Clinical trials: Fasting
Pancreatic Cancer
Comparison of Transmesocolic Versus Retromesenteric Reconstruction in Cephalic Duodenopancreatectomy (FAST Trial)
Objective: To compare the incidence of delayed gastric emptying (ISGPS 2007 criteria) between patients undergoing retromesenteric versus transmesocolic reconstruction after pancreaticoduodenectomy.
- Trial name
- FAST (NCT07368218)
- Testing
- Retromesenteric reconstruction, Transmesocolic reconstruction
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Hospital Universitari de Bellvitge
Healthy
Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fasting Conditions
The objective of this study was to compare the rate and extent of absorption of Purepac, a subsidiary of Alpharma Inc., U.S.A., galantamine and Janssen Pharmaceutica Products, L.P., U.S.A.
- Trial name
- NCT01190748
- Testing
- Galantamine 4 mg Tablet, single dose, Reminyl 4 mg Tablet, single dose
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Bioavailability Study
Relative Bioavailability of Early Phase and Late Phase Hetrombopag Olamine Formulations
The primary objective of the study is to evaluate the relative bioavailability of early phase and late phase hetrombopag olamine formulations in healthy Chinese adult subjects under fasting conditions.
- Trial name
- NCT04688008
- Testing
- Hetrombopag
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Infectious Diseases
Evaluate Bioequivalence of Burotam (1/1 g/Vial)
A randomized, single-dose, two-way crossover study to evaluate bioequivalence of two formulations of cefoperazone sodium and sulbactam sodium combination (1/1 g/vial) after intravenous infusion of 1 g cefoperazone sodium and 1 g…
- Trial name
- NCT05654090
- Testing
- cefoperazone sodium and sulbactam sodium
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Healthy
Bioavailability Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fasting Conditions.
The purpose of this study is to compare the single-dose relative bioavailability study of Levetiracetam Tablets 750 mg with Keppra® 750 mg Tablets under Fasting conditions.
- Trial name
- NCT01131897
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Hypertension
Crossover Bioequivalence Study of Irbesartan 300 mg Tablets Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Roxane Laboratories' Irbesartan 300 mg Tablets under fasted conditions
- Trial name
- NCT01712113
- Testing
- Irbesartan, Avapro
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Antithrombic Drug
Bioequivalence Study of Two Products of Apixaban 5mg Tablets in Healthy, Adult, Human Subjects
To compare the bioavailability and characterize the pharmacokinetic profile of the sponsor's test product relative to that of reference product after single oral dose administration in normal, healthy, adult, human subjects under…
- Trial name
- NCT06043297
- Testing
- Apixaban 5MG, Eliquis 5 mg
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Liver Cancer, Adult, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Time-restricted Eating and Healthy Eating in Patients With Metabolic Liver Disease or Cancer
This is a feasibility study that will collect data to assess the potential effect of nutritional intervention. This prospective single-site trial will enroll adult patients with liver diseases such as metabolic-dysfunction…
- Conditions
- Liver Cancer, Adult, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Obesity and Overweight
- Trial name
- TRE+HE (NCT06824974)
- Testing
- Time-restricted eating plus healthy diet
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Type 2 Diabetes
Food-Effect Bioavailability Study of FDC(Gemigliptin/Metformin HCl Sustained Release) 50/1000mg(25/500mg x 2tablets)
This study is designed to investigate the food-effects on FDC(gemigliptin/metformin HCl sustained release) 50/1000mg(25/500mg x 2tablets)
- Trial name
- NCT01747083
- Testing
- FDC(gemigliptin/metformin HCl sustained release 50/1000mg(25/500mg x 2tablets))
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Migraine Headache
Acute Stress Response in Migraine Sufferers
This study will examine the influence of stress and fasting on headache activity. Participants will receive both a control and stress session and be randomized to either fasting or not fasting for the visits.
- Trial name
- NCT03099070
- Testing
- Stress, Fasting
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Healthy Adult
Bioequivalence Study of Ferric Carboxymaltose Injection in Healthy Chinese Participants Under Fasting Conditions
The goal of this clinical trial is to compare the pharmacokinetic profile of the developed drug product and reference product in healthy participants under fasting condition.
