Clinical trials: Fasting Plasma Glucose
Type 2 Diabetes, Glucose Tolerance Impaired
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
With REMD's glucagon receptor antagonist, the study team propose to provide a comprehensive examination of the effect of elevated plasma glucagon concentrations in Type 2 Diabetes Mellitus (T2D) patients on: (i) glucose…
- Conditions
- Type 2 Diabetes, Glucose Tolerance Impaired, Insulin Sensitivity
- Trial name
- NCT05093517
- Testing
- REMD-477
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hyperlipidemia, Impaired Fasting Glycemia
Effects of Hypolipemic Treatment on Adipokines
The study is planned to show whether monotherapies or combined hypolipemic therapy influence the fasting plasma glucose, serum adipokines (leptin, adiponectin, resistin) and proinflammatory cytokines (interleukin-6, TNF alpha)…
- Trial name
- NCT01099176
- Testing
- To compare monotherapies and combined therapy with each other
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Cardiovascular Diseases, Lipid Disorder
SRMA of the Effect of Soy Milk vs Cow's Milk on Cardiometabolic Outcomes
Dairy consumption has shown associations with decreased incidence of cardiometabolic diseases. With the growing interest in plant-based eating, and the mounting evidence for the cardiovascular benefits of plant forward diets…
- Conditions
- Cardiovascular Diseases, Lipid Disorder, Metabolic Disease, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT05637866
- Testing
- Soy milk
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes Mellitus (GDM), Oxidative Stress
Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational Diabetes
Our study aims to explore the influence of dietary chromium supplementation in the form of chromium picolinate, at different doses (200 µg and 400 µg per day), on the health of pregnant women with gestational diabetes.
- Conditions
- Gestational Diabetes Mellitus (GDM), Oxidative Stress, Inflammatory Status, Insulin Resistance
- Trial name
- Cr and GDM (NCT06860087)
- Testing
- Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (200 µg/d), Dietary Supplement: Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (400 µg/d)
- Where
- Algeria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Kasdi Merbah
Type 2 Diabetes
Glycaemic Control of Weekly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
The purpose of this study is to determine the optimal dose or doses of HM11260C, when administered once a week under the skin, to improve the control of blood sugar levels in patients with early-stage type 2 diabetes mellitus…
- Trial name
- NCT02057172
- Testing
- HM11260C, liraglutide
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Change in Fasting Plasma LDL-cholesterol Concentration After the Consumption of Quinoa
Effects of Quinoa Consumption on Markers of Cardiovascular Risk and Gastrointestinal Health
Quinoa is possible alternative to wheat, corn and rice due to its high nutritional value and possible properties against cardiovascular diseases and for improving gut health.
- Trial name
- NCT03036618
- Testing
- Quinoa, Wheat
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Type II Diabetes Mellitus
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
This study is testing whether a new medication called CX11 works and is safe for participants with type 2 diabetes who have not reached good blood sugar control while taking a steady dose of metformin, with or without a steady…
- Trial name
- NCT07340320
- Testing
- CX11
- Where
- 48 sites in United States, Poland
- Volunteers
- 240 people
- Sponsor
- Corxel Pharmaceuticals
Renal Transplantation
Prediction of NODAT After Renal Transplantation
A statistical analysis of the predictive value of OGTT and FPG testing executed as part of standard clinical practice after renal transplantation for the diagosis of new-onset diabetes mellitus after transplantation.
- Trial name
- NCT00442988
- Where
- Belgium
- Volunteers
- 360 people
- Sponsor
- KU Leuven
Gestational Diabetes
Early Gestational Diabetes Mellitus
In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) panel published consensus-based recommendations on the diagnosis and classification of hyperglycemia in pregnancy.
- Trial name
- LEMA_GDM (NCT04451915)
- Testing
- late management strategy, early management strategy
- Where
- 10 sites in France
- Volunteers
- 2,010 people
- Sponsor
- University Hospital, Lille
Diabetes Mellitus, Type 2
A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin
This study will evaluate the longer-term glycemic effect of two medicines approved for initial treatment of type 2 diabetes. The study consists of a 2 week screening period (2 study visits), followed by an 80 week double-blind…
- Trial name
- NCT00386100
- Testing
- Avandamet 6 mg/1500 mg (ttd), Avandamet 4 mg/1000 mg (ttd), Avandamet 2 mg/500 mg (ttd)
- Where
- 116 sites in United States, Argentina and 7 more
- Volunteers
- 688 people
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes, Novel Brominated Flame Retardants
Novel Brominated and Organophosphate Flame Retardants and Type 2 Diabetes
As alternative flame retardants (FRs), novel brominated flame retardants (NBFRs) and organophosphate flame retardants (OPFRs) are ubiquitous in environment and may cause endocrine disruption effects.
