Clinical trials: Fat Reduction
Overweight and Obesity
Safety and Efficacy of Glucosanol in Reducing Body Weight in Overweight and Obese Subjects
Glucosanol™, the medical device to be investigated contains a proprietary plant extract that is a natural inhibitor of alpha-amylase and can reduce starch digestion.
- Trial name
- NCT01407393
- Testing
- Glucosanol
- Where
- Germany
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Abdominal Obesity
Combination of Cryolipolysis and Aerobic Exercise in Reducing Abdominal Fat
The purpose of the study is To investigate the adding effect of Cryolipolysis to aerobic exercise with low caliorie diet on waist-to-hip ratio , ultrasonography, body mass index and skin fold of subcutaneous fat tissue in…
- Trial name
- NCT05852652
- Testing
- cryolipolysis and aerobic exercise
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Overweight or Obesity
Efficacy of a Nutritive Bar, in Reduction of Weight, Body Fat and Control of Appetite
The main objective of the trial is to measure the efficacy of a nutritive bar, in the reduction of weight, body fat and the control of appetite, in patients with overweight and obesity.
- Trial name
- NCT05104151
- Testing
- Nutritional bar, Healthy Habits Intervention
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Submental Fat
A Single Blind, Randomized, Placebo-controlled, Phase 2a, 2-cohort Study for the Evaluation of Safety and Efficacy of RZL-012 for Submental Fat Reduction in Healthy Volunteers.
Twenty-Eight (28) subjects (12 for cohort 1 and 16 for cohort 2 ) will be included in the study. Subjects in each cohort will be injected with a different dose of RZL-012.
- Trial name
- NCT04086823
- Testing
- RZL-012
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Raziel Therapeutics Ltd.
Subcutaneous Abdominal Adiposity
An Evaluation of the Safety and Efficacy of LIPO-102 for the Reduction of Subcutaneous Abdominal Adiposity
This is a double-masked evaluation of the safety and efficacy of LIPO-102 for the reduction of subcutaneous abdominal adiposity.
- Trial name
- NCT01096979
- Testing
- LIPO-102
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neothetics, Inc
Gynecomastia, Male Breast Enlargement
UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia)
Male volunteers who suffer from Pseudogynecomastia and seek noninvasive breast fat reduction will be enrolled into two arms to receive three biweekly UltraShape treatments.
- Trial name
- NCT02711605
- Testing
- UltraShape focused ultrasound device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Syneron Medical
Obesity, Steatosis
Effects of Fat and Carbohydrates in Obese Men
Obesity has become a global epidemic, and treating and preventing obesity appears to be one of the world's greatest challenges. The disorder is associated with a wide range of metabolic and hormonal changes, including the…
- Trial name
- FATFUNC (NCT01750021)
- Testing
- High fat low carbohydrate diet, Low fat high carbohydrate diet
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Obesity, Overweight
Development of Melt Organic Baking Fat for Reducing Child Obesity
The purpose of this study is to compare the effects of a cooking oil on metabolic rate, appetite, and metabolic risk markers.
- Conditions
- Obesity, Overweight, Pediatric Obesity
- Trial name
- NCT02346994
- Testing
- Melt Test Blend 3.2, Corn Oil
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Overweight, Obesity
High Fiber Rye Foods for Weight and Body Fat Reduction
The overall aim of this study is to investigate whether a diet rich in rye fiber from wholegrain rye, compared to refined wheat, as part of a hypocaloric diet leads to larger weight loss and lower body fat content after 12 weeks…
- Trial name
- RyeWeight (NCT03097237)
- Testing
- Wholegrain rye, Refined wheat
- Where
- Sweden
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Moderate to Severe Convexity of Submental Fat, Safety
Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat
The objectives of this study are to explore the safety and efficacy of subcutaneous injections of Deoxycholic Acid relative to placebo, in the submental area in patients with mild or extreme fullness of the submental fat and…
- Conditions
- Moderate to Severe Convexity of Submental Fat, Safety, Efficacy
- Trial name
- NCT02035267
- Testing
- Deoxycholic Acid
- Where
- 8 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Fat Reduction
Subcutaneous Sodium Deoxycholate Injections With or Without Triamcinolone for Reduction of Submental Fat
The subjects and evaluating investigator will be blinded to the treatment, thus maintaining double-blind status. By nature of the varying volumes of injection, the treating investigator will be unblinded to the treatment.
- Trial name
- NCT03241563
- Testing
- Sodium Deoxycholate, Triamcinolone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Body Fat Disorder
Subcutaneous Fat Reduction in the Submental Area
Study to Evaluate Non-Invasive Subcutaneous Fat Reduction in the Submental Area using Cryolipolysis. Healthy adult men and women with submental skin fold thickness > 1cm who desire reduction of submental fat.
- Trial name
- NCT02298322
- Testing
- CoolSculpting System
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity
Macronutrient Relations and Weight Loss in Obese Subjects
The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic…
- Trial name
- NCT00868387
- Testing
- energy-restricted, CHO-restricted diet, energy-restricted, CHO-rich diet
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Obesity, Hyperlipidemia
Lepticore in Metabolic Syndrome and Weight Loss
Metabolic syndrome is directly related to obesity. This study investigated the use of a plant based formulation to improve on the condition of people with metabolic syndrome.
- Conditions
- Obesity, Hyperlipidemia, Hyperglycemia
- Trial name
- NCT01046968
- Testing
- Lepticore
- Where
- Cameroon
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Yaounde 1
Abdominal Fat
Pivotal Study of the truSculpt Radiofrequency Device for Circumferential Reduction
To evaluate the safety and efficacy of the Cutera truSculpt radiofrequency device for circumferential reduction.
- Trial name
- NCT02873104
- Testing
- truSculpt rf device
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Central Abdominal Bulging
Evaluating the Safety and Efficacy of LIPO-202 for the Reduction of Central Abdominal Bulging Due to Subcutaneous Fat (AbCONTOUR2)
This is a multi-center, randomized, double-blinded, placebo-controlled study evaluating the safety and efficacy of LIPO-202 for the reduction of central abdominal bulging due to subcutaneous fat in non-obese subjects.
- Trial name
- NCT02398188
- Testing
- LIPO-202
- Where
- 35 sites in United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
HIV Infections, Insulin Resistance
Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance
The purpose of this study is to determine if, in men and women with excess abdominal fat and insulin resistance, people with HIV infection respond differently than people without HIV to interventions that typically improve body…
- Conditions
- HIV Infections, Insulin Resistance, Obesity
- Trial name
- NCT00264251
- Testing
- Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Abdominal Fat
VelaShape III Device in Comparison to Cryolipolysis for Circumferential Reduction
The purpose of this study is to compare the clinical performance of the VelaShape III device with CoolSculpt for reduction of the waist, love handles and flanks.
- Trial name
- NCT02143960
- Testing
- VelaShape III, CoolSculpt
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Fat Burn
Histological Evaluation of BTL-785F Device's Effect on Submental Subcutaneous Adipose Tissue
This study aims to evaluate the safety and effectiveness of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive reduction of subcutaneous submental fat.
- Trial name
- NCT06282172
- Testing
- Treatment with BTL-785-7
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.