Clinical trials: Fatigue
Pre-diabetes, Type 2 Diabetes
Mechanisms of Fatigability With Diabetes
Pre-diabetes (Pre-D) is a precursor to type 2 diabetes (T2D) and characterized by increased exercise fatigability of lower limb muscles, that can impede exercise performance.
- Trial name
- NCT04442451
- Testing
- Control Exercise, Blood Flow Restriction Exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Body Temperature Changes, Heat Stress
Consecutive Occupational Heat Exposure With and Without Overnight Cooling
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07656519
- Testing
- Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Menstrual Cramps, Women's Health
A Study to Assess the Effect of My Happy Flo on Alleviating Period Symptoms and Heavy Flows.
This clinical study aims to evaluate the effectiveness of My Happy Flo, a dietary supplement, in alleviating period symptoms and heavy menstrual flows.
- Conditions
- Menstrual Cramps, Women's Health, Fatigue
- Trial name
- NCT06522672
- Testing
- My Happy Flo
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- My Happy Flo
Health Behavior, Health-Related Behavior
Sleep for Optimal MEdical StudentS (PROMESS)
Medical students have been shown to have a greater prevalence of poor sleep leading to poorer quality of life than other groups of students.
- Conditions
- Health Behavior, Health-Related Behavior, Sleep, Sleep Disorder
- Trial name
- NCT06297330
- Testing
- Sleep
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Research on Healthcare Performance Lab U1290
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Long COVID
Feasibility of Personalised Health Behaviour Coaching to Support Symptoms and Activities of Daily Living in Those With Long COVID-19.
This pilot RCT aims to assess whether a simple PA behavioural modification intervention can be delivered safely and feasibly to individuals with Long COVID suffering long standing symptoms with concerns regarding their ability to…
- Trial name
- NCT05752331
- Testing
- Physical activity behavioural modification
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Bournemouth University
Surgical Intervention
Assessment of Surgeons' Mental Fatigue Based on Operating Time
In May 2023, the French National Authority for Health published a solution for patient safety regarding tunnel vision. This concept, which is uncommon in the medical field, is defined as any situation in which a professional's…
- Trial name
- COGNICHIR (NCT07228767)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Work-Related Condition, Physical Stress
Wearable Robotic Upper Body Exoskeleton for Workers
The main aim of the project is to evaluate a novel upper body exoskeleton during simulated industrial work. In a first stage of the project, an extensive study involving the end-user companies will be carried out to clearly…
- Conditions
- Work-Related Condition, Physical Stress, Mental Fatigue
- Trial name
- Exo4Work (NCT03491501)
- Testing
- Ergonomic evaluation using questionnaires
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Heart Arrest, Cardiac Arrest
An Intervention for Cardiac Arrest Survivors With Chronic Fatigue
The primary aim was to examine the feasibility of an Energy Conservation + Problem Solving Therapy (EC+PST) intervention delivered over the telephone and to evaluate the preliminary intervention effect on fatigue impact in daily…
- Conditions
- Heart Arrest, Cardiac Arrest, Fatigue
- Trial name
- CAF (NCT02864719)
- Testing
- Energy Conservation+Problem Solving Therapy
- Volunteers
- 18 people
- Sponsor
- University of Pittsburgh
Fatigue, Metastatic Prostate Carcinoma
Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients
This trial studies how well resistance training with or without creatine monohydrate supplement works in improving body composition and health outcomes in patients with prostate cancer that has spread to other places in the body.
- Conditions
- Fatigue, Metastatic Prostate Carcinoma, Sedentary Lifestyle, Stage IV Prostate Cancer AJCC (American Joint Committee on Cancer) v8
- Trial name
- NCT03987217
- Testing
- Creatine Monohydrate, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Utah
Fatigue
Alterations in Spiking Following Muscle Fatigue in Volleyball Players
This study aims (1)to investigate the effects of repetitive functional overhead movements targeting shoulder and scapular muscles on glenohumeral and scapular kinematics and muscle activation during the arm cocking and…
- Trial name
- NCT07687550
- Testing
- Upper Extremity Muscle Fatigue Protocol
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Brain Fog
Transcranial Direct Current Stimulation (tDCS)
Cognitive impairment refers to when an individual struggles to learn, concentrate, remember, or make decisions. This can be due to underlying neurological diseases (i.e.
- Trial name
- tDCS (NCT05524233)
- Testing
- Active Transcranial Direct Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Fatigue
Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms
Radicle Women's HealthTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes among women experiencing menopausal…
- Trial name
- NCT07572578
- Testing
- Fatigue Active Product 1
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Healthy
Respiratory Muscle Fatigue at Different Breathing Modes
The study aims at investigating if time to respiratory muscle fatigue and metabolism are influenced by the pressure wave form mode applied during resistive breathing.
- Trial name
- NCT05393115
- Testing
- Square wave breathing
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Insomnia, Cancer
The Sleepio After Cancer Study
This study will recruit women over the age of 18 with a current or prior cancer diagnosis who have clinical insomnia. This study will examine the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I) compared to…
- Trial name
- SACS (NCT05816460)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I), Sleep Hygiene Education (SHE)
- Where
- Ireland
- Volunteers
- 308 people
- Sponsor
- University College Dublin
Fatigue
Radicle Energy™ 24_RCA: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes
- Trial name
- NCT07166523
- Testing
- Energy Active Product 1
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Depression, Fatigue
Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia
RATIONALE: An individualized exercise program may be effective in lessening fatigue and depression and improving quality of life in patients undergoing chemotherapy for leukemia.
- Conditions
- Depression, Fatigue, Leukemia, Musculoskeletal Complications
- Trial name
- NCT00499759
- Testing
- Resting vitals, Body Composition, Timed Get-up and Go test (TGUG).
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Head and Neck Neoplasms, Cancer-related Fatigue
Tai Chi for Cancer-Related Fatigue During Radiotherapy in Patients With Head and Neck Cancer
This prospective, randomized controlled study will evaluate whether a Tai Chi exercise program can help reduce cancer-related fatigue in patients with head and neck cancer undergoing radiotherapy.
- Trial name
- NCT07809776
- Testing
- Tai Chi Intervention Group, Usual Care and Health Education
- Where
- China
- Volunteers
- 116 people
- Sponsor
- West China Hospital
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Progressive Muscle Relaxation Technique
Investigation of The Effect of Progressive Muscle Relaxation Technique in Sedentary Obese Women
Obesity is a major public health problem that reduces quality of life and increases the risk of many chronic diseases. Its global prevalence continues to rise, and it is estimated that approximately 18 percent of men and 21…
- Trial name
- NCT07244718
- Testing
- Control, Music-Assisted Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Pamukkale University