Clinical trials: Fatigue, Mental
Cancer
Sildenafil to Prevent and Reduce Cancer Related Cognitive Impairment
This study is examining the effects of standard of care cancer treatment as well as a medication called Sildenafil, on the cancer associated fatigue, cognition and the gut microbiome.
- Trial name
- SPARC (NCT06800092)
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stress, Fatigue
Measuring the Effect of Therapeutic Massage on Pain and Discomfort in Cardiac Cath Lab Staff
The purpose of this study is to evaluate the effect of therapeutic massage in alleviating musculoskeletal pain and discomfort associated with wearing lead aprons in the cardiac cath lab.
- Conditions
- Stress, Fatigue, Anxiety
- Trial name
- NCT01048164
- Testing
- Massage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromyalgia Syndrome, Fibromyalgia
Pain & Reward Neuromodulation of CNS Circuits
This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS).
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
- Trial name
- PRANCIR (NCT07525063)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Stress, Fatigue
Measuring the Effect of Chair Massage on Stress Related Symptoms for Nurses
The purpose of this study was to assess the feasibility and effect of chair massage provided during working hours for nurses in an inpatient psychiatric and an outpatient pain rehabilitation unit and on the nurses stress related…
- Conditions
- Stress, Fatigue, Anxiety, Tension
- Trial name
- NCT01504763
- Testing
- Chair massage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Myeloma
A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg
1. Planned enrollment period One year (The planned number of patients to be enrolled is set to 400 patients.) Since all patients who are prescribed with Pomalyst are registered in RevMate®, enrollment using the Registration Form…
- Trial name
- NCT02921828
- Where
- 2 sites in United States, Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Cancer Survivor, Fatigue
Home-Based Programs for Improving Sleep in Cancer Survivors
RATIONALE: Following a program that uses written materials and pre-recorded mp3 devices may help improve the sleep of cancer survivors.
- Conditions
- Cancer Survivor, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders
- Trial name
- NCT00993928
- Testing
- Home-based sleep intervention
- Where
- 193 sites in United States
- Volunteers
- 93 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Fatigue Syndrome, Chronic, Healthy
Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression
Major depression represents a major public health problem worldwide and in the U.S. Fifteen percent of the U.S. population has depression at some point in life (40 million individuals).
- Conditions
- Fatigue Syndrome, Chronic, Healthy, Mood Disorders
- Trial name
- NCT00001479
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Long-COVID, Brain Fog
Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID
Approximately 30% of patients experience "Long-COVID" syndrome presenting with symptoms such as cognitive difficulties ('brain fog'), fatigue, dyspnea, autonomic dysfunction, depression and anxiety, lasting beyond 12 weeks…
- Conditions
- Long-COVID, Brain Fog, Cognition, Memory
- Trial name
- NCT07429903
- Testing
- whole food - walnuts
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Los Angeles
Chronic Obstructive Pulmonary Disease (COPD)
Neuromuscular Fatigue in Chronic Obstructive Pulonary Disease
Fatigue is a prevalent symptom in Chronic Obstructive Pulmonary Disease (COPD) that limits patients in their daily living activities.
- Trial name
- NEUROTIGUE (NCT04028973)
- Testing
- Single then dual task situation, Dual then single task situation
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Burnout, Caregiver, Compassion Fatigue
Exercise for Oncology Care Professionals
The goal of this preference-based pilot study will be to assess the feasibility and acceptability, and impact of a 12-week exercise intervention on oncology care provider burnout.
- Trial name
- C4C+ (NCT05884073)
- Testing
- Circuit-based Resistance Training, Nature-based Walking
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Melanie Keats
Environmental Toxins, General Health
Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols
The primary purpose of this study is to evaluate the effects of CellCore protocols on environmental toxicant biomarkers among adult patients with high baseline toxicant levels.
- Trial name
- NCT07753798
- Testing
- CellCore Foundational Protocol, CellCore - BioToxin Binder & Drainage Activator
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- OvationLab
Mental Fatigue, Electroencephalography
The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance
The purpose of this project is to provide further insights into the neurophysiology behind the MF-induced impairment in endurance performance.
- Trial name
- NCT04719975
- Testing
- Mental Fatigue (Stroop task), Control (Documentary)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Heart Diseases
Different Intensities of Continuous Aerobic Exercises in Cardiac Rehab Phase 2
To determine the effects of different intensities of Continuous Aerobic Exercises on Fatigue levels, Mental Well- Being \& Mindfulness in Cardiac Rehab Phase 2.
- Trial name
- NCT04624412
- Testing
- Continuous Aerobic Moderate Intensity Exercise, Continuous Aerobic (Mild intensity Exercise)
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Riphah International University
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Landing Biomechanics, Fatigue
The Effect of Cognitive Dual Task and Mental Fatigue on Landing Biomechanics
In this study, three-dimensional biomechanics , by means of lower limb joint angles and moments (opto-electronic system with synchronised force plate), of landing tasks (anticipated, unanticipated and cognitive dual task) before…
- Trial name
- NCT04674007
- Testing
- 3D analysis of landing task
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Ghent
Colorectal Cancer
Effect of Aromatherapy Massage on Symptom Control
Although the incidence of colorectal cancers is high, it is often possible to treat it when diagnosed at an early stage. Although the treatment options vary according to many factors such as the type and stage of the cancer…
- Trial name
- NCT04810299
- Testing
- Aromatherapy, Classical foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Agricultural Workers' Diseases, Posture
Examination of Pain, Posture, Physical and Mental Status in Seasonal Hazelnut Workers
The collection of hazelnuts grown in our country provides a great source of employment for local people and seasonal workers. However, geographical conditions in hazelnut growing areas, challenging variable weather conditions in…
- Conditions
- Agricultural Workers' Diseases, Posture, Pain, Depression
- Trial name
- NCT06289465
- Testing
- Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Quiet Quitting, Fatigue, Compassion
Physical Fatigue, Compassion Fatigue, and Quiet Quitting in Physiotherapists
Physiotherapists are exposed to both physical and emotional demands due to the nature of their profession. Repetitive physical workload, prolonged standing, patient handling, and continuous interaction with patients may…
- Conditions
- Quiet Quitting, Fatigue, Compassion, Work Engagement
- Trial name
- NCT07340866
- Testing
- No Intervention (Observational Study)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Stroke
Predicting Cognitive Development in Younger Stroke Patients Using the Oxford Cognitive Screen
The purpose of this study is to investigate whether Oxford Cognitive Screen (OCS) can be used as a predictive tool during hospital admission in younger (<65 years) stroke patients, i.e.
- Trial name
- STROKY (NCT05612815)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Bispebjerg Hospital