0101 and C2101 and administration of JW0102 in healthy volunteers under fasting conditions
- Trial name
- NCT06355349
- Testing
- Reference Drug or Test Drug
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Healthy
Food Reward Processing in the Human Brain
The aim of this study is to investigate the influence of different metabolic states and hormonal satiety signalling on responses in neural reward networks.
- Trial name
- NCT03081585
- Testing
- Satiety State
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Heidelberg Medical Center
Healthy
Fasting Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mg
The objective of this study was to investigate the bioequivalence of Mylan's divalproex sodium 500 mg extended-release tablets to Abbott's Depakote ER® 500 mg tablets following a single, oral 500 mg (1 x 500 mg) dose administered…
- Trial name
- NCT00647712
- Testing
- Divalproex Sodium Extended-Release Tablets 500 mg, Depakote ER® Tablets 500 mg
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Healthy
Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg
The objective of this study was to investigate the bioequivalence of Mylan's metformin hydrochloride ER tablets to Bristol-Myers Squibb's Glucophage® XR tablets following a single, oral 500 mg (1 x 500 mg) dose administered under…
- Trial name
- NCT00650234
- Testing
- Metformin Hydrochloride ER Tablets 500 mg, Glucophage® XR Tablets 500 mg
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Diet, Autophagy
Fasting Mimicking Diet and Autophagy
This study aims to evaluates autophagy in circulating white blood cells from generally healthy human volunteers exposed to fasting mimicking diet (FMD), a 5-day dietary regimen.
- Trial name
- NCT06115551
- Testing
- Fasting Mimicking Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- L-Nutra Inc
Bioequivalence
Bioequivalence Study of Clavamox, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (Pharmtechnology LLC, Belarus), and Augmentin®, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions
This is an open-label, randomized, single-center, single-dose, two-treatment, two-sequence, two-period, crossover, comparative study, where each subject will be randomly assigned to the reference or the test formulation in each…
- Trial name
- NCT03616301
- Testing
- Clavamox, Augmentin®
- Where
- Russia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Pharmacokinetics
Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers
The primary objective was to compare the rate and extent of absorption of Metformin XR after administration of a Test Product Metformin 1000 mg Prolonged Release Tablets (JSC Farmak, Ukraine) and Reference Product Glucophage® XR…
- Trial name
- NCT05123781
- Testing
- Metformin 1000 mg Prolonged Release Tablets (JSC Farmak, Ukraine), Glucophage® XR 1000 mg Prolonged Release Tablets (Merck Serono Ltd, UK)
- Where
- Czechia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
Obesity Prevention
Acute Time-Restricted Eating in Young Healthy Males
This study compared the metabolic response to three different eating windows (morning fast,12pm-8pm; evening fast, 8am-4pm; control, 8am-8pm).
- Trial name
- NCT05309798
- Testing
- Evening Fasting, Morning Fasting, Control
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Psoriasis and Psoriatic Arthritis
Bioequivalence Study of Two Products of Apremilast 30 mg Tablets in Healthy, Adult, Human Subjects
An open label, balanced, randomized, two-sequence, two-treatment, two-period, single oral dose, crossover, bioequivalence study in normal, healthy, adult, human subjects under fasting condition
- Trial name
- NCT06084663
- Testing
- Apremilast 30 mg Tablets, Otezla 30 mg film-coated tablets
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
EFFECT OF ADV7103 ON GASTRIC PH, Distal Renal Tublular Acidosis
A Phase 1 Study, to Evaluate the Effect of ADV7103 on Gastric pH Under Fed and Fasting Conditions in Adult Healthy Participants.
This was a Phase 1, single-center, randomized, controlled, Latin-square, open-label study to evaluate the effect of ADV7103 on the gastric pH, after administering a single oral dose of ADV7103 in healthy adult participants under…
- Trial name
- B06 (NCT07446881)
- Testing
- ADV7103
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Advicenne Pharma
Effect of Food
The Food Effect on Pharmacokinetics Study of QLC1101 in Healthy Subjects
This randomized, open-label, three-period, three-treatment crossover Phase I clinical trial is designed to evaluate the pharmacokinetic profile of QLC1101 capsules administered as a single oral dose under fasting conditions…
- Trial name
- NCT06980909
- Testing
- QLC1101
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Healthy
Bioequivalence Study of Rivastigmine 1.5 mg Capsules Under Fasting Conditions
This is a bioequivalence study of Rivastigmine 1.5 mg capsules and Exelon Administered as 1.5 mg capsule in Healthy subjects under fasting conditions.
- Trial name
- NCT01146067
- Testing
- Rivastigmine
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
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