Clinical trials: Fatigue Intensity, active
Cognitive Dysfunction, Acquired Brain Injury
Fareon Open Label Device Clinical Trial
The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis…
- Conditions
- Cognitive Dysfunction, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- NCT07600320
- Testing
- Fareon device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Physical Fatigue
Effects of Upper Extremity Flywheel Exercises on Skills, Muscle Oxygenation, and Fatigue in Adolescent Basketball
This study will investigate the effects of flywheel exercises targeting the upper extremities on athletic performance, muscle oxygenation, physical fatigue, and muscle strength in adolescent basketball players.
- Trial name
- Flywheel (NCT07331012)
- Testing
- Flywheel Exercises, Traditional Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istinye University
Spasticity of the Plantar Flexors
Impact of a Sequential Isokinetic Fatigue Protocol Followed by Ankle Strengthening After Botulinum Toxin Injection Into Spastic Plantar Flexors on Foot Lift Strength and Walking
Spastic foot drop (speed- and force-dependent hypertonia) is one of the most common neuro-orthopaedic disorders following brain injury.
- Trial name
- ISOTOX (NCT07260565)
- Testing
- Isokinetic rehabilitation protocol., standard rehabilitation programme
- Volunteers
- 30 people
- Sponsor
- Clinique Victor Pauchet
Breast Cancer, Cancer Related Fatigue
Feasibility of 'Exercise for CAncer Patients and Healthy EAting Timeframes' .
This study evaluates the feasibility and preliminary effects of a home based exercise and activity program for individuals with cancer.
- Trial name
- EXCAP-hEAT (NCT07529353)
- Testing
- EXCAP Exercise Program, 10-Hour Healthy Eating Timeframe (hEAT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Fatigue Syndrome, Chronic
Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort
Background: The way the brain processes rewards and punishments may play a role in some disorders of the nervous system. People with chronic overlapping pain conditions (such as myalgic encephalomyelitis/chronic fatigue syndrome…
- Trial name
- NCT06472622
- Testing
- Thermal Pain Stimulation, Physical Effort Stimulation
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Post-Stroke Fatigue
Graded Activity Training and Task- Oriented Training on Post-Stroke Fatigue
The aim of this randomized controlled trial is to determine the effects of Graded Activity Training and Task Oriented Training on Fatigue in Post-Stroke Patients.
- Trial name
- NCT06846177
- Testing
- Graded Activity Training, Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Pediatric Cancer Patients
Evaluation of an Exercise Intervention During Intensive Medical Treatment in Pediatric Oncology.
The BEPPO study is a Germany-wide clinical trial investigating whether a structured exercise program can improve physical and mental health in children and adolescents undergoing cancer treatment.
- Trial name
- BEPPO (NCT07647471)
- Testing
- Partially-standardised, supervised, continuity-of-care exercise intervention
- Where
- 13 sites in Germany
- Volunteers
- 346 people
- Sponsor
- Universität Duisburg-Essen
Multiple Sclerosis, Fatigue in Multiple Sclerosis
Non-invasive Brain Stimulation in Multiple Sclerosis Fatigue
The neurobiological basis of central fatigue in multiple sclerosis remained unclear so far. This study investigates reward-related brain mechanisms, inflammation, and their modulation by non-invasive brain stimulation using fMRI…
- Trial name
- NCT07438964
- Testing
- tDCS of dlPFC
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Charite University, Berlin, Germany
Metastatic Prostate Cancer
Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)
The study is being done to see if a small daily dose of naltrexone (LDN, 3 mg pill) can help reduce tiredness (fatigue) in men with prostate cancer.
- Trial name
- NCT07224009
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Arkansas
Muscle Fatigue (C23.888.592.612.612), Muscle Weakness or Atrophy
A Biomechanical Study of Collaborative FES on Lower Limb Motor Function in the Elderly
This study will first conduct a precise assessment of the differences in muscle coordination among the elderly through muscle synergy analysis; then, based on this, it will extract abnormal synergy patterns and muscle activation…
- Trial name
- NCT07245602
- Testing
- Collaborative Functional Electrical Stimulation, Traditional functional electrical stimulation
- Volunteers
- 30 people
- Sponsor
- Chen Xuan
Chronic Fatigue Syndrome
Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue
Chronic fatigue is enhanced by adapted physical activity (APA) programs. Patients consulting on St Etienne hospital and suffering from fibromyalgia and long Covid benefit from a 4-6 week APA program, with 2 sessions per week.
