Clinical trials: Fat Loss
Cachexia, Neoplasms
Brown Adipose Tissue Activity and Energy Metabolism in Cachexia
To study BAT activity and energy metabolism in patients with cachexia induced by cancer or chronic disease.
- Conditions
- Cachexia, Neoplasms, Pulmonary Disease, Chronic Obstructive, Pancreatic Neoplasms
- Trial name
- BAT-Cachexia (NCT02500004)
- Testing
- 18F-FDG PET-MRI-imaging, DXA scanning, Abdominal subcutaneous adipose tissue biopsy
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Abdominal
Effects of Aerobic and Resistance Training on Abdominal Fat Loss
Study the effects of different exercise modes on total and regional adiposity variation in subcutaneous and visceral adipose tissue (VAT and SAT).
- Trial name
- NCT03700827
- Testing
- Resistance Training, Aerobic Training
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University Edwardsville
Obesity
Diet Induced Weight Loss to Reduce Inflammation in Obese Women
Breast cancer is one of the most frequently seen cancers in the United States. It occurs at all ages but is particularly common in post menopausal women.
- Trial name
- NCT01699906
- Testing
- Diet regimen to induce weight loss
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Facial Atrophy and Loss of Contour
Open Label, Multi-Center Study, Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Facial Fat Grafting
This is an open label multi-center study with the aim of evaluating the efficacy of adipose tissue processed with the SyntrFuge™ system in facial aesthetics and contouring.
- Trial name
- NCT05522426
- Testing
- SyntrFuge System
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Syntr Health Technologies, Inc.
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Progressive Metabolic Adaptations to Low Intensity Exercise Training and Weight Loss
the investigators first aim is to determine the effect of low intensity exercise (without weight loss) on insulin sensitivity, muscle lipid metabolism, and factors regulating these processes in skeletal muscle after 1 day, 2 wks…
- Trial name
- NCT01452074
- Testing
- Exercise Training, Weight Loss with continued Exercise Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Vascular Dysfunction
DNA Methylation and Vascular Function
The main objective is to examine DNA hypomethylation as an underlying mechanism for the increased production of inflammatory cytokines and the impaired vascular function in obese individuals and as a potential target for…
- Trial name
- NCT03527420
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Diet, Carbohydrate-Restricted
Effects of Diet Manipulation on Women in the Curves Program
The purpose of this study is to look at the effects of a carbohydrate restricted, high protein, high fat diet on weight loss and health outcomes in women participating in the Curves Fitness and Weight Loss Program.
- Trial name
- Curves2 (NCT03093792)
- Testing
- Control, American Heart Association plus exercise, Curves Complete - I plus exercise
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Weight Loss
The Effect of Time Restricted Feeding on Fat Mass in Overweight Women
Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours.
- Trial name
- NCT02629900
- Testing
- Time restricted feeding
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Obesity
Food Preference Following Bariatric Surgery
Roux-en-Y gastric bypass (RYGB) decreases appetite, caloric intake, glycemia, and body weight, all of which are maintained long term.It is controversial whether, after RYGB, patients choose to eat less high fat and sugary foods…
- Trial name
- NCT03363581
- Testing
- Food Preference
- Where
- Ireland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Evaluate the Safety and Tolerability, Healthy and Overweight or Obese Participants
Phase 1 Study of Ascending Doses of CMS-D008 in Healthy and Overweight/Obese Adults
This study is a first-in-human clinical trial of CMS-D008 conducted in Chinese healthy and overweight or obese adult participants, consisting of three parts: Part-1 Single Ascending Dose (SAD) study (hereinafter referred to as…
- Trial name
- NCT07518589
- Testing
- CMS-D008
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangzhe Biotechnology Co., Ltd.
Weight Loss
A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss
This study will examine whether, compared to a standard, low-fat, calorie-restricted diet intervention, the clinic-supported Ideal Protein weight loss method will result in greater weight loss and improvement in cardiometabolic…
- Trial name
- RENEWAL (NCT03515889)
- Testing
- Ideal Protein Weight Loss Method, Standard Weight Loss
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Overweight, Obesity
Effect of the Prescription of 10,000 Steps Per Day Using a Pedometer APP in the Body Composition of Overweight Adults
This study aimed the effect of the Accupedo pedometer smartphone app intervention, with goal setting of walking prescription of 10,000 steps per day, in overweight adults.
- Trial name
- NCT03845478
- Testing
- Control Group (CG), Intervention Group (IG)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Insulin Resistance, Obesity
Integrating the Genetic and Metabolic Faces of Obesity
The goal of this study is to determine why some obese individuals develop insulin resistance and others do not. We hypothesize that an impairment in differentiation of fat cells (adipocytes) is responsible for the development of…
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome
- Trial name
- NCT00285844
- Testing
- weight loss, thiazolidinedione
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University