Clinical trials: Fatigue, Mental
Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome
Effect of Stellate Ganglion Block on ME/CFS
The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Conditions
- Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome, Chronic Fatigue Disorder, Chronic Fatigue and Immune Dysfunction Syndrome
- Trial name
- SGB_ME (NCT05664711)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neuroversion, Inc.
Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain
Neuropsychological Outcome After Cardiac Arrest
This study is a sub-study to the large pragmatic Target Temperature Management 2 Trial (TTM2-trial, ClinicalTrials.gov Identifier: NCT02908308), assessing effectiveness of controlled hypothermia after out-of-hospital cardiac…
- Conditions
- Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain, Cognition Disorders, Psychological Distress
- Trial name
- NCT03543371
- Testing
- Neuropsychological assessment
- Where
- 8 sites in Denmark, Sweden and 1 more
- Volunteers
- 200 people
- Sponsor
- Region Skane
Fibromyalgia
Pranayama and Diaphragmatic Breathing Exercise Applied to Female Patients With Fibromyalgia
Female patients diagnosed with fibromyalgia were divided into pranayama breathing exercise, diaphragm breathing exercise and control groups.
- Trial name
- NCT05840939
- Testing
- Pranayama, diaphragm breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Mental Fatigue, Adolescent Behavior
Benefits of Physical Activity During the School Day to Reduce Mental Fatigue and Optimize Cognitive and Psychosocial Processes in Secondary School Students
The main aim of the MENTALFIT project is to test the effectiveness of physically active teaching methodologies to reduce mental fatigue and optimize cognitive, emotional, and motivational processes in secondary school students.
- Conditions
- Mental Fatigue, Adolescent Behavior, Physical Inactivity
- Trial name
- MENTALFIT (NCT07427329)
- Testing
- Active breaks, Physically active learning, Active Recess
- Where
- Spain
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Depression, Fatigue
Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer
RATIONALE: Measuring levels of interleukin-6 and depression may help doctors understand the relationship between interleukin-6 and depression. It may also help the study of cancer in the future.
- Conditions
- Depression, Fatigue, Ovarian Cancer, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00460200
- Testing
- polymorphism analysis, laboratory biomarker analysis, physiologic testing
- Sponsor
- Jonsson Comprehensive Cancer Center
Post COVID-19 Condition, Cognitive Impairment
Cognitive Impairment and Fatigue After Mild to Moderate COVID-19
The primary aim of the project is to map fatigue, cognitive and visual dysfunctions and possible underlying pathophysiological mechanisms in persons with long-term symptoms after a mild to moderate COVID-19 infection.
- Conditions
- Post COVID-19 Condition, Cognitive Impairment, Fatigue, Mental
- Trial name
- NCT06042530
- Testing
- Neuropsychological investigation, Optometric investigation, Magnetic Resonance Imaging
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Fatigue
Tolerability and Benefit of IQP-AS-121 on Fatigue and Mental Alertness
The purpose of this study is to evaluate the tolerability and benefit of IQP-AS-121 on reducing fatigue and tiredness and to improve mental alertness.
- Trial name
- NCT02871271
- Testing
- IQP-AS-121
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- InQpharm Group
Long COVID
Neurobiological Underpinnings of Neuropsychological Consequences in Long COVID
Objectives: To describe the standardized evaluation of the psychological and cognitive function of long COVID patients and their evolution, to compare immunological and HPA-axis related biomarkers between long COVID patients and…
- Trial name
- Cov-N-Psy (NCT06279936)
- Testing
- Neuropsychological battery, Surveys and symptom severity questionnaires, Blood withdrawal
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
COVID-19
Do EEG and Neurocognitive Assessments Correlate With COVID Brainfog Symptoms?
Since the neurologic symptoms of some COVID patients ('brain fog') resemble those of patients with concussion, the aim of this study is to identify EEG and cognitive function changes in COVID patients.