- Trial name
- PAF-tVNS (NCT06170645)
- Testing
- APA program, Active transcutaneous VNS
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hypothyroidism Primary
Physical Activity, Fatigue, Social Support, and Psychological Well-Being in Women With Primary Hypothyroidism
Background. Primary hypothyroidism, both clinical and subclinical, is frequently associated with persistent fatigue, reduced psychological well-being, and lower levels of physical activity in adult women.
- Trial name
- NCT07408765
- Testing
- Women with primary hypothyroidism sample
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- University of Oviedo
Multiple Sclerosis
Relationship Between Single- and Dual-Task Obstacle Crossing Performance and Fatigue and Disability in Multiple Sclerosis
This cross-sectional observational study aims to investigate the relationship between obstacle crossing performance under single-task and dual-task conditions and the levels of fatigue and disability in individuals with…
- Trial name
- NCT07736482
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Afyonkarahisar Health Sciences University
Multiple Sclerosis, Depression - Major Depressive Disorder
Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis
Canada has one of the highest rates of multiple sclerosis (MS). MS patients experience disabling motor, visual, and sensory symptoms, and a high risk of comorbid major depressive disorder (MDD) and severe fatigue.
- Conditions
- Multiple Sclerosis, Depression - Major Depressive Disorder, Fatigue
- Trial name
- NCT07562074
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Post-dialysis Fatigue
we Use Recovery Time to Assess Post-dialysis Fatigue and we Use Also Two Different Fatigue Scales 1- Visual Analogue Scale 2- Fatigue Severity Scale and we Address Risk Factors of PDF and Apply the Scales on Regular Hemodialysis Patients in Hemodialysis Unit of Assiut University Hospital
To improve the quality of life of hemodialysis patients and provide better control for post dialysis fatigue in regular hemodialysis patients.
- Trial name
- NCT06947681
- Volunteers
- 155 people
- Sponsor
- Assiut University
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME), Post COVID Syndrome
Effectiveness and Safety of a Tele-Rehabilitation Program on Fatigue and Related Variables in Chronic Fatigue Syndrome and Post COVID Syndrome
This is a randomized, single-blind clinical trial that aims to evaluate the effectiveness of a tele-rehabilitation program based on mindful and conscious movement-based exercise (including adapted yoga, breathing exercises, and…
- Trial name
- NCT06978582
- Testing
- Mindful and conscious movement-based exercise, Conventional exercise
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- University of Seville
Cancer-related Problem/Condition, Fatigue in Cancer Survivors
Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors
The purpose of the study is to evaluate whether EnergyPoints, a mobile phone health app that guides the participant to do self-acupressure, can decrease fatigue and improve sleep.
- Conditions
- Cancer-related Problem/Condition, Fatigue in Cancer Survivors, Sleep Disturbances, Health-related Quality of Life
- Trial name
- NCT06754722
- Testing
- App to guide self-acupressure
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- 5 Point App, Inc.
Stroke, Fatigue
Behavioral and Neural Correlates of Post-Stroke Fatigue
The goal of this phase I/II clinical trial is to determine the behavioral and neural effects of 5-daily transcranial direct current stimulation on post-stroke fatigue.
- Trial name
- NCT06088914
- Testing
- Anodal transcranial direct current stimulation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Texas Woman's University
Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe
Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders
The aim of this multi-center, two-armed, randomized controlled trial is to assess the effect of a novel internet-based therapist-assisted treatment program "One step at a time" designed for the treatment of patients with moderate…
- Conditions
- Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe, Fibromyalgia, Chronic Fatigue Syndrome
- Trial name
- OneSTEP (NCT05525598)
- Testing
- "One step at a time", "Get started"
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- University of Aarhus
Sjögren´s Disease
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
The purpose of this study is to demonstrate the efficacy and safety of ianalumab (VAY736) 300 mg administered subcutaneously (s.c.) monthly for 52 weeks in adult participants with Sjögren's disease who have high symptom burden.
- Trial name
- THALASSA (NCT07621809)
- Testing
- VAY736
- Where
- 33 sites in United States, Australia and 6 more
- Volunteers
- 570 people
- Sponsor
- Novartis Pharmaceuticals