- Conditions
- Type 2 Diabetes, Novel Brominated Flame Retardants, Organophosphate Flame Retardants, Fasting Plasma Glucose
- Trial name
- NCT06239506
- Testing
- no intervention
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Xiaoling Guan
Physical Therapy
Reflexo Therapy for Gestational Diabetes Mellitus
The purpose of this study will be to detect the effects of Reflexo therapy of sole on GDM.
- Trial name
- NCT06976164
- Testing
- The standard antenatal care., Foot reflexology.
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Glucose and Lipid Metabolism, Incretin Hormones Plasma Levels
Effects of Aleurone-enriched Products on Cardiovascular Risk Factors
Very few studies have evaluated the effect of aleurone-enriched grains on cardiovascular risk factors. Price et al.(2010) have shown that 4-week supplementation of aleurone-enriched products (27 g/day of aleurone) increased…
- Conditions
- Glucose and Lipid Metabolism, Incretin Hormones Plasma Levels, Inflammation, Oxidative Stress and Endothelial Function
- Trial name
- NCT02150356
- Testing
- Aleurone, Control
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Federico II University
Pre-diabetes
7-Ketolithocholic Acid in Prediabetes
7-Ketolithocholic Acid, a naturally occurring bile acid, is a novel food currently under investigation for potential metabolic benefits, including glucose-lowering effects.
- Trial name
- NCT07650123
- Testing
- 7-KLCA, Diet and Physical Activity
- Where
- 8 sites in Italy
- Volunteers
- 100 people
- Sponsor
- ICE S.p.A.
Prediabetes (Impaired Fasting Glucose and/or Impaired Glucose Tolerance)
Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
The purpose of this study is to determine whether Rubus occidentalis extract could improve fasting or postprandial serum glucose levels, and related metabolic markers among patients with prediabetes (impaired fasting glucose…
- Trial name
- NCT01964703
- Testing
- Rubus occidentalis extract
- Volunteers
- 29 people
- Sponsor
- Korea University Anam Hospital
Early Pregnancy, Fasting Plasma Glucose
Effectiveness of a Lifestyle Intervention for Pregnant Women With Abnormal Glucose Metabolism in Early Pregnancy: EAGM Trial
This is a multicentre, parallel-group, open-label, pragmatic, randomised-control trial of early lifestyle intervention versus routine prenatal care by random allocation (1:1) in women with early abnormal glucose metabolism (EAGM)…
- Conditions
- Early Pregnancy, Fasting Plasma Glucose, Hemoglobin A1c Protein, Human, Lifestyle Intervention
- Trial name
- EAGM (NCT06767722)
- Testing
- Lifestyle intervention and self-monitoring of blood glucose
- Where
- China
- Volunteers
- 3,430 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Medical Nutrition Therapy, Gestational Diabetes Mellitus
Medical Nutrition Therapy Combined With TPF-DM in Pregnant Women With Gestational Diabetes Mellitus
Background: Gestational diabetes mellitus (GDM), GDM is the first time of gestational impaired glucose tolerance in pregnant women. It is the most common complication disease in women of childbearing age.
- Conditions
- Medical Nutrition Therapy, Gestational Diabetes Mellitus, Adverse Pregnancy Outcomes, Fasting Plasma Glucose
- Trial name
- NCT03957603
- Testing
- Enteral Nutrition Suspension (TFP-DM), Medical Nutrition Therpay
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Gestational Diabetes
Melatonin for Glycemic Control in Gestational Diabetes Mellitus
The goal of this randomized, double-blind, placebo-controlled clinical trial is to evaluate whether melatonin supplementation improves glycemic control in pregnant women diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- MELODY (NCT07369284)
- Testing
- Melatonin
- Volunteers
- 150 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Ischemic Heart Failure, Lipids
Serum Lipids and Glucose Levels in Relation to CVD Outcomes in Patients With Ischemic Heart Failure
Current prospective cohort study is to evaluate the association between fasting lipid profiles (including total cholesterol, low density lipoprotein-cholesterol, high density lipoprotein-cholesterol, triglycerides, apolipoprotein…
- Conditions
- Ischemic Heart Failure, Lipids, Fasting Plasma Glucose, Cardiovascular Outcomes
- Trial name
- NCT03206593
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Metabolic Control
Non-surgical Periodontal Therapy Effects Metabolic Control in Diabetics
The purpose of this study is to determine whether nonsurgical periodontal therapy is effective in the metabolic control of patients with type II Diabetes mellitus.
- Trial name
- NCT01252082
- Testing
- Scaling and Rootplaning
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Mashhad University of Medical Sciences