- Trial name
- NCT05303116
- Testing
- Brainscope modified EEG and cognitive testing
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
SARS-CoV-2 Infection, COVID-19 Recurrent
Efficacy of a Physical and Respiratory Rehabilitation Program for Patients With Persistent COVID-19 (SARS-CoV-2).
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of a plethora of persistent, diffuse and heterogeneous symptoms such as fatigue, shortness of breath and…
- Conditions
- SARS-CoV-2 Infection, COVID-19 Recurrent, Cognitive Dysfunction, Fatigue
- Trial name
- COPERIA-REHAB (NCT05629884)
- Testing
- COPERIA-REHAB
- Where
- 4 sites in Spain
- Volunteers
- 56 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Compassion Fatigue
A Predictive Model for Midwives' C F: A Cross-Sectional Study
Compassion fatigue is a professional psychological problem caused by long-term work pressure, resulting in emotional exhaustion and a decline in empathy ability.
- Trial name
- NCT07234344
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- LanZhou University
Performance Enhancing Product Use
Effect of a New Formulation of Vitamin B12 on Physical and Mental
This clinical study evaluates the effect of acute intake of a new vitamin B12 formulation on anaerobic and cognitive performance variables.
- Trial name
- PERB12 (NCT06639789)
- Testing
- Vitamin B12 (B12)
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Lactate Blood Increase, Trauma Blunt
Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention
Serum lactate has been utilized as a standard in guiding management of orthopedic injuries. Elevated preoperative lactate has been associated with a higher likelihood of postoperative complications.
- Conditions
- Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
- Trial name
- NCT05611398
- Testing
- Orthopedic Surgery
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Arrowhead Regional Medical Center
Fibromyalgia
Fibromyalgia Treatment Trial With Gabapentin and Osteopathic Manipulative Medicine
This study assesses the benefits of intervention with gabapentin, Osteopathic Manipulative Medicine or both for improvement of the symptoms of Fibromyalgia.
- Trial name
- FTTGO (NCT01107574)
- Testing
- Gabapentin, Osteopathic Manipulative Medicine, Gabapentin and Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Systemic Lupus Erythematosus, Depression
LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE
The purpose of this study is to investigate the effects of a type of non-invasive transcranial alternating current stimulation (tACS) on patients diagnosed with systemic lupus erythematosus (SLE) who are experiencing depression.
- Trial name
- NCT04141046
- Testing
- XCSITE100 Stimulator - Individualized theta-tACS, XCSITE100 Stimulator - Individualized alpha-tACS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Survivorship, Cognitive Dysfunction
Biobehavioral Correlates of Cancer-related Cognitive Dysfunction and Its Co-occurring Symptoms
This descriptive, cross-sectional study will evaulate and fully characterize factors associated with cognitive dysfunction in Breast Cancer (BCS) and Colorectal Cancer (CRC) survivors that have cognitive concerns, and factors…
- Conditions
- Survivorship, Cognitive Dysfunction, Pain, Depression
- Trial name
- NCT04611620
- Testing
- Cognitive Dysfunction
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- Indiana University
Fatigue, Cognitive Function
Radicle Energy VBMTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
Radicle Energy VBMTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes.
- Conditions
- Fatigue, Cognitive Function, Global Mental Health, Sleep Disturbance
- Trial name
- NCT07653724
- Testing
- Energy Active Product 1
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Brain Cancer
Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients
This goal of this research study is to learn more about fatigue, sleep quality, and other symptoms in patients with primary brain tumors who are being treated with radiation therapy. Objectives: PRIMARY OBJECTIVE: 1.
- Trial name
- NCT00876499
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Anxiety Depression, Post Traumatic Stress Disorder
Neuropsychological Sequelae and Long COVID-19 Fatigue
An association of fatigue with post-viral neuropsychological disturbs has been reported. Among patients hospitalized with COVID-19 there is an increased incidence of anxiety and depression symptoms.
- Conditions
- Anxiety Depression, Post Traumatic Stress Disorder, Mental Fatigue, COVID-19
- Trial name
- PostCoV2Psy (NCT05323318)
- Testing
- Neuropsychological Sequelae
- Where
- 6 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Universitario do Algarve