- Trial name
- NCT07606105
- Testing
- Ferric Carboxymaltose Injection, Ferric Carboxymaltose Injection [Injectafer®]
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sichuan Huiyu Pharmaceutical Co., Ltd
Healthy Volunteers
Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1622, DWC202313, and DWC202314 in Healthy Volunteers Under Fasting Conditions
This study aims to evaluate the safety and pharmacokinetic characteristics of DWJ1622, DWC202313, and DWC202314 in healthy adult volunteers under fasting conditions.
- Trial name
- NCT07260851
- Testing
- DWJ1622, DWC202313, DWC202314
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy Adult Subjects
Bioequivalence of TTYP01 Tablets in Healthy Adult Subjects
This is a Phase 1, Randomized, Open-Label, Three-Treatment, Three-Period Crossover Study to Assess Bioequivalence and Safety of TTYP01 Tablets to Radicava® Injection, and Radicava ORS® in Healthy Adult Subjects Under Fasting…
- Trial name
- NCT06107205
- Testing
- TTYP01, Radicava, Radicava ORS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Shanghai Auzone Biological Technology Co., Ltd.
Healthy, Healthy Donors
Bioequivalence Study of Revolade® Eltrombopag 50 mg
Bioequivalence Study
- Trial name
- Eltrombopag (NCT06834451)
- Testing
- Revolade®, Eltrombopag (EPAG)
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centro de Atencion e Investigacion Medica
Extensively Decayed Primary Molars
Efficacy of Totalfill® and ProRoot MTA® as Pulpotomy Agent in Primary Molars
An experimental prospective double-blind, randomized clinical trial (RCT) with parallel design. To evaluate the outcome of using 2 pulpotomy agents: Totalfill® as study group and mineral trioxide aggregate (MTA®) as a control.
- Trial name
- NCT05149651
- Testing
- Totalfill, MTA
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy
A Relative Bioavailability Study of Bupropion XL 150 mg Tablets Under Fasting Conditions
To compare the rate and extent of absorption of Abrika Bupropion 150 mg XL Tablet to that of Wellbutrin XL® 150 mg Tablet after a single, one-tablet dose in fasted subjects.
- Trial name
- NCT00863941
- Testing
- Abrika Bupropion 150 mg XL Tablet, single dose, Wellbutrin XL® 150 mg Tablet, single dose
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Healthy
Fasting Study of Olanzapine Tablets 5 mg and Zyprexa® Tablets 5 mg
The objective of this study was to investigate the bioequivalence of Mylan's olanzapine 5 mg tablets to Eli Lilly's Zyprexa® 5 mg tablets following a single, oral 5 mg (1 x 5 mg) dose administered under fasting conditions.
- Trial name
- NCT00648921
- Testing
- Olanzapine Tablets 5 mg, Zyprexa® Tablets 5 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Congenital Heart Diseases, Cardiac Diseases
An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function
This project aims to evaluate a new cardiac MRI technique called the Free-Running Framework (FRF), which could simplify and accelerate the process of acquiring cardiac images.
- Trial name
- FAST-CMR (NCT07613398)
- Where
- 20 sites in United States, Australia and 8 more
- Volunteers
- 300 people
- Sponsor
- Matthias Stuber
Short Term Treatment of Insomnia
Bioequivalency Study of Zaleplon 10 mg Capsules Under Fasting Conditions
The objective of this study was to show the bioequivalence of a Roxane Laboratories' Zaleplon Capsules, 10 mg, to Sonata ® Capsules, 10 mg (Jones Pharma) under fasting conditions using a single-dose, randomized, 2-treatment…
- Trial name
- NCT00694187
- Testing
- Zaleplon
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Bioequivalence Study in Healthy Subjects
Bioequivalence Assessment Between Two Imeglimin Hydrochloride Film Coated Tablet Formulations
An open label, randomized, single-dose, two-sequence, two-period, crossover study to assess the bioequivalence of Imeglimin HCl in Glimcoza 500 mg film coated tablet (Test product) in comparison with Twymeeg® 500 mg tablet…
- Trial name
- BEGliTabATCO (NCT07127094)
- Testing
- Test Product (Glimcoza), Reference (R) Twymeeg®
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Aya Mohammed Abdel Magid Abdel Hamid