Clinical trials: Fasting Period
Healthy
Bioequivalence Study of Eldecalcitol Soft Capsule in Healthy Chinese Subjects
A single-center, open-label, randomized, two-period, crossover study design of pharmacokinetics and bioavailability in healthy Chinese subjects under fasting conditions.
- Trial name
- NCT05406050
- Testing
- reference eldecalcitol soft capsule, test eldecalcitol soft capsule
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Healthy
Comparative Pharmacokinetic, Pharmacodynamic, and Safety Study of 1 Dose of Aspirin for Injection and Oral Aspirin Tablets in Healthy Adult Subjects
The purpose of this study is to compare the safety, pharmacokinetics, and pharmacodynamic effects of aspirin administered intravenously with aspirin administered orally.
- Trial name
- NCT07323680
- Testing
- 325 mg Oral Aspirin, 325 mg aspirin by rapid IV push
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rhoshan Pharmaceuticals Inc
Bioequivalence
Bioequivalence Study of Two Formulations of Tablets Aceclofenac 100 mg in Healthy Volunteers Under Fasting Conditions
This is an open-label, randomized, two period, single-center, crossover, comparative study, where each participant will be randomly assigned to the reference (Airtal ®, 100 mg film-coated tablets) or the test (Aceclofenac, 100 mg…
- Trial name
- NCT05339373
- Testing
- Aceclofenac film-coated tablet 100 mg, Airtal® film-coated tablet 100 mg
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Dyslipidemia
Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period
The purpose of this study was to assess the effect of eggplant extract capsules on the lipid profile of healthy individuals after an oral lipid overload test in a randomized, double-blind, placebo-controlled clinical trial.
- Trial name
- NCT00845637
- Testing
- Eggplant extract
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Prostatic Hyperplasia
A Study To Compare Giving AVODART And FLOMAX Together Or In A Combination Capsule In The Fed And Fasted State
This study will be an open-label, randomized, single dose, three way partial crossover study in healthy male subjects. The aim of the study is to evaluate bioequivalence of a fixed dose combination (FDC) capsule of dutasteride…
- Trial name
- NCT00537654
- Testing
- Treatment sequence A, Treatment sequence B, Treatment sequence C
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Anthelmintic Agent
Bioequivalence Study to Compare Two Tablets of Ivermectin Tablets (3 mg Ivermectin) Versus Two Tablets of Stromectol ® Tablets (3 mg Ivermectin), in Healthy Subjects Under Fasting Conditions
Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare two tablets of Ivermectin tablets (3 mg Ivermectin) versus two tablets of Stromectol ® tablets (3 mg Ivermectin), in…
- Trial name
- NCT05082753
- Testing
- Ivermectin tablets (3 mg Ivermectin), Stromectol ® tablets
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Bipolar Disorder
Bioequivalency Study of 300 mg Lithium Carbonate Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane lithium carbonate 300 mg extended release tablet formulation compared to Solvay's Lithobid 300 mg extended release tablet under fasting conditions using a…
- Trial name
- NCT00601536
- Testing
- Lithium
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Fasting State
Bioequivalence Study of Carvedilol Tablets USP 12.5 mg Under Fasting Condition
This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, cross over pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01577914
- Testing
- Carvedilol Tablets USP 12.5 mg, Carvedilol
- Where
- India
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Dyslipidemia, Hypertension
A Study to Evaluate the Safety and Pharmacokinetics of AD-231 Compared to Coadministration of AD-231A, AD-231D and AD-231C
A Study to Evaluate the Safety and Pharmacokinetics of AD-231 Compared to Coadministration of AD-231A, AD-231D and AD-231C
- Trial name
- NCT07590167
- Testing
- AD-231, AD-231A, AD-231D and AD-231C
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Cardiovascular Disease
Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-333 Low Dose in Healthy Volunteers
This study is a randomized, open-label, single dose, 3-period partial replicated crossover study to evaluate the pharmacokinetic profiles and safety of CKD-333 low dose in healthy volunteers under fasting conditions.
