Clinical trials: Fatigue, Mental
Depression, Anxiety
Simulated Dawn Med Students
Medical students score higher than the general population on measures of depression, anxiety, fatigue, poor sleep and sleepiness. Data suggest that disparages in circadian phase might contribute to these problems.
- Conditions
- Depression, Anxiety, Fatigue, Sleepiness
- Trial name
- NCT02088593
- Testing
- Simulated Dawn Light Box, Sleep Hygiene instructions
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Fatigue, Coping Behavior
Effect of Seated Exercises and Psychoeducational Rehabilitation on Fatigue and Coping of Women Postmastectomy
This study aimed to examine the effect of bundling seated exercises and psychoeducational rehabilitation using the teach-back approach on fatigue and coping of women postmastectomy. Hypotheses for research: 1.
- Trial name
- NCT06360276
- Testing
- Seated Exercises, Psychoeducational Rehabilitation, Routine Care
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Reserve, Aging
Cognitive Reserve and Post-Fatigue Recovery in Older Adults
As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent…
- Conditions
- Cognitive Reserve, Aging, Mental Fatigue, Fatigue
- Trial name
- NCT07667985
- Where
- Turkey (Türkiye)
- Volunteers
- 696 people, healthy volunteers welcome
- Sponsor
- Uşak University
Concentration Ability Impaired, Mental Fatigue
An Exploratory Investigation of a Supplement to Support Student Learning
In this trial, the herbal supplement (GeniusDrops) will be tested to see the effects it has on the dependent variables of interest.
- Trial name
- NCT05528094
- Testing
- GeniusDrops
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- JoySpring
Mental Fatigue, Alertness
Effect of Coffeeberry on Mood and Cognitive Performance
The primary aim of this randomised, double-blind, placebo-controlled, cross-over study is to assess the short-term cognitive effects of two beverages containing 100 and 300 mg coffeeberry extract (obtained from the fruit of the…
- Conditions
- Mental Fatigue, Alertness, Mood, Cognition
- Trial name
- NCT04975802
- Testing
- Coffeeberry, Caffeine
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Alert Fatigue, Health Personnel
Intervention Program for Alarm Fatigue in NICU Nurses Based on ABC-X Model
Monitors in newborn intensive care (NICU) help keep babies safe, but the constant beeping can overwhelm nurses. This 'alarm fatigue' makes it harder for nurses to identify real emergencies, stresses them out, and can impact…
- Trial name
- NCT07025863
- Testing
- Alarm Fatigue Intervention Program
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Guizhou Medical University
Menopause, Sleep Disturbance
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled, direct-to-consumer trial assessing the impact of health and wellness products on hormonal health and associated health outcomes in women with menopausal health issues
- Conditions
- Menopause, Sleep Disturbance, Anxiety, Depression
- Trial name
- NCT06749288
- Testing
- Radicle Revive Active Study Product 4.1 Usage
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Psychological Stress, Mental Fatigue
The Role of Physical Ardor in Triggering State Anattā and Psychophysiological Recovery
This study investigates how different types of aerobic exercise-specifically continuous treadmill running versus intermittent ball games-influence mental restoration in university students.
- Conditions
- Psychological Stress, Mental Fatigue, Self-Perception, Autonomic Nervous System Function
- Trial name
- SPAR (NCT07488169)
- Testing
- Continuous Aerobic Exercise (Treadmill-based), Intermittent Aerobic Exercise (Ball Games)
- Where
- China
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
Bilateral Vestibular Hypofunction
Effects of Structured Exercise Program in Bilateral Vestibular Hypofunction
Background: The vestibular rehabilitation is an exercise-based method, aiming to maximize central nervous system(CNS) compensation at vestibular nuclear and other CNS levels for vestibular pathology.
- Trial name
- NCT05853562
- Testing
- structured vestibular rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Miray Budak
Multiple Sclerosis
An Eight-week RCT of Home-based Pilates for Symptoms of Anxiety, Depression, and Fatigue Among People With MS
This study will investigate the effects of eight-weeks home-based Pilates on symptoms of anxiety, depression, and fatigue among people with Multiple Sclerosis.
- Trial name
- NCT04120207
- Testing
- Home-based Pilates, Delayed-start Pilates
- Where
- Ireland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Breastfeeding, Exclusive, Fatigue
MBSR and NLP, Postpartum Breastfeeding and Depression
The postnatal period is a risky period in which mothers experience regressive and progressive changes and rapid biopsychosocial changes.
- Conditions
- Breastfeeding, Exclusive, Fatigue, Sleep, Postpartum Depression
- Trial name
- postpartum (NCT06628986)
- Testing
- MBSR, NLP, control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Mental Fatigue, Muscle Strength Dynamometer
Acute Mental Fatigue and Muscle Strength
This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults.
- Trial name
- NCT07846618
- Testing
- Computer-Based Mental Fatigue Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Anxiety, Depression
Online Multi-component Psychological Intervention for Healthcare Workers During COVID-19 Pandemic
The objective of this study is to carry out a randomized clinical trial with healthcare workers in Mexico through a web platform.
- Conditions
- Anxiety, Depression, Sleep Disturbance, Quality of Life
- Trial name
- NCT04890665
- Testing
- Online psychological intervention for healthcare workers
- Where
- 3 sites in Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Red Tide, Neurologic Disorder
Investigating Health Impacts of Exposure to Harmful Algal Blooms
The goals of this project are to study the biological effects of environmental toxins (ET), in particular aquatic toxins such as brevetoxins (PbTx) and microcystin or their metabolites.
- Conditions
- Red Tide, Neurologic Disorder, Florida
- Trial name
- NCT06883227
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Psychological Phenomena: Central Fatigue
Impact of Varying Doses of Amino Acids on Exercise, Muscular and Mental Performance
A number of studies have shown that ingestion of crystalline amino acids, in particular branched chain amino acids (BCAA) can affect endurance performance, markers of muscle damage, and possibly mental focus.
- Trial name
- NCT01215396
- Testing
- AminoVital Amino Acid formulation, Amino Vital Amino Acid formulation
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cognitive Fatigue, Mental Fatigue
Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- FRESH (NCT05011318)
- Testing
- Baseline, Fatigue Manipulation
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Musculoskeletal Pain, Musculoskeletal Strain
Surgeon Ergonomics in Robotic-assisted Laparoscopic Vs Standard Laparoscopic Surgery
Musculoskeletal injuries amongst surgeons are prevalent. This project will determine whether Robotic-assisted Laparoscopic surgery (RALS) offers superior benefits to surgeon's musculoskeletal health than standard laparoscopic…
- Conditions
- Musculoskeletal Pain, Musculoskeletal Strain, Fatigue; Muscle, Heart, Cognitive Impairment
- Trial name
- MURALS (NCT04477746)
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Burnout Syndrome, Depression Disorder
The COMET Study: a Prospective COhort of MEdical residenTs to Assess Professional, Personal and Psychological Trajectories of Residents in General Internal Medicine
Introduction. Switzerland, like most Western countries, faces a paradox: an ageing, multimorbid population needs general internal medicine (GIM) physicians more than ever, yet fewer young doctors choose - and stay in - the…
- Conditions
- Burnout Syndrome, Depression Disorder, Insomnia, Perceived Stress
- Trial name
- COMET (NCT07707453)
- Where
- 3 sites in Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Fribourg