Clinical trials: Fasting Mimicking Diet
Cancer, Ovarian, Chemotherapy Effect
Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies
This study evaluates how lifestyle modifications that may be made to manage chemotherapy side effects in patients with gynecologic malignancies.
- Conditions
- Cancer, Ovarian, Chemotherapy Effect, Calorie Deficiency, Fasting, Intermittent
- Trial name
- NCT06376604
- Testing
- Fasting Mimicking Diet, Chemotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- L-Nutra Inc
Malignant Neoplasm, Cancer
Safety, Feasibility and Metabolic Effects of the Fasting Mimicking Diet (FMD) in Cancer Patients
In preclinical studies, cyclic calorie-restricted diets reduce the risk of several cancers and improve the antitumor activity of standard treatments against already established malignancies.In particular, the fasting mimicking…
- Trial name
- NCT03340935
- Testing
- Fasting mimicking diet
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Filippo de Braud
Depression
The Evaluation of the Efficacy of a Fasting Mimicking Diet Added to Functional Therapy for Depression
Depression has to be considered as a systematic illness involving the whole body, it is often associated with low-grade inflammation and alterations of the microbiome.
- Trial name
- NCT04050475
- Testing
- Fasting Mimicking Diet
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Triple-negative Breast Cancer
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer
Glucose starvation and metformin have synergistic antitumor effects that are mediated through the concomitant inhibition of glycolysis and mitochondrial oxidative phosphorylation.
- Trial name
- BREAKFAST (NCT04248998)
- Testing
- Fasting-mimicking diet, Metformin, Preoperative chemotherapy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Fat Mass, Risk Factors Cardiovascular Disease
Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging
A large ongoing randomized, open-label trial aimed at evaluating the effects of two different dietary interventions, FMD and LD, on body composition and cardiovascular (CV) biomarkers in a real word population (NCT05698654) is…
- Conditions
- Fat Mass, Risk Factors Cardiovascular Disease, Epigenetic Aging, Metabolism Changes
- Trial name
- NCT07255300
- Testing
- fasting mimicking diet
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Prostate Adenocarcinoma
Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
This is a Phase 2, randomized two-armed, multi-site study of 138 patients with metastatic castrate sensitive prostate adenocarcinoma. Patients will be randomized 1:1 to receive the fasting mimicking diet, or usual diet.
- Trial name
- NCT05832086
- Testing
- Fasting Mimicking Diet (FMD), Standard Anti-Cancer Diet
- Where
- 3 sites in United States
- Volunteers
- 138 people
- Sponsor
- Stephen Freedland
Multiple Sclerosis
A run-in Study on the Safety and Tolerability of a Fasting Mimicking Diet in Relapsing Remitting Multiple Sclerosis
This study is an open-label, single-arm, run-in study in patients with RRMS treated with first line therapies (interferon-beta, glatiramer acetate, teriflunomide and dimethyl fumarate), assessing the feasibility and tolerability…
- Trial name
- FAST-MS (NCT06039007)
- Testing
- 7-day Fasting-Mimicking Diet (7-DAY FMD)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Ospedale Policlinico San Martino
Fasting Mimicking Diet, Leukemia
Fasting Mimicking Diet With Chemotherapy in Patients With Leukemia
The goal of this clinical trial is to investigate The effect of fasting mimicking diet with chemotherapy on the number of blasts and platelets and quality of life in patients with acute lymphoid leukemia and acute myeloid…
- Trial name
- NCT06353698
- Testing
- fasting mimicking diet
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- National Nutrition and Food Technology Institute
Periodontal Disease, AVDC Stage 3, Periodontal Disease, AVDC Stage 4
Fasting-mimicking Diet and Periodontitis (FMD)
Periodontitis (gum disease) leads to the formation of gum pockets. Its treatment involves deep cleaning of the teeth, to remove soft and hard tooth deposits under the gum line.
- Conditions
- Periodontal Disease, AVDC Stage 3, Periodontal Disease, AVDC Stage 4, Periodontitis
- Trial name
- FMD (NCT06074861)
- Testing
- Fasting-mimicking diet + non-surgical periodontal therapy
- Where
- 5 sites in Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Internacional de Catalunya
Diabetes Mellitus, Type 2
Clinical Feasibility and Efficacy of Intermittent Use of a Fasting Mimicking Diet in the Treatment of Type 2 Diabetes
In this randomized, controlled, assessor blinded and prospective intervention study the investigators will evaluate the clinical feasibility and effectiveness of intermittent use of a fasting mimicking diet in patients with type…
- Trial name
- NCT03811587
- Testing
- Fasting Mimicking diet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Leiden University Medical Center
Healthy Subjects, Cancer
The Effect of a Fasting MimickINg Diet on the Immune System
Fasting or a Fasting Mimicking diet (FMD) can lower blood concentration of glucose and IGF1. Since cancer cells rely mostly on a glucose-based metabolism, FMD renders cancer cells more vulnerable to chemotherapy, thereby…
- Conditions
- Healthy Subjects, Cancer, Neoplasms
- Trial name
- FIND (NCT04833439)
- Testing
- Fasting Mimicking Diet
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Epithelial Ovarian Cancer
Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer
The goal of this clinical trial is to see if timed fasting (periods of time that you don't eat) in participants who are receiving chemotherapy prior to surgery is achievable, safe and can improve quality of life, symptoms and…
- Trial name
- NCT06386887
- Testing
- Intermittent Fasting, Neoadjuvant chemotherapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Inflammatory Bowel Disease, Diet Modification
The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC).
- Conditions
- Inflammatory Bowel Disease, Diet Modification, Ulcerative Colitis
- Trial name
- NCT03615690
- Testing
- Fasting Mimicking Diet, Regular Diet
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Triple Negative Breast Cancer (TNBC), Early Setting
LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer
LESLIE is a multicentric randomized controlled trial in patients with triple negative breast cancer receiving neoadjuvant chemo/immunotherapy (NAT).
- Trial name
- LESLIE (NCT06831955)
- Testing
- Exercise Therapy, Fasting-Mimicking Diet, SOC
- Where
- 10 sites in Belgium
- Volunteers
- 356 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Multiple Sclerosis
Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)
In the proposed study, investigators will assess the safety and feasibility of cycles of a fasting mimicking diet (FMD) and its effect on Multiple Sclerosis Quality of Life (MSQOL) in relapsing MS (RMS) patients treated with…
- Trial name
- FMDMS (NCT06515782)
- Testing
- Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Carcinoma, Renal Cell, Metastatic Renal Cell Carcinoma
Fasting-Mimicking Diet Combined With IO-TKI Combination Therapy in Patients With Metastatic Renal Cell Carcinoma
This study is testing whether adding a 5-day fasting-mimicking diet (FMD) can help people with advanced kidney cancer when given together with standard first-line cancer medicines.
- Conditions
- Carcinoma, Renal Cell, Metastatic Renal Cell Carcinoma, Advanced Renal Cell Carcinoma
- Trial name
- NCT07500831
- Testing
- Fasting mimicking diet, Toripalimab, Axitinib
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Qilu Hospital of Shandong University