- Trial name
- NCT04611932
- Testing
- CKD-330 Tab. and D090 Tab., CKD-333 Tab.
- Where
- South Korea
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy
Bioequivalence Study of Pantoprazole Sodium 40 mg Delayed Release Tablets Fasting Study
This study was to compare the single-dose oral bioequivalence of Pantoprazole sodium 40 mg delayed release tablets (containing 45.1 mg of Pantoprazole sodium sesquihydrate equivalent to 40 mg of Pantoprazole) of OHM Laboratories…
- Trial name
- NCT01654705
- Testing
- Pantoprazole
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Bioequivalence
Bioequivalence Study of Clavamox, Film-coated Tablets, 875 mg + 125 mg Pharmtechnology LLC, Belarus), and Augmentin®, Film-coated Tablets, 875 mg + 125 mg (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions
This was an open-label, randomized, single-center, single-dose, two-treatment, two-sequence, two-period, crossover, comparative study, where each subject was randomly assigned to the reference or the test formulation in each…
- Trial name
- NCT03702894
- Testing
- Clavamox, Augmentin®
- Where
- Russia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Healthy
Pharmacokinetics of SP-104
This open-label, 3-period, 3-treatment, randomized study will characterize the pharmacokinetics and safety and tolerability of SP-104 under fasting and fed conditions as compared to the pharmacokinetics of Naltrexone…
- Trial name
- NCT05002946
- Testing
- SP-104, Naltrexone Hydrochloride 50Mg Oral Tablet
- Where
- New Zealand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Epilepsy
An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.
An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.
- Trial name
- NCT05788159
- Testing
- Lacosamide Tablets, Lacosamide extended release tablets
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
Healthy
Bioequivalence Study of Zafirlukast Tablets 20 mg of Dr. Reddy's Laboratories Limited Under Fasting Condition
The objective of this study was to compare the relative bioavailability of zafirlukast tablets 20 mg with that of 'ACCOLATE®' tablets 20 mg (zafirlukast tablets 20 mg) in healthy, adult, human, subjects under fasting conditions…
- Trial name
- NCT01283061
- Testing
- Zafirlukast
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Depression
Bioequivalency Study of Sertraline Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Sertraline Tablets, 100 mg, to Zoloft® Tablets, 100 mg (Pfizer) under fasting conditions using a single-dose, 2-treatment, 2-period, crossover design.
- Trial name
- NCT00602849
- Testing
- Sertraline
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Healthy
Bioequivalence Study of Clarithromycin 250 mg/5 mL Powder for Oral Suspension Under Fasting Conditions
To compare the single-dose oral bioavailability of clarithromycin 250-mg/5 mL powder for oral suspension of Ranbaxy Laboratories with that of Abbott Laboratories (Biaxin®) following administration of a 250 mg/5 mL dose in…
- Trial name
- NCT00775255
- Testing
- clarithromycin 250 mg/5 mL powder for oral suspension
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Gastritis
A Clinical Trial to Assess the Pharmacokinetics and Safety of AD-229 Compared to AD-2291 in Healthy Adults
The study compare and evaluate the safety and pharmacokinetic characteristics between the administration of AD-229 and the administration of AD-2291 in healthy adults.
- Trial name
- NCT07385248
- Testing
- AD-229, AD-2291
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Bacterial Infections
Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate.
The purpose of this study is to determine whether Terix Labs Ltd Metronidazole benzoate (400 mg Metronidazole Per Sachet Oral Granules) is bioequivalent to 500 mg Sanofi-aventis Flagyl 125 mg/5 ml (125 mg Metronidazole Per 5 ml…
- Trial name
- NCT02146209
- Testing
- Metronidazole benzoate, Flagyl 125 mg/5 ml oral suspension, Flagyl 400 mg Tablets
- Where
- Jordan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Verisfield UK Ltd. Greek Branch
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.